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公开(公告)号:US20130053395A1
公开(公告)日:2013-02-28
申请号:US13560119
申请日:2012-07-27
申请人: Juan-Miguel Jimenez , Julian M.C. Golec , Luca Settimo , Damien Fraysse , Guy Brenchley , Dean Boyall , Heather Twin , Stephen Young , Andrew W. Miller , Christopher John Davis , Philip N. Collier
发明人: Juan-Miguel Jimenez , Julian M.C. Golec , Luca Settimo , Damien Fraysse , Guy Brenchley , Dean Boyall , Heather Twin , Stephen Young , Andrew W. Miller , Christopher John Davis , Philip N. Collier
IPC分类号: A61K31/496 , A61P37/06 , A61P29/00 , A61P35/00 , A61P11/06 , A61P19/04 , A61P19/02 , A61P25/00 , A61P3/10 , A61P1/00 , A61P35/02 , C07D471/04 , A61P17/06
CPC分类号: C07D471/04
摘要: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
摘要翻译: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病,病症或病症的方法。 本发明还提供了制备本发明化合物的方法。
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公开(公告)号:US08809335B2
公开(公告)日:2014-08-19
申请号:US13560131
申请日:2012-07-27
申请人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
发明人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
IPC分类号: A61K31/497
CPC分类号: C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
摘要翻译: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病,病症或病症的方法。 本发明还提供了制备本发明化合物的方法。
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公开(公告)号:US08895740B2
公开(公告)日:2014-11-25
申请号:US13560122
申请日:2012-07-27
申请人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
发明人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
IPC分类号: C07D487/04 , A61K31/4985
CPC分类号: C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
摘要翻译: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病,病症或病症的方法。 本发明还提供了制备本发明化合物的方法。
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公开(公告)号:US20130053394A1
公开(公告)日:2013-02-28
申请号:US13560131
申请日:2012-07-27
申请人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
发明人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
IPC分类号: A61K31/519 , A61P37/00 , A61P29/00 , A61P35/00 , A61P11/06 , A61P35/02 , A61P19/02 , A61P25/00 , A61P3/10 , A61P1/00 , A61P37/06 , C07D487/04 , A61P17/06
CPC分类号: C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
摘要翻译: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病,病症或病症的方法。 本发明还提供了制备本发明化合物的方法。
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公开(公告)号:US20130053388A1
公开(公告)日:2013-02-28
申请号:US13560122
申请日:2012-07-27
申请人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
发明人: Juan-Miguel Jimenez , Luca Settimo , Damien Fraysse , Guy Brenchley , Christopher John Davis , Andrew W. Miller
IPC分类号: A61K31/4985 , A61P37/06 , A61P29/00 , A61P35/00 , A61P11/06 , A61P19/04 , A61P19/02 , A61P25/00 , A61P3/10 , A61P1/00 , A61P35/02 , C07D487/04 , A61P17/06
CPC分类号: C07D487/04
摘要: The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
摘要翻译: 本发明涉及可用作蛋白激酶抑制剂的化合物。 本发明还提供包含所述化合物的药学上可接受的组合物和使用该组合物治疗各种疾病,病症或病症的方法。 本发明还提供了制备本发明化合物的方法。
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公开(公告)号:US20120208163A1
公开(公告)日:2012-08-16
申请号:US13098108
申请日:2011-04-29
申请人: Karen E. Dwyer , Theresa A. Cepaitis , Carrie D. Booth , Margaret M. Gaudino , Gary P. Smith , Richard M. Jolles , David K. Kreisberg , Vivian C. Rosskamm , Andrew W. Miller , Maria L. Tarasuk
发明人: Karen E. Dwyer , Theresa A. Cepaitis , Carrie D. Booth , Margaret M. Gaudino , Gary P. Smith , Richard M. Jolles , David K. Kreisberg , Vivian C. Rosskamm , Andrew W. Miller , Maria L. Tarasuk
IPC分类号: G09B19/00
CPC分类号: G06Q10/101 , G06Q50/205 , G09B5/00 , G09B7/00
摘要: A system and method for comprehensive, fully or partially automated instructional plan creation, management, and tracking is provided. Variations of the system may include specialized computer systems, specialized applications, or web-based server-side solutions. Variations of the method may include generation of integrated or course-based instructional plans based on a relationship between standards and indicators of educational success and an academic schedule divided into schedule units. Instructional plans may be populated with learning and teaching resources from a content repository. Such population may be automated, customized, based on user settings, and otherwise configurable on a per-instructor basis. Instructors may also load content into the repository, associate content with one or more identifying parameters, and collaborate with each-other based on teaching style and resource choices.
摘要翻译: 提供了全面,全面或部分自动化教学计划创建,管理和跟踪的系统和方法。 系统的变化可以包括专门的计算机系统,专用应用或基于web的服务器端解决方案。 该方法的变化可以包括基于标准和教育成功指标之间的关系以及分为进度单位的学术进度来生成综合或基于课程的教学计划。 教学计划可能会从内容存储库中填充学习和教学资源。 这样的人口可以是基于用户设置的自动化,定制的,并且可以在每个教练的基础上进行配置。 教师还可以将内容加载到存储库中,将内容与一个或多个识别参数相关联,并且基于教学风格和资源选择与每个参与者进行协作。
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