Acidic Insulin Preparations Having Improved Stability
    2.
    发明申请
    Acidic Insulin Preparations Having Improved Stability 审中-公开
    具有改善稳定性的酸性胰岛素制剂

    公开(公告)号:US20100216692A1

    公开(公告)日:2010-08-26

    申请号:US12773356

    申请日:2010-05-04

    IPC分类号: A61K38/28

    摘要: The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.

    摘要翻译: 本发明涉及包含选自胰岛素,胰岛素代谢物,胰岛素类似物,胰岛素衍生物及其组合的多肽的药物制剂; 表面活性剂或两种或更多种表面活性剂的组合; 任选的防腐剂或两种或多种防腐剂的组合; 和任选的等渗剂,缓冲剂或其它赋形剂或其组合,所述药物制剂具有在酸性范围内的pH。

    Acidic insulin preparations having improved stability
    4.
    发明授权
    Acidic insulin preparations having improved stability 有权
    具有改善的稳定性的酸性胰岛素制剂

    公开(公告)号:US07713930B2

    公开(公告)日:2010-05-11

    申请号:US12328208

    申请日:2008-12-04

    IPC分类号: A61K38/28

    摘要: The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.

    摘要翻译: 本发明涉及包含选自胰岛素,胰岛素代谢物,胰岛素类似物,胰岛素衍生物及其组合的多肽的药物制剂; 表面活性剂或两种或更多种表面活性剂的组合; 任选的防腐剂或两种或多种防腐剂的组合; 和任选的等渗剂,缓冲剂或其它赋形剂或其组合,所述药物制剂具有在酸性范围内的pH。

    Acidic insulin preparations having improved stability
    5.
    发明授权
    Acidic insulin preparations having improved stability 有权
    具有改善的稳定性的酸性胰岛素制剂

    公开(公告)号:US07476652B2

    公开(公告)日:2009-01-13

    申请号:US11089777

    申请日:2005-03-25

    IPC分类号: A61K38/28

    摘要: The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.

    摘要翻译: 本发明涉及包含选自胰岛素,胰岛素代谢物,胰岛素类似物,胰岛素衍生物及其组合的多肽的药物制剂; 表面活性剂或两种或更多种表面活性剂的组合; 任选的防腐剂或两种或多种防腐剂的组合; 和任选的等渗剂,缓冲剂或其它赋形剂或其组合,所述药物制剂具有在酸性范围内的pH。

    Acidic Insulin Preparations Having Improved Stability
    8.
    发明申请
    Acidic Insulin Preparations Having Improved Stability 有权
    具有改善稳定性的酸性胰岛素制剂

    公开(公告)号:US20090082255A1

    公开(公告)日:2009-03-26

    申请号:US12328208

    申请日:2008-12-04

    IPC分类号: A61K38/28 A61P3/10

    摘要: The invention relates to a pharmaceutical formulation comprising a polypeptide selected from the group consisting of insulin, an insulin metabolite, an insulin analog, an insulin derivative and combinations thereof; a surfactant or combinations of two or more surfactants; optionally a preservative or combinations of two or more preservatives; and optionally an isotonicizing agent, buffers or further excipients or combinations thereof, the pharmaceutical formulation having a pH in the acidic range.

    摘要翻译: 本发明涉及包含选自胰岛素,胰岛素代谢物,胰岛素类似物,胰岛素衍生物及其组合的多肽的药物制剂; 表面活性剂或两种或更多种表面活性剂的组合; 任选的防腐剂或两种或多种防腐剂的组合; 和任选的等渗剂,缓冲剂或其它赋形剂或其组合,所述药物制剂具有在酸性范围内的pH。