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公开(公告)号：US09115087B2
公开(公告)日：2015-08-25
申请号：US14242434
申请日：2014-04-01
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: C07C317/14 , C07D213/52 , C07C311/48 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D333/36 , C07D413/12 , C07D307/52
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US08329754B2
公开(公告)日：2012-12-11
申请号：US13165060
申请日：2011-06-21
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/18
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
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公开(公告)号：US08288588B2
公开(公告)日：2012-10-16
申请号：US13165048
申请日：2011-06-21
Applicant: Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: C07C311/00
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US08722925B2
公开(公告)日：2014-05-13
申请号：US13611446
申请日：2012-09-12
Applicant: Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: C07C331/00 , C07C381/00
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US20110251206A1
公开(公告)日：2011-10-13
申请号：US13165060
申请日：2011-06-21
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/4965 , C07C303/40 , A61K31/18 , C07D307/52 , C07D333/36 , C07D307/14 , C07D213/50 , A61K31/341 , A61K31/381 , A61K31/4402 , C07D333/22 , C07D241/12 , C07D231/12 , A61K31/415 , A61P29/00 , A61P11/00 , A61P35/00 , A61P3/10 , A61P17/02 , A61P19/02 , C07C311/48
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
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Patent Agency Ranking
公开(公告)号：US20110251205A1
公开(公告)日：2011-10-13
申请号：US13165048
申请日：2011-06-21
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/4965 , A61K31/341 , A61K31/381 , A61P11/00 , A61K31/4439 , A61K31/422 , A61K31/415 , A61K31/18 , A61K31/4402
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US20100029670A1
公开(公告)日：2010-02-04
申请号：US12512609
申请日：2009-07-30
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/497 , C07D307/02 , C07D333/22 , C07D241/02 , C07D211/70 , A61K31/44 , A61K31/381 , A61K31/341 , A61P35/00
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US20140213594A1
公开(公告)日：2014-07-31
申请号：US14242434
申请日：2014-04-01
Applicant: Urs BAETTIG , Anne-Marie D'SOUZA , Peter HUNT , Neil John PRESS , Simon James WATSON
Inventor： Urs BAETTIG , Anne-Marie D'SOUZA , Peter HUNT , Neil John PRESS , Simon James WATSON
IPC: C07D413/12 , C07D213/52 , C07D307/14 , C07D333/36 , C07D307/52 , C07C311/48 , C07D241/12 , C07D231/12
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US20130005735A1
公开(公告)日：2013-01-03
申请号：US13611446
申请日：2012-09-12
Applicant: Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/21 , A61K31/341 , C07C303/40 , C07C311/48 , C07D333/22 , A61K31/381 , C07D241/12 , A61K31/4965 , C07D213/50 , A61K31/4402 , C07D413/12 , A61K31/4439 , A61K31/422 , A61K31/4406 , A61K31/4409 , C07D231/12 , A61K31/415 , A61P29/00 , A61P37/08 , A61P11/00 , C07D307/52
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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公开(公告)号：US07989497B2
公开(公告)日：2011-08-02
申请号：US12512609
申请日：2009-07-30
Applicant: Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
Inventor： Urs Baettig , Anne-Marie D'Souza , Peter Hunt , Neil John Press , Simon James Watson
IPC: A61K31/18
CPC classification number: C07D213/52 , C07C311/48 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D213/38 , C07D231/12 , C07D241/12 , C07D307/14 , C07D307/42 , C07D307/52 , C07D333/36 , C07D413/12
Abstract: The present invention relates to compounds of formula (I) wherein X, R1, R2, R3, R4 and R5 are as defined herein, which are useful for treating diseases which respond to CXCR2 receptor mediators. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
Abstract translation: 本发明涉及其中X，R 1，R 2，R 3，R 4和R 5如本文所定义的式（I）化合物，其可用于治疗对CXCR2受体介体作出反应的疾病。 还描述了含有化合物的药物组合物和用于制备化合物的方法。
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