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    Polymeric biocidal salts
    1.
    发明授权
    Polymeric biocidal salts 有权
    聚合物杀生物剂

    公开(公告)号：US08926997B1

    公开(公告)日：2015-01-06

    申请号：US12798479

    申请日：2010-04-05

    申请人： Richard F. Stockel ,  Anthony J. Sawyer

    发明人： Richard F. Stockel ,  Anthony J. Sawyer

    IPC分类号： A01N25/00

    CPC分类号： A01N25/30 ,  A23B4/10 ,  A23B4/20 ,  A23L3/3481 ,  C07C57/04 ,  C07C229/26 ,  C07C279/14 ,  A01N31/08 ,  A01N31/16 ,  A01N33/12 ,  A01N37/46 ,  A01N43/38 ,  A01N43/40 ,  A01N43/50 ,  A01N47/44

    摘要： A polymeric biocidal salt is prepared from two components. The first component comprises a biocidal anionic or cationic monomeric, dendrimeric or polymeric ion. The second component comprises a dendrimeric or polymeric anion or cation having insignificant biocidal activity and a number average molecular weight of at least about 500. The second component will be cationic in nature when the first component is anionic in nature and anionic in nature when the first component is cationic in nature. The salt is further characterized as partially dissolving when exposed to an aqueous medium, thereby: (a) releasing sufficient biocidal ion to exceed the MIC or MBIC of a target bacteria sought to be controlled; and (b) leaving a reservoir of undissolved salt capable of being further dissolved and releasing additional biocidal ion as the biocidal ion is consumed or is otherwise removed from the environment encompassing the target bacteria.

    摘要翻译： 聚合物杀生物剂盐由两种组分制备。 第一组分包括杀生物阴离子或阳离子单体，树枝状或聚合离子。 第二组分包括具有不显着的杀生物活性和数均分子量至少约500的树状聚合或聚合阴离子或阳离子。当第一组分在本质上是阴离子的时，第二组分本质上是阳离子的，当第一组分本质上是阴离子时，当第一组分 组分在本​​质上是阳离子的。 盐被进一步表征为当暴露于水性介质时部分溶解，从而：（a）释放足够的杀生物离子以超过试图控制的目标细菌的MIC或MBIC; 和（b）当存在杀生物离子被消耗或者从包含目标细菌的环境中除去时，留下能溶解的未溶解的盐的储存器并释放另外的杀生物离子。

    Controlled release biocidal salts
    5.
    发明申请
    Controlled release biocidal salts 审中-公开
    控制释放的杀生物盐

    公开(公告)号：US20100173993A1

    公开(公告)日：2010-07-08

    申请号：US12658200

    申请日：2010-02-04

    申请人： Anthony J. Sawyer ,  Richard F. Stockel

    发明人： Anthony J. Sawyer ,  Richard F. Stockel

    IPC分类号： A01N37/12 ,  C07C279/14 ,  C07C229/26 ,  C07D233/64 ,  C07D209/20

    CPC分类号： A01N37/44 ,  A01N43/38 ,  A01N43/50 ,  A01N47/44 ,  A23B4/20 ,  A23L3/34635 ,  A23L3/3508 ,  A23L3/3526 ,  A23V2002/00 ,  B65D81/28 ,  Y10T428/662 ,  Y10T442/2525 ,  A01N47/14 ,  A01N43/82 ,  A01N43/40 ,  A01N37/36 ,  A01N37/02 ,  A01N33/12 ,  A01N37/06 ,  A01N37/38 ,  A01N37/40

    摘要： A controlled release biocidal salt of a first component comprises a cation of a Nα—(C1-C22)alkanoyl di-basic amino acid alkyl(C1-C22)ester cationic biocidal molecule and a second component comprising an anion of a monomeric anionic molecule having insignificant biocidal activity. The salt is characterized such that when the salt is exposed to an aqueous medium, the salt partially dissolves thereby releasing biocidal ions in an amount sufficient to exceed the MIC or MBC of a target bacteria being controlled, and further characterized as leaving a residual reservoir of undissolved salt capable of releasing more biocidal ions as the salt is consumed or otherwise removed from the environment encompassing the target bacteria. The preferred cationic biocidal molecule comprises Nα-lauroyl-L-arginine ethyl ester (“LAE”).

    摘要翻译： 第一组分的控制释放杀生物盐包含Nα-（C1-C22）烷酰基二碱性氨基酸烷基（C1-C22）酯阳离子杀生物分子的阳离子和包含单体阴离子分子的阴离子的第二组分， 不显着的杀生物活性。 盐的特征在于，当盐暴露于水性介质时，盐部分地溶解，由此释放足够超过被控制的目标细菌的MIC或MBC的量的杀生物离子，并且进一步表征为留下残留的储存器 当盐被消耗或从包围目标细菌的环境中除去时，能够释放更多杀生物离子的未溶解的盐。 优选的阳离子杀生物分子包括Nα-月桂酰-L-精氨酸乙酯（“LAE”）。