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公开(公告)号：US06948492B2
公开(公告)日：2005-09-27
申请号：US10129578
申请日：2001-08-15
申请人： Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp, Jr.
发明人： Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp, Jr.
CPC分类号： A61M15/08 , A61M11/06 , A61M15/0045 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M2205/0266 , A61M2205/073 , A61M2210/0618 , B05B11/02
摘要： An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.
摘要翻译： 一种用于自我施用多个剂量的鼻内液体药物组合物（包括阿片类镇痛药）的装置和方法，其包括含有多个密封小瓶的药物递送装置，每个小瓶含有预定体积的药物组合物， 泵组件，用于从液体药物组合物的内部输送液体药物组合物并将其作为响应于患者手动激活的鼻喷雾而排出;以及可编程装置，用于在经过规定的时间间隔后经过规定的时间间隔后续地将小瓶运送到就绪位置 最后激活传送设备。
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公开(公告)号：US07559321B2
公开(公告)日：2009-07-14
申请号：US11204611
申请日：2005-08-16
申请人： Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp
发明人： Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp
IPC分类号： A61M11/00
CPC分类号： A61M15/08 , A61M11/06 , A61M15/0045 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M2205/0266 , A61M2205/073 , A61M2210/0618 , B05B11/02
摘要： An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.
摘要翻译： 一种用于自我施用多个剂量的鼻内液体药物组合物（包括阿片类镇痛药）的装置和方法，其包括含有多个密封小瓶的药物递送装置，每个小瓶含有预定体积的药物组合物， 泵组件，用于从液体药物组合物的内部输送液体药物组合物并将其作为响应于患者手动激活的鼻喷雾而排出;以及可编程装置，用于在经过规定的时间间隔后经过规定的时间间隔后续地将小瓶运送到就绪位置 最后激活传送设备。
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公开(公告)号：US20060021614A1
公开(公告)日：2006-02-02
申请号：US11204611
申请日：2005-08-16
申请人： Daniel Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Walcott , John Main , James Lumpp
发明人： Daniel Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Walcott , John Main , James Lumpp
IPC分类号： A61M11/00
CPC分类号： A61M15/08 , A61M11/06 , A61M15/0045 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M2205/0266 , A61M2205/073 , A61M2210/0618 , B05B11/02
摘要： An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.
摘要翻译： 一种用于自我施用多个剂量的鼻内液体药物组合物（包括阿片类镇痛药）的装置和方法，其包括含有多个密封小瓶的药物递送装置，每个小瓶含有预定体积的药物组合物， 泵组件，用于从液体药物组合物的内部输送液体药物组合物并将其作为响应于患者手动激活的鼻喷雾而排出;以及可编程装置，用于在经过规定的时间间隔后经过规定的时间间隔后续地将小瓶运送到就绪位置 最后激活传送设备。
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