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公开(公告)号:US07559321B2
公开(公告)日:2009-07-14
申请号:US11204611
申请日:2005-08-16
申请人: Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp
发明人: Daniel P. Wermeling , Ryan Vallance , Aravind Balasubramaniam , Bruce Lanier Walcott , John Alan Main , James E. Lumpp
IPC分类号: A61M11/00
CPC分类号: A61M15/08 , A61M11/06 , A61M15/0045 , A61M15/008 , A61M15/0081 , A61M15/0083 , A61M2205/0266 , A61M2205/073 , A61M2210/0618 , B05B11/02
摘要: An apparatus and method for the self-administration of a plurality of doses of an intranasal liquid pharmaceutical composition, including opioid analgesics, that includes a drug delivery device containing a plurality of sealed vials, each vial containing a predetermined volume of the pharmaceutical composition, a pump assembly for conveying the liquid pharmaceutical composition from the interior of the vial and discharging it as a nasal spray in response to manual activation by the patient, and programmable means for sequentially advancing a vial to the ready position after passage of a prescribed time interval following the last activation of the delivery device.
摘要翻译: 一种用于自我施用多个剂量的鼻内液体药物组合物(包括阿片类镇痛药)的装置和方法,其包括含有多个密封小瓶的药物递送装置,每个小瓶含有预定体积的药物组合物, 泵组件,用于从液体药物组合物的内部输送液体药物组合物并将其作为响应于患者手动激活的鼻喷雾而排出;以及可编程装置,用于在经过规定的时间间隔后经过规定的时间间隔后续地将小瓶运送到就绪位置 最后激活传送设备。
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公开(公告)号:US07555900B1
公开(公告)日:2009-07-07
申请号:US10659406
申请日:2003-09-10
申请人: Robert Ryan Vallance , Bruce L. Walcott , James E. Lumpp , Aravind Balasubramanian , Osamah A. Rawashdeh
发明人: Robert Ryan Vallance , Bruce L. Walcott , James E. Lumpp , Aravind Balasubramanian , Osamah A. Rawashdeh
IPC分类号: F01B29/10
CPC分类号: F03G7/065
摘要: A linear actuator is provided, comprising a housing defining an interior channel, a stop extending from the housing and displaceable relative to the housing, and at least one wire formed of a shape-memory alloy, the wire being attached at a first end to the stop and at a second end to the housing. When heated to a predetermined temperature, the wire applies a pulling force to the stop to cause the stop to slide in a first direction into the housing interior channel. A spring located in the housing interior channel applies a biasing force to the stop in a second direction counter to the first direction when the wire cools, thereby returning the stop to the unactuated position. A wire heater is provided, which may be an electrical source for resistive heating of the wire. Multiple actuators of the present invention may be configured in parallel to increase the force generated by the wires. In yet another embodiment the actuators of the invention may be arranged in a serial configuration for controlling a rotary or carousel dispenser.
摘要翻译: 提供线性致动器,其包括限定内部通道的壳体,从壳体延伸并相对于壳体可移位的止动件以及由形状记忆合金形成的至少一根线,该线材在第一端附接到 停止并在第二端到房屋。 当加热到预定温度时,线向止动件施加拉力,使得止动件沿第一方向滑动到壳体内部通道中。 当钢丝冷却时,位于壳体内部通道中的弹簧在与第一方向相反的第二方向上向止动件施加偏压力,从而将止动件返回到未致动位置。 提供线加热器,其可以是用于电线的电阻加热的电源。 可以并行地构造本发明的多个致动器以增加由电线产生的力。 在另一个实施例中,本发明的致动器可以被布置成用于控制旋转或转盘分配器的串联配置。
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公开(公告)号:US06916115B1
公开(公告)日:2005-07-12
申请号:US10792974
申请日:2004-03-04
申请人: Robert Ryan Vallance , Bruce L. Walcott , James E. Lumpp , Sumanth Chikkamaranahalli , Osamah A. Rawashdeh , Eric Wolsing
发明人: Robert Ryan Vallance , Bruce L. Walcott , James E. Lumpp , Sumanth Chikkamaranahalli , Osamah A. Rawashdeh , Eric Wolsing
CPC分类号: G01N25/16 , G01N3/32 , G01N33/20 , G01N2203/0222 , G01N2203/0224
摘要: Instruments and methods for measuring a property of a shape memory alloy are provided. The instrument includes a base plate, a non-contact movable mass, a force gauge, an actuator, a biasing spring, a heater for heating the shape memory alloy, and a non-contact displacement detector. The biasing spring and the shape memory alloy are disposed whereby a force applied thereby is applied substantially through a center of stiffness of the movable mass. The displacement detector measures a displacement of the movable mass in a colinear direction with a direction of movement of the movable mass and with a direction of the force applied by the biasing spring and the shape memory alloy. The linear motion stage comprises a housing and at least one guide bar, and wherein a calculated axial expansion of the guide bar is substantially equal to a calculated axial expansion of the base plate.
摘要翻译: 提供了用于测量形状记忆合金的性能的仪器和方法。 该仪器包括基板,非接触可移动质量块,力量计,致动器,偏置弹簧,用于加热形状记忆合金的加热器和非接触位移检测器。 偏置弹簧和形状记忆合金被布置,由此施加的力大体上通过可移动质量块的刚度中心施加。 位移检测器测量可移动物体在共线方向上的移动与移动物体的移动方向的位移以及由偏置弹簧和形状记忆合金施加的力的方向。 线性运动台包括壳体和至少一个导杆,并且其中导引杆的计算轴向膨胀基本上等于所计算的基板的轴向膨胀。
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