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公开(公告)号:US20090203594A1
公开(公告)日:2009-08-13
申请号:US12002865
申请日:2007-12-19
摘要: A polypeptide and methods of using the polypeptide for treating malignancy by administering to a subject a composition of the polypeptide. Pharmaceutical compositions of the polypeptide.
摘要翻译: 多肽和使用该多肽治疗恶性肿瘤的方法,其通过向受试者施用该多肽的组合物。 多肽的药物组合物。
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公开(公告)号:US07456197B2
公开(公告)日:2008-11-25
申请号:US10882667
申请日:2004-07-01
申请人: Alexandru T. Balaban , William A. Seitz , Marc A. C. Ilies , Edward Bradbridge Thompson , Robert E. Garfield , Betty H. Johnson , Aaron L. Miller , Melissa J. Wentz
发明人: Alexandru T. Balaban , William A. Seitz , Marc A. C. Ilies , Edward Bradbridge Thompson , Robert E. Garfield , Betty H. Johnson , Aaron L. Miller , Melissa J. Wentz
IPC分类号: C07D401/02 , C12N15/85
CPC分类号: C07D313/20 , C12N15/87
摘要: Pyridinium cationic lipids useful as non-viral gene delivery agents are disclosed. The agents are prepared by reaction of pyrylium salts with primary amines. Also disclosed are methods of trasfectind cells using the pyridinium cationic lipids as gene transfer agents.
摘要翻译: 公开了用作非病毒基因递送剂的吡啶鎓阳离子脂质。 通过吡喃鎓盐与伯胺的反应制备试剂。 还公开了使用吡啶鎓阳离子脂质作为基因转移剂的trasfectind细胞的方法。
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公开(公告)号:US20090137045A1
公开(公告)日:2009-05-28
申请号:US12276949
申请日:2008-11-24
申请人: Alexandru T. Balaban , William A. Seitz , Marc A. C. Ilies , Edward Bradbridge Thompson , Robert E. Garfield , Betty H. Johnson , Aaron L. Miller , Melissa J. Wentz
发明人: Alexandru T. Balaban , William A. Seitz , Marc A. C. Ilies , Edward Bradbridge Thompson , Robert E. Garfield , Betty H. Johnson , Aaron L. Miller , Melissa J. Wentz
CPC分类号: C07D313/20 , C12N15/87
摘要: Pyridinium cationic lipids useful as non-viral gene delivery agents are disclosed. The agents are prepared by reaction of pyrylium salts with primary amines. Also disclosed are methods of trasfectind cells using the pyridinium cationic lipids as gene transfer agents.
摘要翻译: 公开了用作非病毒基因递送剂的吡啶鎓阳离子脂质。 通过吡喃鎓盐与伯胺的反应制备试剂。 还公开了使用吡啶鎓阳离子脂质作为基因转移剂的trasfectind细胞的方法。
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