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公开(公告)号：US20240069035A1
公开(公告)日：2024-02-29
申请号：US18261090
申请日：2022-01-12
发明人： Rajaram KRISHNAN , Robert TURNER , Juan Pablo HINESTROSA SALAZAR , Jean LEWIS , Iryna CLARK , David SEARSON
CPC分类号： G01N33/6848 , G01N1/34 , G01N33/6893
摘要： Provided herein are methods and systems for discovering biomarkers associated with risk of disease and methods using identified biomarkers for detecting disease prognosis and progression.
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公开(公告)号：US20170072395A1
公开(公告)日：2017-03-16
申请号：US15293062
申请日：2016-10-13
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David LIU
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
摘要翻译： 本发明包括用于从包含细胞的流体分离核酸的方法，装置和系统。 在各个方面，方法，装置和系统可以允许需要最少量的材料和/或产生从诸如血液或环境样品的复杂流体分离的高纯度核酸的快速程序。
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公开(公告)号：US20160046926A1
公开(公告)日：2016-02-18
申请号：US14925157
申请日：2015-10-28
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David LIU
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20150283553A1
公开(公告)日：2015-10-08
申请号：US14680819
申请日：2015-04-07
发明人： David Charlot , Juan Pablo HINESTROSA SALAZAR , Irina V. DOBROVOLSKAYA , Kai Yang , Paul SWANSON , Rajaram Krishnan
CPC分类号： B03C5/005 , B03C5/026 , B03C2201/26
摘要： The present invention includes methods, devices and systems for isolating nanoparticulates, including nucleic acids, from biological samples. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity isolation of biological components from complex fluids such as blood or environmental samples.
摘要翻译： 本发明包括从生物样品中分离纳米颗粒（包括核酸）的方法，装置和系统。 在各个方面，方法，装置和系统可以允许需要最少量的材料和/或导致生物组分与复杂流体例如血液或环境样品的高纯度分离的快速程序。
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公开(公告)号：US08932815B2
公开(公告)日：2015-01-13
申请号：US14311037
申请日：2014-06-20
发明人： Rajaram Krishnan , David J. Charlot , Eugene Tu , James McCanna , Lucas Kumosa , Paul D. Swanson , Robert Turner , Kai Yang , Irina Dobrovolskaya , David Liu , Juan Pablo Hinestrosa Salazar , Juscilene Menezes
IPC分类号： C12Q1/68 , C12N13/00 , G01N27/447
CPC分类号： C12Q1/6825 , B03C5/005 , B03C5/026 , B03C2201/18 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , C12Q1/6869 , G01N27/447
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20140248627A1
公开(公告)日：2014-09-04
申请号：US14194572
申请日：2014-02-28
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David Liu
IPC分类号： C12Q1/68
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US08815554B2
公开(公告)日：2014-08-26
申请号：US14194566
申请日：2014-02-28
发明人： Rajaram Krishnan , David Charlot , Eugene Tu , James McCanna , Lucas Kumosa , Paul Swanson , Robert Turner , Kai Yang , Irina Dobrovolskaya , David Liu
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20140183043A1
公开(公告)日：2014-07-03
申请号：US14201726
申请日：2014-03-07
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David LIU
IPC分类号： G01N27/447
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US08603791B2
公开(公告)日：2013-12-10
申请号：US13864179
申请日：2013-04-16
发明人： Rajaram Krishnan , David Charlot , Eugene Tu , James McCanna , Lucas Kumosa , Paul Swanson , Robert Turner , Kai Yang , Irina Dobrovolskaya , David Liu
IPC分类号： C12N13/00
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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公开(公告)号：US20130273640A1
公开(公告)日：2013-10-17
申请号：US13864179
申请日：2013-04-16
发明人： Rajaram KRISHNAN , David CHARLOT , Eugene TU , James MCCANNA , Lucas KUMOSA , Paul SWANSON , Robert TURNER , Kai YANG , Irina DOBROVOLSKAYA , David LIU
IPC分类号： C12N15/10
CPC分类号： B01L3/502715 , B01D57/02 , B01L7/52 , B01L2300/0636 , B01L2300/0645 , B01L2400/0424 , B03C5/005 , B03C5/026 , B03C7/023 , B03C2201/26 , C12N15/1003 , C12N15/101 , C12Q1/6806 , G01N27/447 , G01N27/44704 , G01S5/163 , G01S11/12 , G06F3/0346
摘要： The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid procedure that requires a minimal amount of material and/or results in high purity nucleic acid isolated from complex fluids such as blood or environmental samples.
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