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公开(公告)号：US12237432B2
公开(公告)日：2025-02-25
申请号：US18244767
申请日：2023-09-11
Inventor： Austin Flick , Reinhold H. Dauskardt
IPC: H01L31/0463 , B23K26/06 , B23K26/0622 , B23K26/40 , H01L31/0224 , H01L31/05 , B23K103/16
Abstract: A vertically selective liftoff scribing process is provided. One application is the fabrication of solar cells and solar modules. The basis of this technology is absorption of an indirectly focused laser beam in the front electrode material of the device, which enables removal of this layer (e.g., a P1 scribe) or removal of layers above the front electrode while leaving the front electrode intact (e.g., a P2 or P3 scribe). The laser fluence can be selected to choose between these alternatives, and further fine tuning is possible depending on details of the device structure.
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公开(公告)号：US20250062642A1
公开(公告)日：2025-02-20
申请号：US18610992
申请日：2024-03-20
Inventor： Daniel Michael Pivonka , Anatoly Anatolievich Yakovlev , Ada Shuk Yan Poon , Teresa H. Meng
IPC: H02J50/10 , A61B1/00 , A61B5/07 , A61M25/01 , A61M31/00 , H02J7/34 , H02J50/23 , H02J50/27 , H02J50/80 , H02J50/90
Abstract: Described is a locomotive implant for usage within a predetermined magnetic field. In one embodiment magnetohydrodynamics is used to generate thrust with a plurality of electrodes. In another embodiment, asymmetric drag forces are used to generate thrust.
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公开(公告)号：US12227553B2
公开(公告)日：2025-02-18
申请号：US18187639
申请日：2023-03-21
Applicant: UNIVERSITY OF WASHINGTON , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Inventor： Daniel Adriano Silva Manzano , Shawn Yu , Umut Ulge , David Baker , Kenan Christopher Garcia , Jamie Spangler , Carl Walkey
Abstract: De novo designed polypeptides that bind to IL-2 receptor βγc heterodimer (IL-2Rβγc), IL-4 receptor αγc heterodimer (IL-4Rαγc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.
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公开(公告)号：US12226892B2
公开(公告)日：2025-02-18
申请号：US18022208
申请日：2021-09-07
Inventor： Margot R. Vulliez , Oussama Khatib
Abstract: A versatile, compact, and high-fidelity haptic device is provided. The mechanical transparency of the design and the selection of proper actuation meet the challenges of an accurate and stiff haptic device with high and isotropic force capability. Such a haptic interface enables a precise remote control and provides perfect sense of the task interaction in any environments and applications.
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公开(公告)号：US20250050075A1
公开(公告)日：2025-02-13
申请号：US18233204
申请日：2023-08-11
Inventor： Kunj Raju Sheth , James K. Wall , Yair Blumenfeld , Eric Johnson , Enrico Danzer
Abstract: A medical device includes: an elongated member having a first end, a second end, and a body extending between the first end and the second end; a first anchor coupled to the first end of the elongated member; and a second anchor coupled to the second end of the elongated member; wherein the elongated member is configured for placement across an abdominal wall of a fetus, and wherein the elongated member is elastically stretchable to accommodate for a growing thickness of the abdominal wall of the fetus.
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Patent Agency Ranking
公开(公告)号：US20250049884A1
公开(公告)日：2025-02-13
申请号：US18719766
申请日：2023-01-03
Inventor： Francis Gerard Blankenberg , Derek R. Holman
IPC: A61K38/17
Abstract: Transcriptomic changes induced by uptake of extracellular vesicles (EVs) are blocked or reversed by administration of an effective dose of Annexin V protein (AnxV), e.g. by administration of AnxV to a tumor microenvironment (TME). In some embodiments, administration of AnxV is combined with a second anti-cancer therapy. In some embodiments, cells present in the TME are evaluated for transcriptional changes associated with EV uptake following administration of the effective dose of AnxV.
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公开(公告)号：US20250041487A1
公开(公告)日：2025-02-06
申请号：US18717323
申请日：2022-12-09
Inventor： Yunzhi Yang , Seyedsina Moeinzadeh
Abstract: Tissue engineering constructs and the method of making the constructs are provided. The constructs distinguish a scaffold with a surface and a treated surface area for increased surface area. A hydrophilic hydrogel network is physically cross-linked via charged polymers and salt-ions onto the treated surface area. Biologies is trapped and thereby hosted within the physically cross-linked hydrogel network. Covalently reactive macromonomers are chemically cross-linked within the physically cross-linked hydrophilic hydrogel network to strengthen the physically cross-linked hydrophilic hydrogel network itself and to the scaffold. The constructs enable delivery of therapeutics including cells and/or biomolecules along with a structural support and a defined geometry for applications in regenerative medicine.
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公开(公告)号：US12214199B2
公开(公告)日：2025-02-04
申请号：US18188120
申请日：2023-03-22
Inventor： Casey Halpern , Robert C. Malenka , Hemmings Wu
Abstract: The present invention provides, inter alia, methods, apparatus, and systems useful for ameliorating impulse control disorders known to be extremely disabling and common to many neurological and psychiatric conditions using closed-loop (responsive) neuro stimulation.
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公开(公告)号：US20250034594A1
公开(公告)日：2025-01-30
申请号：US18687090
申请日：2022-09-01
Inventor： Le Cong
IPC: C12N15/90 , C12N9/22 , C12N15/11 , C12N15/115
Abstract: The present disclosure provides recombineering-editing systems using CRISPR and recombination enzymes as well as methods, vectors, nucleic acid compositions, and kits thereof. The methods and systems provide means for altering target DNA, including genomic DNA in a host cell.
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公开(公告)号：US20250027162A1
公开(公告)日：2025-01-23
申请号：US18289455
申请日：2022-05-09
Inventor： Srividya SWAMINATHAN , Holden Maecker , Anil Kumar , Caroline Duault , Adeleh Taghi Khani
IPC: C12Q1/6886 , G01N33/569 , G01N33/574
Abstract: Provided herein are, inter alia, methods for identifying dysfunctional natural killer (NK) cells in a subject with leukemia. Provided are methods for treating leukemia, including administering to the subject an effective amount of allogeneic NK cells.
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