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公开(公告)号：US08143305B2
公开(公告)日：2012-03-27
申请号：US12675897
申请日：2008-08-27
申请人： Gopinadhan N. Anilkumar , Frank Bennett , Tin-Yau Chan , Kevin X. Chen , Mousumi Sannigrahi , Francisco Velazquez , Srikanth Venkatraman , Qingbei Zeng , Jose S. Duca , Charles A. Lesburg , Joseph A. Kozlowski , F. George Njoroge , Stuart B. Rosenblum , Neng-Yang Shih , Stephen J. Gavalas , Yueheng Jiang , Patrick A. Pinto , Haiyan Pu , Oleg B. Selyutin , Bancha Vibulbhan , Li Wang , Wanli Wu , Weiying Yang , Yuhua Huang , Hsueh-Cheng Huang , Robert Palermo , Boris Feld
发明人： Gopinadhan N. Anilkumar , Frank Bennett , Tin-Yau Chan , Kevin X. Chen , Mousumi Sannigrahi , Francisco Velazquez , Srikanth Venkatraman , Qingbei Zeng , Jose S. Duca , Charles A. Lesburg , Joseph A. Kozlowski , F. George Njoroge , Stuart B. Rosenblum , Neng-Yang Shih , Stephen J. Gavalas , Yueheng Jiang , Patrick A. Pinto , Haiyan Pu , Oleg B. Selyutin , Bancha Vibulbhan , Li Wang , Wanli Wu , Weiying Yang , Yuhua Huang , Hsueh-Cheng Huang , Robert Palermo , Boris Feld
IPC分类号： A01N43/38 , A61K31/40 , C07D209/04
CPC分类号： C07D417/14 , C07D209/42 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention relates to 2,3-Substituted Indole Derivatives, compositions comprising at least one 2,3-Substituted Indole Derivative, and methods of using the 2,3-Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.
摘要翻译： 本发明涉及2,3-取代的吲哚衍生物，包含至少一种2,3-取代的吲哚衍生物的组合物和使用2,3-取代的吲哚衍生物用于治疗或预防病毒感染或病毒相关的方法 病人无序。
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公开(公告)号：US20090209483A1
公开(公告)日：2009-08-20
申请号：US12412967
申请日：2009-03-27
申请人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
发明人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
IPC分类号： A61K31/7068
CPC分类号： A61K31/7072 , A61K38/212 , A61K2300/00
摘要： The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
摘要翻译： 本发明提供了在宿主中通过属于黄病毒科的病毒如HCV的感染的方法，其包括向宿主施用Ara-C同源物。
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公开(公告)号：US07816339B2
公开(公告)日：2010-10-19
申请号：US12412967
申请日：2009-03-27
申请人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
发明人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
CPC分类号： A61K31/7072 , A61K38/212 , A61K2300/00
摘要： The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
摘要翻译： 本发明提供了在宿主中通过属于黄病毒科的病毒如HCV的感染的方法，其包括向宿主施用Ara-C同源物。
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公开(公告)号：US20110033417A1
公开(公告)日：2011-02-10
申请号：US12675897
申请日：2008-08-27
申请人： Gopinadhan N. Anilkumar , Frank Bennett , Tin-Yau Chan , Kevin X. Chen , Mousumi Sannigrahi , Francisco Velazquez , Srikanth Venkatraman , Qingbei Zeng , Jose S. Duca , Charles A. Lesburg , Joseph A. Kozlowski , F. George Njoroge , Stuart B. Rosenblum , Neng-Yang Shih , Stephen J. Gavalas , Yueheng Jiang , Patrick A. Pinto , Haiyan Pu , Oleg B. Selyutin , Bancha Vibulbhan , Li Wang , Wanli Wu , Weiying Yang , Yuhua Huang , Hsueh-Cheng Huang , Robert Palermo , Boris Feld
发明人： Gopinadhan N. Anilkumar , Frank Bennett , Tin-Yau Chan , Kevin X. Chen , Mousumi Sannigrahi , Francisco Velazquez , Srikanth Venkatraman , Qingbei Zeng , Jose S. Duca , Charles A. Lesburg , Joseph A. Kozlowski , F. George Njoroge , Stuart B. Rosenblum , Neng-Yang Shih , Stephen J. Gavalas , Yueheng Jiang , Patrick A. Pinto , Haiyan Pu , Oleg B. Selyutin , Bancha Vibulbhan , Li Wang , Wanli Wu , Weiying Yang , Yuhua Huang , Hsueh-Cheng Huang , Robert Palermo , Boris Feld
IPC分类号： A61K38/21 , C07D401/04 , C07D413/14 , C07D209/42 , C07D401/14 , C07D417/14 , C07D407/14 , C07D409/14 , A61K31/4439 , A61K31/444 , A61K31/404 , A61K31/4545 , A61K31/513 , A61K31/443 , A61K31/4709 , A61K31/4436 , A61K31/5377 , A61K31/538 , A61K31/5415 , A61K31/7088 , A61K31/7052 , A61K39/12 , A61K39/42 , A61P31/12 , A61P31/14
CPC分类号： C07D417/14 , C07D209/42 , C07D401/04 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14
摘要： The present invention relates to 2,3-Substituted Indole Derivatives, compositions comprising at least one 2,3-Substituted Indole Derivative, and methods of using the 2,3-Substituted Indole Derivatives for treating or preventing a viral infection or a virus-related disorder in a patient.
摘要翻译： 本发明涉及2,3-取代的吲哚衍生物，包含至少一种2,3-取代的吲哚衍生物的组合物和使用2,3-取代的吲哚衍生物用于治疗或预防病毒感染或病毒相关的方法 病人无序。
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公开(公告)号：US07524831B2
公开(公告)日：2009-04-28
申请号：US11365008
申请日：2006-03-01
申请人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
发明人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
CPC分类号： A61K31/7072 , A61K38/212 , A61K2300/00
摘要： The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
摘要翻译： 本发明提供了在宿主中通过属于黄病毒科的病毒如HCV的感染的方法，其包括向宿主施用Ara-C同源物。
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公开(公告)号：US20060198824A1
公开(公告)日：2006-09-07
申请号：US11365008
申请日：2006-03-01
申请人： Bruce Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
发明人： Bruce Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
IPC分类号： A61K31/7072 , A61K38/21
CPC分类号： A61K31/7072 , A61K38/212 , A61K2300/00
摘要： The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
摘要翻译： 本发明提供了在宿主中通过属于黄病毒科的病毒如HCV的感染的方法，其包括向宿主施用Ara-C同源物。
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公开(公告)号：US20110033422A1
公开(公告)日：2011-02-10
申请号：US12906651
申请日：2010-10-18
申请人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
发明人： Bruce A. Malcolm , Robert Palermo , Xiao Tong , Boris Feld , Hung Le
IPC分类号： A61K38/21 , A61K31/7068 , A61P31/12
CPC分类号： A61K31/7072 , A61K38/212 , A61K2300/00
摘要： The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
摘要翻译： 本发明提供了在宿主中通过属于黄病毒科的病毒如HCV的感染的方法，其包括向宿主施用Ara-C同源物。
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