公开(公告)号：US20070106197A1

公开(公告)日：2007-05-10

申请号：US11616204

申请日：2006-12-26

申请人： Brian Lauman ,  John Parish

发明人： Brian Lauman ,  John Parish

IPC分类号： A61M37/00 ,  A61M1/00 ,  A61F7/00

CPC分类号： F24H1/121 ,  A61M1/1656 ,  A61M1/166 ,  A61M1/1668 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M5/44 ,  A61M2205/127 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2205/3686 ,  H05B3/0085

摘要： A method of structuring a machine to heat a dialysis fluid includes: (i) allowing flow of the dialysis fluid through a disposable fluid conduit; (ii) directing energy from a 2-dimensional energy source to apply energy to the dialysis fluid in the disposable fluid conduit; and (iii) directing energy from a 3-dimensional energy source to apply energy to the dialysis fluid in the disposable fluid conduit.

摘要翻译： 构造机器以加热透析流体的方法包括：（i）允许透析流体流过一次性流体导管; （ii）引导来自二维能源的能量以将能量施加到所述一次性流体导管中的透析流体; 和（iii）从三维能量源引导能量以将能量施加到一次性流体导管中的透析流体。

公开(公告)号：US07153286B2

公开(公告)日：2006-12-26

申请号：US10155603

申请日：2002-05-24

申请人： Don Busby ,  Peter Hopping ,  Robert Childers ,  Shahid Din ,  Brian Lauman ,  Rick Kienman ,  Ian Richardson ,  Joseph H. Bowman, Jr. ,  Loren M. Lundtveit ,  Jose Alvaro ,  Bruce Ming-Da Eu ,  Sherwin Shang

发明人： Don Busby ,  Peter Hopping ,  Robert Childers ,  Shahid Din ,  Brian Lauman ,  Rick Kienman ,  Ian Richardson ,  Joseph H. Bowman, Jr. ,  Loren M. Lundtveit ,  Jose Alvaro ,  Bruce Ming-Da Eu ,  Sherwin Shang

IPC分类号： A31M37/00 ,  C02F1/33 ,  A61M1/36

CPC分类号： A61M1/267 ,  A61M1/166 ,  A61M1/28 ,  A61M1/281 ,  A61M1/288 ,  A61M2205/127 ,  A61M2205/50 ,  A61M2205/581 ,  A61M2205/583 ,  G06F19/00

摘要： The present invention provides automated peritoneal dialysis systems, methods of operating the systems and devices for performing same. A typical therapy performed by the present invention begins by draining dialysis solution that is already in the patient's peritoneal cavity. The system pumps fresh dialysate from one of a plurality of supply bags, through an in-line heater to the patient's peritoneal cavity. After a dwell period, the spent dialysate in the cavity is pumped out of the patient to a drain or other disposal means. The system then pumps fresh dialysate from the supply bags to the patient and the procedure is repeated as defined in the therapy protocol. The system can pump a last bag of dialysate to the peritoneal cavity for an extended dwell, such as a daytime dwell.

公开(公告)号：US20120179133A1

公开(公告)日：2012-07-12

申请号：US13423886

申请日：2012-03-19

申请人： John Bedingfield ,  Brian Lauman

发明人： John Bedingfield ,  Brian Lauman

IPC分类号： A61M1/14

CPC分类号： F24H9/2028 ,  A61M1/166 ,  A61M1/28 ,  A61M1/282 ,  A61M5/445 ,  A61M2205/3653 ,  F24H1/101

摘要： A method for heating medical fluid with different supply voltages comprising: configuring first, second and third switches in electrical communication with first and second power lines, the switches configured such that (i) in a first switch state first and second heater elements are placed in series, solely via a closing of the first switch, for operation with a first supply voltage applied to the first and second power lines, and (ii) in a second switch state the first and second heater elements are placed in parallel, via the second and third switches, for operation with a second supply voltage applied to the first and second power lines, and configuring a control element to automatically set the switches in the first or the second switch state based upon a signal sent to the control element indicative of the first or the second supply voltage.

摘要翻译： 一种用于加热具有不同电源电压的医用流体的方法，包括：配置与第一和第二电力线电连通的第一，第二和第三开关，所述开关被配置为使得（i）在第一开关状态中将第一和第二加热器元件置于 系列，仅通过关闭第一开关，用于施加到第一和第二电力线的第一电源电压的操作，以及（ii）在第二开关状态下，第一和第二加热器元件经由第二开关 以及第三开关，用于以施加到第一和第二电力线的第二电源电压进行操作，以及配置控制元件，以基于发送到控制元件的信号自动地将开关设置在第一或第二开关状态， 第一或第二电源电压。

公开(公告)号：US20110288480A1

公开(公告)日：2011-11-24

申请号：US13198154

申请日：2011-08-04

申请人： John Bedingfield ,  Brian Lauman

发明人： John Bedingfield ,  Brian Lauman

IPC分类号： A61M5/44

CPC分类号： F24H9/2028 ,  A61M1/166 ,  A61M1/28 ,  A61M1/282 ,  A61M5/445 ,  A61M2205/3653 ,  F24H1/101

摘要： A medical fluid heating system operable with different supply voltages including first and second heater elements: first and second power lines, first, second and third switches in electrical communication with the first and second power lines, the switches configured such that (i) in a first switch state the first and second heater elements are placed in series, solely via a closing of the first switch, for operation with a first supply voltage applied to the first and second power lines, and (ii) in a second switch state the first and second heater elements are placed in parallel, via the second and third switches, for operation with a second supply voltage applied to the first and second power lines, and a control element configured to automatically set the switches in the first or the second switch state based upon a signal sent to the control element indicative of the first or the second supply voltage.

摘要翻译： 一种医疗流体加热系统，其可操作的不同的电源电压包括第一和第二加热器元件：与第一和第二电力线电连通的第一和第二电力线，第一，第二和第三开关，所述开关被配置为使得（i） 第一开关状态，第一和第二加热器元件仅通过第一开关的闭合而串联放置，用于施加到第一和第二电力线的第一电源电压的操作，以及（ii）在第二开关状态下，第一开关状态 并且第二加热器元件经由第二和第三开关并联放置，以施加到第一和第二电力线的第二电源电压进行操作;以及控制元件，被配置为将开关自动设置在第一或第二开关状态 基于发送到指示第一或第二电源电压的控制元件的信号。

公开(公告)号：US07458951B2

公开(公告)日：2008-12-02

申请号：US11616204

申请日：2006-12-26

申请人： Brian Lauman ,  John Parish

发明人： Brian Lauman ,  John Parish

IPC分类号： A61M37/00 ,  A61F7/00

CPC分类号： F24H1/121 ,  A61M1/1656 ,  A61M1/166 ,  A61M1/1668 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M5/44 ,  A61M2205/127 ,  A61M2205/3653 ,  A61M2205/368 ,  A61M2205/3686 ,  H05B3/0085

摘要： A method of structuring a machine to heat a dialysis fluid includes: (i) allowing flow of the dialysis fluid through a disposable fluid conduit; (ii) directing energy from a 2-dimensional energy source to apply energy to the dialysis fluid in the disposable fluid conduit; and (iii) directing energy from a 3-dimensional energy source to apply energy to the dialysis fluid in the disposable fluid conduit.

摘要翻译： 构造机器以加热透析流体的方法包括：（i）允许透析流体流过一次性流体导管; （ii）引导来自二维能源的能量以将能量施加到所述一次性流体导管中的透析流体; 和（iii）从三维能量源引导能量以将能量施加到一次性流体导管中的透析流体。

公开(公告)号：US20080021377A1

公开(公告)日：2008-01-24

申请号：US11773903

申请日：2007-07-05

申请人： Richard Kienman ,  Dan Roush ,  John Steck ,  James Slepicka ,  Atif Yardimci ,  Gideon Hecht ,  Jennifer Lindsay ,  George Bobart ,  Donald Busby ,  William Chan ,  Yuanpang Ding ,  Amy Twining ,  Douglas Reitz ,  Andrey Kopychev ,  Mehmet Ozer ,  Brian Lauman

发明人： Richard Kienman ,  Dan Roush ,  John Steck ,  James Slepicka ,  Atif Yardimci ,  Gideon Hecht ,  Jennifer Lindsay ,  George Bobart ,  Donald Busby ,  William Chan ,  Yuanpang Ding ,  Amy Twining ,  Douglas Reitz ,  Andrey Kopychev ,  Mehmet Ozer ,  Brian Lauman

IPC分类号： A61M1/28

CPC分类号： A61M5/44 ,  A61M1/1635 ,  A61M1/1696 ,  A61M1/342 ,  A61M1/3434 ,  A61M1/3437 ,  A61M1/3458 ,  A61M2205/127

摘要： A dialysis fluid heating system includes a plurality of conductive tubes; first and second end caps located at first and second ends of the tubes, respectively, the first end cap including a dialysis fluid inlet and a dialysis fluid outlet, the end caps and the tubes configured such that dialysis fluid can flow from the fluid inlet of the first end cap, through at least one first tube to the second end cap, and through at least one second tube back to the first end cap; a conductive wire wound around an outside of the conductive tubes; and electronics configured to supply power to the conductive wire, the wire forming a primary coil of a transformer, the tubes forming a secondary coil of the transformer.

摘要翻译： 透析液加热系统包括多个导电管; 分别位于管的第一和第二端处的第一和第二端盖，第一端盖包括透析流体入口和透析流体出口，端盖和管构造成使得透析流体可以从 所述第一端盖通过至少一个第一管至所述第二端盖，并且穿过至少一个第二管回到所述第一端盖; 缠绕在导电管外侧的导线; 以及电子器件，被配置为向所述导线提供电力，所述线形成变压器的初级线圈，所述管形成所述变压器的次级线圈。

公开(公告)号：US08206338B2

公开(公告)日：2012-06-26

申请号：US11773148

申请日：2007-07-03

申请人： Robert W. Childers ,  Brian Lauman

发明人： Robert W. Childers ,  Brian Lauman

IPC分类号： A61M1/00

CPC分类号： A61M1/281 ,  A61M1/16 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M2205/122

摘要： A peritoneal dialysis system includes a dialysis machine including a pump chamber and a pump actuator moveable within the pump chamber; a pumping cassette including a rigid portion defining a pump well and a flexible membrane covering the pump well; and wherein the dialysis machine is configured to be mated with the pumping cassette so as to hold a vacuum between the pump chamber and the flexible membrane, the vacuum operable to cause the flexible membrane to follow the pump actuator as the actuator is retracted from the pump well of the rigid portion, the pump actuator operable to cause the flexible membrane to move into the pump well as the actuator is moved into the pump well.

摘要翻译： 腹膜透析系统包括透析机，其包括泵室和在泵室内可移动的泵致动器; 泵壳，包括限定泵井的刚性部分和覆盖泵井的柔性膜; 并且其中所述透析机配置为与所述泵送盒配合以便在所述泵室和所述柔性膜之间保持真空，所述真空可操作以使得所述柔性膜随着所述致动器从所述泵缩回而跟随所述泵致动器 在致动器移动到泵井中时，泵致动器可操作以使柔性膜移动到泵井中。

公开(公告)号：US20110144570A1

公开(公告)日：2011-06-16

申请号：US13033126

申请日：2011-02-23

申请人： Robert W. Childers ,  Lee Pan ,  Brian Lauman

发明人： Robert W. Childers ,  Lee Pan ,  Brian Lauman

IPC分类号： A61M1/28

CPC分类号： A61M1/28 ,  A61M1/166 ,  A61M1/1696 ,  A61M1/281 ,  A61M1/284 ,  G06F19/00

摘要： Systems and methods for providing multiple pass continuous flow dialysis therapy are provided. The present invention includes a fluid circuit connected to a patient via a catheter thereby defining a fluid loop along which a therapy fluid including a dialysate can be continuously circulated into, through and out of a peritoneal cavity of a patient to remove a therapeutically effective amount of excess water and solutes including uremic toxins. The feed rate and discharge rate of therapy fluid into the fluid loop can be controllably regulated in proportion to the circulation rate of fluid in the fluid loop such that the therapy fluid can pass a multiple number of times along the fluid loop prior to discharge.

摘要翻译： 提供了用于提供多次连续流量透析治疗的系统和方法。 本发明包括通过导管连接到患者的流体回路，从而限定了流体回路，包括透析液的治疗流体沿着该流体回路可以连续地循环到患者的腹膜腔内并从腹膜腔中除去治疗有效量的 过量的水和溶质包括尿毒症毒素。 治疗流体进入流体回路的进料速率和排出速率可以与流体回路中流体的循环速度成比例地可控制地调节，使得治疗流体可以在排出之前沿流体回路多次通过。

公开(公告)号：US20110106003A1

公开(公告)日：2011-05-05

申请号：US12987738

申请日：2011-01-10

申请人： Robert W. Childers ,  Richard Avoy ,  John Booras ,  Joseph H. Bowman, JR. ,  Paul Grippo ,  Andrew D. Hopping ,  David Howard ,  Jeffrey W. Jerrell ,  Benjamin Kellam ,  Brian Lauman ,  Sherwin Shang ,  David Vescovi ,  Tahua Yang ,  Alex Yu

发明人： Robert W. Childers ,  Richard Avoy ,  John Booras ,  Joseph H. Bowman, JR. ,  Paul Grippo ,  Andrew D. Hopping ,  David Howard ,  Jeffrey W. Jerrell ,  Benjamin Kellam ,  Brian Lauman ,  Sherwin Shang ,  David Vescovi ,  Tahua Yang ,  Alex Yu

IPC分类号： A61M1/28

CPC分类号： A61M1/281 ,  A61M1/16 ,  A61M1/1696 ,  A61M1/28 ,  A61M1/284 ,  A61M2205/122

摘要： A peritoneal dialysis system includes a disposable cassette including a flexible sheet; a hardware unit including (i) at least one pump actuator and piston head moved by the pump actuator, (ii) at least one valve actuator, (iii) at least one sensor, and (iv) a disposable cassette interface for interfacing with the disposable cassette, the disposable cassette interface including: (a) at least one pump aperture, the at least one piston head moveable out of and retractable into the at least one pump aperture to move a corresponding pumping portion of the flexible sheet of the disposable cassette, the piston head moving within a vacuum chamber, the vacuum chamber enabling a vacuum to be pulled around the piston head to the flexible sheet of the disposable cassette; (b) at least one valve aperture, at least a portion of the at least one valve actuator located in the valve aperture to move a valve portion of the flexible sheet of the disposable cassette; and (c) at least one sensor aperture, the at least one sensor located in the at least one sensor aperture, the at least one sensor operable with a sensor portion of the flexible sheet of the disposable cassette.

摘要翻译： 腹膜透析系统包括：包括柔性片的一次性盒; 硬件单元包括（i）由泵致动器移动的至少一个泵致动器和活塞头，（ii）至少一个阀致动器，（iii）至少一个传感器，以及（iv）一次性盒接口，用于与 所述一次性盒式接口包括：（a）至少一个泵孔，所述至少一个活塞头可移动到所述至少一个泵孔中并可缩回到所述至少一个泵孔中，以移动所述一次性盒的柔性片的相应的泵送部分 所述活塞头在真空室内移动，所述真空室能够使所述活塞头周围的真空被拉到所述一次性盒的柔性片; （b）至少一个阀孔，所述至少一个阀致动器的至少一部分位于阀孔中，以移动一次性盒的柔性片的阀部分; 和（c）至少一个传感器孔，所述至少一个传感器位于所述至少一个传感器孔中，所述至少一个传感器可与一次性盒的柔性片的传感器部分一起操作。

公开(公告)号：US07922686B2

公开(公告)日：2011-04-12

申请号：US10624150

申请日：2003-07-17

申请人： Robert W. Childers ,  Lee Pan ,  Brian Lauman

发明人： Robert W. Childers ,  Lee Pan ,  Brian Lauman

IPC分类号： A61M1/00

CPC分类号： A61M1/28 ,  A61M1/166 ,  A61M1/1696 ,  A61M1/281 ,  A61M1/284 ,  G06F19/00

摘要： Systems and methods for providing multiple pass continuous flow dialysis therapy are provided. The present invention includes a fluid circuit connected to a patient via a catheter thereby defining a fluid loop along which a therapy fluid including a dialysate can be continuously circulated into, through and out of a peritoneal cavity of a patient to remove a therapeutically effective amount of excess water and solutes including uremic toxins. The feed rate and discharge rate of therapy fluid into the fluid loop can be controllably regulated in proportion to the circulation rate of fluid in the fluid loop such that the therapy fluid can pass a multiple number of times along the fluid loop prior to discharge.

摘要翻译： 提供了用于提供多次连续流量透析治疗的系统和方法。 本发明包括通过导管连接到患者的流体回路，从而限定了流体回路，包括透析液的治疗流体沿着该流体回路可以连续地循环到患者的腹膜腔内并从腹膜腔中除去治疗有效量的 过量的水和溶质包括尿毒症毒素。 治疗流体进入流体回路的进料速率和排出速率可以与流体回路中流体的循环速度成比例地可控制地调节，使得治疗流体可以在排出之前沿流体回路多次通过。