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公开(公告)号：US08071605B2
公开(公告)日：2011-12-06
申请号：US12634809
申请日：2009-12-10
申请人： Gregory Basarab , Pamela Hill , Brian Sherer , Fei Zhou
发明人： Gregory Basarab , Pamela Hill , Brian Sherer , Fei Zhou
IPC分类号： A61K31/4965 , A61K31/425
CPC分类号： C07D417/14 , C07D487/08
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US20100173909A1
公开(公告)日：2010-07-08
申请号：US12634809
申请日：2009-12-10
申请人： Gregory BASARAB , Pamela HILL , Brian SHERER , Fei ZHOU
发明人： Gregory BASARAB , Pamela HILL , Brian SHERER , Fei ZHOU
IPC分类号： A61K31/454 , C07D401/14 , A61K31/497 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61P31/04
CPC分类号： C07D417/14 , C07D487/08
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US20080161306A1
公开(公告)日：2008-07-03
申请号：US11816450
申请日：2006-02-16
申请人： Brian Sherer , Fei Zhou
发明人： Brian Sherer , Fei Zhou
IPC分类号： A61K31/5377 , C07D207/36 , A61K31/40 , C07D413/02
CPC分类号： C07D207/34
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described: Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 还描述了式（I）化合物及其药学上可接受的盐：其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US20100190745A1
公开(公告)日：2010-07-29
申请号：US12477781
申请日：2009-06-03
IPC分类号： A61K31/695 , C07D215/20 , A61K31/4709 , C07D498/02 , A61K31/5383 , A61K31/397 , C07D401/14 , A61K31/496 , C07D413/14 , A61K31/5377 , C07F7/02 , A61P31/04
CPC分类号： C07D417/14 , C07D498/06
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US20100179150A1
公开(公告)日：2010-07-15
申请号：US11816612
申请日：2006-02-16
申请人： Gregory Basarab , Brian Dangel , Paul Robert Fleming , Michael Barry Gravestock , Oluyinka Green , Sheila Irene Hauck , Pamela Hill , Kenneth Gregory Hull , George Mullen , Brian Sherer , Fei Zhou , Haihong Ni
发明人： Gregory Basarab , Brian Dangel , Paul Robert Fleming , Michael Barry Gravestock , Oluyinka Green , Sheila Irene Hauck , Pamela Hill , Kenneth Gregory Hull , George Mullen , Brian Sherer , Fei Zhou , Haihong Ni
IPC分类号： A61K31/454 , C07D417/14 , C07D401/14 , A61K31/5377 , A61K31/4545 , A61P31/04
CPC分类号： C07D417/14 , C07D401/14 , C07D513/04
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US08399489B2
公开(公告)日：2013-03-19
申请号：US11816612
申请日：2006-02-16
申请人： Gregory Basarab , Brian Dangel , Paul Robert Fleming , Michael Barry Gravestock , Oluyinka Green , Sheila Irene Hauck , Pamela Hill , Kenneth Gregory Hull , George Mullen , Haihong Ni , Brian Sherer , Fei Zhou
发明人： Gregory Basarab , Brian Dangel , Paul Robert Fleming , Michael Barry Gravestock , Oluyinka Green , Sheila Irene Hauck , Pamela Hill , Kenneth Gregory Hull , George Mullen , Haihong Ni , Brian Sherer , Fei Zhou
IPC分类号： A61K31/454 , C07D401/14
CPC分类号： C07D417/14 , C07D401/14 , C07D513/04
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US08283361B2
公开(公告)日：2012-10-09
申请号：US12477781
申请日：2009-06-03
IPC分类号： A61K31/04 , C07D215/38
CPC分类号： C07D417/14 , C07D498/06
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US20120101100A1
公开(公告)日：2012-04-26
申请号：US12392730
申请日：2009-02-25
申请人： Shanta Bist , Brian Dangel , Brian Sherer
发明人： Shanta Bist , Brian Dangel , Brian Sherer
IPC分类号： A61K31/5377 , A61K31/444 , A61P31/04 , A61K31/5025 , C07D413/14 , C07D401/14 , C07D487/04
CPC分类号： C07D417/14 , C07D413/14
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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9.发明申请2-(PIPERIDIN-1-YL)-4-HETEROCYCLYL-THIAZOLE-5-CARBOXYLIC ACID DERIVATIVES AGAINST BACTERIAL INFECTIONS 审中-公开2-（哌啶-1-基）-4-环烷基 - 噻唑-5-羧酸衍生物对细菌感染公开(公告)号：US20120028979A1
公开(公告)日：2012-02-02
申请号：US13267271
申请日：2011-10-06
申请人： Gregory BASARAB , Pamela HILL , Brian SHERER , Fei ZHOU
发明人： Gregory BASARAB , Pamela HILL , Brian SHERER , Fei ZHOU
IPC分类号： A61K31/454 , A61K31/4545 , A61K31/497 , A61P31/04 , A61K31/4995 , A61K31/506 , C07D413/14 , A61K31/5377 , C07D417/14 , C07D487/08
CPC分类号： C07D417/14 , C07D487/08
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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公开(公告)号：US07674801B2
公开(公告)日：2010-03-09
申请号：US11950105
申请日：2007-12-04
IPC分类号： C07D471/04
CPC分类号： C07D417/04 , C07D213/75 , C07D213/80 , C07D213/82 , C07D239/42 , C07D277/48 , C07D401/04 , C07D417/14 , C07D471/04
摘要： Compounds of formula (I) and their pharmaceutically acceptable salts are described. Processes for their preparation, pharmaceutical compositions containing them, their use as medicaments and their use in the treatment of bacterial infections are also described.
摘要翻译： 描述式（I）化合物及其药学上可接受的盐。 还描述了其制备方法，含有它们的药物组合物，其作为药物的用途及其在治疗细菌感染中的用途。
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