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公开(公告)号:US20130289687A1
公开(公告)日:2013-10-31
申请号:US13997939
申请日:2011-12-28
申请人: Tal Dvir , Daniel S. Kohane , Robert S. Langer , Brian Timko
发明人: Tal Dvir , Daniel S. Kohane , Robert S. Langer , Brian Timko
CPC分类号: A61F2/2418 , A61L27/3826 , A61L27/44 , A61L27/446 , A61L27/54 , A61L2400/12 , A61N1/0597 , B82Y5/00 , Y10S977/762
摘要: Electrically conductive nanowires incorporated within scaffolds enhance tissue growth, bridge the electrically resistant pore walls and markedly improve electrical communication between adjacent cardiac cell bundles. Integration of conducting nanowires within 3D scaffolds should improve the therapeutic value of cardiac patches. Examples demonstrate efficacy of gold nanowires in alginate matrices seeded with cardiomyocytes.
摘要翻译: 掺入支架内的导电纳米线增强组织生长,桥接电阻孔壁并显着改善相邻心肌细胞束之间的电连通。 导管纳米线在3D支架内的整合应提高心脏贴片的治疗价值。 实施例证明金纳米线在与心肌细胞接种的藻酸盐基质中的功效。
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公开(公告)号:US09114009B2
公开(公告)日:2015-08-25
申请号:US13997939
申请日:2011-12-28
申请人: Tal Dvir , Daniel S. Kohane , Robert S. Langer , Brian Timko
发明人: Tal Dvir , Daniel S. Kohane , Robert S. Langer , Brian Timko
CPC分类号: A61F2/2418 , A61L27/3826 , A61L27/44 , A61L27/446 , A61L27/54 , A61L2400/12 , A61N1/0597 , B82Y5/00 , Y10S977/762
摘要: Electrically conductive nanowires incorporated within scaffolds enhance tissue growth, bridge the electrically resistant pore walls and markedly improve electrical communication between adjacent cardiac cell bundles. Integration of conducting nanowires within 3D scaffolds should improve the therapeutic value of cardiac patches. Examples demonstrate efficacy of gold nanowires in alginate matrices seeded with cardiomyocytes.
摘要翻译: 掺入支架内的导电纳米线增强组织生长,桥接电阻孔壁并显着改善相邻心肌细胞束之间的电连通。 导管纳米线在3D支架内的整合应提高心脏贴片的治疗价值。 实施例证明金纳米线在与心肌细胞接种的藻酸盐基质中的功效。
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