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    Oxidation-sensitive hydrophilic active principle containing composition and use thereof
    1.
    发明授权
    Oxidation-sensitive hydrophilic active principle containing composition and use thereof 有权
    含氧化物的亲水性活性成分及其用途

    公开(公告)号：US07691903B2

    公开(公告)日：2010-04-06

    申请号：US10463656

    申请日：2003-06-18

    申请人： Bruno Biatry

    发明人： Bruno Biatry

    IPC分类号： A61K31/34 ,  A61K47/00 ,  A61K31/00 ,  A61K31/765 ,  A61K9/28 ,  A61K9/14 ,  A01N43/08

    CPC分类号： A61K8/11 ,  A61K8/347 ,  A61K8/4973 ,  A61K8/676 ,  A61K8/8164 ,  A61K8/8182 ,  A61K2800/412 ,  A61K2800/52 ,  A61K2800/522 ,  A61Q5/08 ,  A61Q17/00 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/007 ,  A61Q19/02 ,  A61Q19/08

    摘要： The invention relates to a composition for topical use containing at least one oxidation sensitive hydrophilic active principle and at least one maleic anhydride copolymer, comprising one or more maleic anhydride comonomers and one or more comonomers selected from the group consisting of vinyl acetate, vinyl alcohol, vinylpyrrolidone, olefins containing from 2 to 20 carbon atoms, and styrene, in a physiologically acceptable medium containing an aqueous phase. The invention also relates to the use of a maleic anhydride copolymer as defined above for stabilizing an oxidation-sensitive hydrophilic active principle, in particular in the aqueous phase.

    摘要翻译： 本发明涉及包含至少一种氧化敏感性亲水性活性成分和至少一种马来酸酐共聚物的局部用组合物，其包含一种或多种马来酸酐共聚单体和一种或多种共聚单体，所述共聚单体选自乙酸乙烯酯，乙烯醇， 乙烯基吡咯烷酮，含有2-20个碳原子的烯
    烃和苯乙烯，在含水相的生理学上可接受的介质中。 本发明还涉及如上定义的马来酸酐共聚物用于稳定氧化敏感的亲水性活性成分，特别是在水相中的用途。

    Gelled oil particles comprising at least one hydrophobic sunscreen
    2.
    发明申请
    Gelled oil particles comprising at least one hydrophobic sunscreen 审中-公开
    包含至少一种疏水防晒剂的凝胶油颗粒

    公开(公告)号：US20060292095A1

    公开(公告)日：2006-12-28

    申请号：US11434731

    申请日：2006-05-17

    申请人： Bruno Biatry ,  Jean-Thierry Simonnet

    发明人： Bruno Biatry ,  Jean-Thierry Simonnet

    IPC分类号： A61K8/81 ,  A61K8/73

    CPC分类号： A61K8/585 ,  A61K8/042 ,  A61K8/37 ,  A61K8/40 ,  A61K8/8117 ,  A61K8/88 ,  A61K8/891 ,  A61Q17/04

    摘要： The present invention relates to calibrated oily particles comprising at least one hydrophobic sunscreen and comprising at least one oily phase structured with at least one gelling polymer, characterized in that it has a mean size of less than or equal to 20 μm, in that the said structured oily phase has a melting point of greater than or equal to 40° C. and in that their circularity index is between 0.9 and 1.

    摘要翻译： 本发明涉及包含至少一种疏水性防晒剂并且包含至少一种由至少一种胶凝聚合物构成的油相的校准油性颗粒，其特征在于其具有小于或等于20μm的平均尺寸，因为所述 结构油相具有大于或等于40℃的熔点，并且其圆形度指数在0.9和1之间。

    Oily phase in an aqueous phase dispersion stabilized by cubic gel particles and method of making
    6.
    发明授权
    Oily phase in an aqueous phase dispersion stabilized by cubic gel particles and method of making 失效
    油相中的立体凝胶颗粒稳定的水相分散体和制备方法

    公开(公告)号：US5756108A

    公开(公告)日：1998-05-26

    申请号：US555784

    申请日：1995-11-09

    申请人： Alain Ribier ,  Bruno Biatry

    发明人： Alain Ribier ,  Bruno Biatry

    IPC分类号： A61K47/16 ,  A61K8/02 ,  A61K8/04 ,  A61K8/06 ,  A61K8/34 ,  A61K8/42 ,  A61K8/68 ,  A61K9/127 ,  A61Q19/00 ,  A61Q19/08 ,  B01J13/00 ,  C07C31/22 ,  C07C271/12 ,  A61K7/00 ,  A01N25/04

    CPC分类号： A61K8/042 ,  A61K8/06 ,  A61K8/062 ,  A61K8/345 ,  A61K8/42 ,  A61K8/68 ,  A61K9/1274 ,  A61Q19/00 ,  A61Q19/08 ,  Y10S514/846 ,  Y10S514/847 ,  Y10S514/939 ,  Y10S516/90

    摘要： Composition in the form of a stable dispersion. This composition comprises:(a) from 60 to 98% by weight of an aqueous phase, and (b) from 2 to 40% by weight of an oily phase, said oily phase being dispersed in said aqueous phase and stabilized using cubic gel particles, said particles being essentially formed of: (i) 0.1 to 15% by weight, relative to the total weight of the composition, of at least one component selected from the group consisting of 3,7,11,15-tetramethyl-1,2,3-hexadecanetriol or phytanetriol, N-2-alkoxycarbonyl derivatives of N-methylglucamine and unsaturated fatty acid monoglycerides, and (ii) 0.05 to 3% by weight, relative to the total weight of the composition, of a dispersing and stabilizing agent, said agent being selected from the group consisting of surface-active agents which are water-soluble at room temperature, containing a linear or branched, saturated or unsaturated fatty chain having from 8 to 22 carbon atoms. Use in particular in the cosmetic, dermatological and pharmaceutical fields.

    摘要翻译： 组合形式的稳定分散体。 该组合物包含：（a）60至98重量％的水相，和（b）2至40重量％的油相，所述油相分散在所述水相中，并使用立方体凝胶颗粒 所述颗粒基本上由以下组成：（i）相对于所述组合物的总重量为0.1至15重量％的至少一种选自下组的组分：3,7,11,15-四甲基-1， 2,3-十六烷三醇或植烷三醇，N-甲基葡糖胺和不饱和脂肪酸单甘油酯的N-2-烷氧基羰基衍生物，和（ii）相对于组合物总重量为0.05-3重量％的分散和稳定剂 所述试剂选自在室温下为水溶性的含有8-22个碳原子的直链或支链，饱和或不饱和脂肪链的表面活性剂。 特别用于化妆品，皮肤病学和制药领域。