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公开(公告)号:US11999689B2
公开(公告)日:2024-06-04
申请号:US17551333
申请日:2021-12-15
发明人: Chen Yang , Shuhua Zhang , Yufeng Yang , Xiucai Liu
CPC分类号: C07C51/43 , C07C55/02 , C07B2200/13
摘要: The present disclosure provides a method for extracting long chain dicarboxylic acid, the method comprising: (1) subjecting a long chain dicarboxylic acid fermentation broth to a primary membrane filtration treatment to give a first filtrate; subjecting the first filtrate to decolorization, crystallization, and solid-liquid separation to give a first solid; (2) redissolving the first solid in water to form a solution; subjecting the solution to decolorization, crystallization by acidification, and solid-liquid separation to give a second solid. By the method, the resulted long chain dicarboxylic acid product has a high purity and no residual organic solvent.
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2.
公开(公告)号:US20240150523A1
公开(公告)日:2024-05-09
申请号:US18412986
申请日:2024-01-15
发明人: Wutong FENG , Yuanbo ZHAO , Xiucai LIU
CPC分类号: C08G69/265 , C08G69/28
摘要: The present disclosure provides a semi-aromatic copolyamide, its preparation method, compositions, and a molded product thereof. The semi-aromatic copolyamide is formed from raw materials including diacid monomers and diamine monomers. The diacid monomers include aromatic diacid or derivatives of the aromatic diacid and aliphatic diacid. The diamine monomers include decamethylene diamine and pentamethylene diamine. The molar ratio of the decamethylene diamine to the pentamethylene diamine is in a range of 1:1 to 30:1.
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公开(公告)号:US20230383095A1
公开(公告)日:2023-11-30
申请号:US18448642
申请日:2023-08-11
申请人: Cathay Biotech Inc. , CIBT America Inc. , Shanxi Synthetic Biology Institute Co., Ltd. , Cathay (Taiyuan) Biomaterial Co., Ltd.
发明人: Yuanping Li , Bing Guan , Xiucai Liu
CPC分类号: C08K7/14 , C08K3/32 , C08K2003/329
摘要: Provided are a flame-retardant polyamide glass fiber composition and a preparation method therefor. The flame-retardant polyamide glass fiber comprising 40-65 parts by mass of a polyamide resin, 25-40 parts by mass of glass fibers, 0-20 parts by mass of a flame retardant, 0.2-1 part by mass of an antioxidant and 0.1-2 parts by mass of other auxiliaries. The flame-retardant polyamide glass fiber composition provided in the present disclosure not only has a bio-based source, but also has a flame-retardant of V-0 in UL94 and excellent mechanical properties, and can be widely applied to the fields of various engineering plastics with high requirements for flame retardant effect and dimensional stability.
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公开(公告)号:US11806670B2
公开(公告)日:2023-11-07
申请号:US17551335
申请日:2021-12-15
发明人: Chen Yang , Shuhua Zhang , Yufeng Yang , Xiucai Liu
IPC分类号: B01D61/14 , C07C53/126 , C07C55/21 , B01D9/00 , B01D9/02
CPC分类号: B01D61/145 , B01D9/0004 , B01D9/02 , B01D61/147 , B01D2325/02 , C07C53/126 , C07C55/21
摘要: The present disclosure provides a system for extracting long chain dicarboxylic acid, the system comprising:
a primary membrane filtration unit, a first crystallization unit, a first separation unit, a first dissolution tank, a secondary membrane filtration unit, a second separation unit, a second crystallization unit and a third separation unit. By the system for extracting long chain dicarboxylic acid of an embodiment of the present invention, the resulted long chain dicarboxylic acid product has a high purity, very low and even no residual alkane residue, and organic solvent-free.-
公开(公告)号:US20230203431A1
公开(公告)日:2023-06-29
申请号:US17769459
申请日:2020-01-16
发明人: Jianglin WANG , Wei LI , Qinpei LI , Wenxiao JIANG , Shuya MIN , Xiucai LIU
CPC分类号: C12N1/165 , C12P7/44 , C12R2001/74
摘要: Provided are a Candida tropicalis strain Am2525, with the preservation number thereof being CCTCC NO: M 2019419, and a method for producing long-chain dicarboxylic acids by means of fermenting the strain. The method for producing the long-chain dicarboxylic acids comprises preparing a seed solution by means of the Candida tropicalis strain Am2525 and producing the long-chain dicarboxylic acids via fermentation of the seed solution. Compared with the parent, the Candida tropicalis strain Am2525 has an enhanced resistance to the toxicity of a substrate decane, improves the productivity of long-chain dicarboxylic acids, reduces the cost of production, subsequent separation and purification are simple, and the fermentation production process is easy to implement on a large scale.
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公开(公告)号:US11485986B2
公开(公告)日:2022-11-01
申请号:US16961106
申请日:2018-01-09
发明人: Howard Chou , Ling Chen , Yunfeng Lei , Xiucai Liu
摘要: The invention provides microorganisms genetically modified to overexpress biofilm dispersal related polypeptides to enhance the production of lysine and lysine derivatives by the microorganism, method of generating such microorganism, and methods of producing lysine and lysine derivatives using the genetically modified microorganisms.
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公开(公告)号:US11319561B2
公开(公告)日:2022-05-03
申请号:US16207721
申请日:2018-12-03
发明人: Min Xu , Chen Yang , Bingbing Qin , Naiqiang Li , Xiucai Liu
IPC分类号: C12P7/64 , C07C55/02 , C12P7/6409 , C12P7/44
摘要: The present invention discloses a method for producing a long chain dicarboxylic acid by fermentation as well as a fermentation broth, a treated fermentation broth and a wastewater. The salt content in the fermentation broth is controlled to be below 20% by the fermentation method of the present invention. The method for producing a long chain dicarboxylic acid by fermentation provided by the present invention can effectively reduce the amount of alkali used in the fermentation process and the amount of acid used in the subsequent extraction of the long chain dicarboxylic acid, thereby reducing the amount of salt in the whole production process of the long chain dicarboxylic acid. At the same time, the method of the present invention also has many advantages such as shortening the fermentation time, increasing the acid production, reducing the amount of medium, and suitable for the production of various types of long-chain dicarboxylic acids, etc. Compared with the existing production process, the method of the present invention not only has significant cost advantages, but also can effectively reduce the pressure on resource and environment, thus it has a very obvious value advantage in industrialization.
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公开(公告)号:US20220106249A1
公开(公告)日:2022-04-07
申请号:US17551333
申请日:2021-12-15
发明人: Chen Yang , Shuhua Zhang , Yufeng Yang , Xiucai Liu
摘要: The present disclosure provides a method for extracting long chain dicarboxylic acid, the method comprising: (1) subjecting a long chain dicarboxylic acid fermentation broth to a primary membrane filtration treatment to give a first filtrate; subjecting the first filtrate to decolorization, crystallization, and solid-liquid separation to give a first solid; (2) redissolving the first solid in water to form a solution; subjecting the solution to decolorization, crystallization by acidification, and solid-liquid separation to give a second solid. By the method, the resulted long chain dicarboxylic acid product has a high purity and no residual organic solvent.
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公开(公告)号:US11229881B2
公开(公告)日:2022-01-25
申请号:US16887153
申请日:2020-05-29
发明人: Chen Yang , Shuhua Zhang , Yufeng Yang , Xiucai Liu
摘要: The present disclosure provides a method and a system for extracting long chain dicarboxylic acid, the method comprising: (1) subjecting a long chain dicarboxylic acid fermentation broth to a primary membrane filtration treatment to give a first filtrate; subjecting the first filtrate to decolorization, acidification/crystallization, and solid-liquid separation treatments to give a first solid; (2) mixing the first solid, a base and water to form a solution; subjecting the solution to a secondary membrane filtration treatment to give a second filtrate; subjecting the second filtrate to decolorization, acidification/crystallization, and solid-liquid separation treatments to give a second solid; and (3) mixing the second solid and water to form a mixture; subjecting the mixture to a thermostatic treatment at 105-150° C., followed by cooling for crystallization and solid-liquid separation treatment. By the method, the resulted long chain dicarboxylic acid product has a high purity and no residual organic solvent.
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10.
公开(公告)号:US11225677B2
公开(公告)日:2022-01-18
申请号:US16503301
申请日:2019-07-03
发明人: Wenbo Liu , Min Xu , Chen Yang , Howard Chou , Xiucai Liu
摘要: The invention relates to a long-chain dibasic acid with low content of monobasic acid impurity and a production method thereof, in particular to the preparation of a long-chain dibasic acid producing strain by means of directed evolution and homologous recombination, and to the production of a long-chain dibasic acid with low content of monobasic acid impurity by fermentation of said strain. The invention relates to a mutated CYP52A12 gene, homologous gene or variant thereof, which, relative to GenBank Accession Number AY230498 and taking the first base upstream of the start codon ATG as −1, comprises a mutation. The invention relates to a strain comprising said mutated CYP52A12 gene, homologous gene or variant thereof wherein when the strain is fermented to produce a long-chain dibasic acid, the content of monobasic acid impurity in the fermentation product is significantly reduced.
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