公开(公告)号：US20160235535A1

公开(公告)日：2016-08-18

申请号：US15142697

申请日：2016-04-29

申请人： CIBOR, INC.

发明人： Paul Hastings Wooley ,  Haiying Yu

IPC分类号： A61F2/28 ,  A61L27/56 ,  A61L27/32 ,  A61L27/28 ,  A61L27/30 ,  A61L27/42 ,  A61L27/54

CPC分类号： A61F2/28 ,  A61F2002/2835 ,  A61F2002/30011 ,  A61F2002/30062 ,  A61F2002/3092 ,  A61F2310/00161 ,  A61F2310/00173 ,  A61F2310/00796 ,  A61F2310/0097 ,  A61F2310/00976 ,  A61L27/08 ,  A61L27/28 ,  A61L27/306 ,  A61L27/32 ,  A61L27/422 ,  A61L27/54 ,  A61L27/56 ,  A61L2430/02

摘要： A porous, self-sustaining body useful as a scaffold for bone grafting is provided. The scaffold comprises a carbonaceous matrix comprising a continuous phase having a surface and defining a plurality of open spaces throughout the matrix. The internal and external surfaces of the matrix are coated with a layer or film selected from the group consisting of osteogenic materials, therapeutic agents, and combinations thereof. The porous body comprises organic materials and is substantially free of metals. Methods of making and using the porous self-sustaining body are also provided, along with kits for facilitating the same.

摘要翻译： 提供了可用作骨移植用支架的多孔，自维持体。 支架包括碳质基质，其包含具有表面并在整个基质中限定多个开放空间的连续相。 基质的内部和外部表面涂覆有选自成骨材料，治疗剂及其组合的层或膜。 多孔体包含有机材料，基本上不含金属。 还提供了制造和使用多孔自持体的方法以及用于促进其的试剂盒。