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公开(公告)号：US08980948B2
公开(公告)日：2015-03-17
申请号：US13543289
申请日：2012-07-06
IPC分类号： A61K31/5575 , A61K8/69 , A61Q7/00
CPC分类号： A61K8/69 , A61K31/5575 , A61Q7/00
摘要： Travoprost medicament compositions for non-daily topical application are useful for simulating or inducing the growth and/or decreasing the loss and/or increasing the density and/or reducing the heterogeneity in the diameter of human hair shafts/follicles, e.g., for the treatment of androgenic alopecia, such medicament compositions being at least twice applied over a time interval of greater than 24 hours.
摘要翻译： 用于非日常局部应用的曲伏前列素药物组合物可用于模拟或诱导人发丝/毛囊直径的生长和/或减少损失和/或增加密度和/或减少异质性，例如用于治疗 的雄激素性脱发，所述药物组合物在大于24小时的时间间隔内至少施用两次。
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公开(公告)号：US20100190853A1
公开(公告)日：2010-07-29
申请号：US12710382
申请日：2010-02-23
IPC分类号： A61K31/216 , A61P17/14
CPC分类号： A61K8/69 , A61K31/5575 , A61Q7/00
摘要： Travoprost medicament compositions for non-daily topical application are useful for simulating or inducing the growth and/or decreasing the loss and/or increasing the density and/or reducing the heterogeneity in the diameter of human hair shafts/follicles, e.g., for the treatment of androgenic alopecia, such medicament compositions being at least twice applied over a time interval of greater than 24 hours.
摘要翻译： 用于非日常局部应用的曲伏前列素药物组合物可用于模拟或诱导人发丝/毛囊直径的生长和/或减少损失和/或增加密度和/或减少异质性，例如用于治疗 的雄激素性脱发，所述药物组合物在大于24小时的时间间隔内至少施用两次。
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3.发明授权Dermatologic compositions comprising pyrrolidone-5-carboxylic acid and at least one entity chosen from citrulline, arginine and asparagine, and uses thereof in the treatment of atopic dermatitis 有权包含吡咯烷酮-5-羧酸和至少一种选自瓜氨酸，精氨酸和天冬酰胺的实体的皮肤病学组合物及其在治疗特应性皮炎中的用途公开(公告)号：US08795705B2
公开(公告)日：2014-08-05
申请号：US12601113
申请日：2008-05-22
申请人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
发明人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
IPC分类号： A61F2/00
CPC分类号： A61K9/107 , A61K9/06 , A61K31/198 , A61K31/4015 , A61K2300/00
摘要： Combination comprising pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, and use thereof in the treatment of atopic dermatitis The present invention relates to a composition comprising, in a physiologically acceptable carrier, pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, in racemic or isomer form, and salts thereof, for the preparation of a medicament for use in the treatment and/or prevention of atopic dermatitis.
摘要翻译： 包含吡咯烷酮-5-羧酸和至少一种来自瓜氨酸，精氨酸和天冬酰胺的化合物的组合及其在治疗特应性皮炎中的用途本发明涉及一种组合物，其在生理学上可接受的载体中包含吡咯烷酮-5-羧酸 和至少一种来自瓜氨酸，精氨酸和天冬酰胺的化合物，其外消旋或异构体形式及其盐，用于制备用于治疗和/或预防特应性皮炎的药物。
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4.发明申请COMBINATION COMPRISING PYRROLIDONE-5-CARBOXYLIC ACID AND AT LEAST ONE COMPOUND FROM CITRULLINE, ARGININE AND ASPARAGINE, AND USE THEREOF IN THE TREATMENT OF ATOPIC DERMATITIS 有权包含吡咯烷酮-5-羧酸和来自CITRULLINE，ARGININE和ASPARAGINE的至少一种化合物的组合及其在治疗原发性药物中的用途公开(公告)号：US20100291002A1
公开(公告)日：2010-11-18
申请号：US12601113
申请日：2008-05-22
申请人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
发明人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
IPC分类号： A61K31/4015 , A61K9/12 , A61P17/00
CPC分类号： A61K9/107 , A61K9/06 , A61K31/198 , A61K31/4015 , A61K2300/00
摘要： Combination comprising pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, and use thereof in the treatment of atopic dermatitis The present invention relates to a composition comprising, in a physiologically acceptable carrier, pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, in racemic or isomer form, and salts thereof, for the preparation of a medicament for use in the treatment and/or prevention of atopic dermatitis.
摘要翻译： 包含吡咯烷酮-5-羧酸和至少一种来自瓜氨酸，精氨酸和天冬酰胺的化合物的组合及其在治疗特应性皮炎中的用途本发明涉及一种组合物，其在生理学上可接受的载体中包含吡咯烷酮-5-羧酸 和至少一种来自瓜氨酸，精氨酸和天冬酰胺的化合物，其外消旋或异构体形式及其盐，用于制备用于治疗和/或预防特应性皮炎的药物。
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公开(公告)号：US08420632B2
公开(公告)日：2013-04-16
申请号：US13381234
申请日：2010-06-28
申请人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlène Schuppli
发明人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlène Schuppli
IPC分类号： A61K31/551 , A61K31/4965 , A61K31/497 , C07D295/26 , C07D471/04 , C07D413/12 , C07D401/12 , C07D403/12
CPC分类号： C07D215/14 , A61K31/4965 , A61K31/497 , A61K31/551 , C07D209/10 , C07D209/12 , C07D209/20 , C07D209/24 , C07D209/26 , C07D213/30 , C07D213/55 , C07D213/56 , C07D213/68 , C07D261/20 , C07D295/15 , C07D295/26 , C07D471/04 , Y02A50/411
摘要： Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
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公开(公告)号：US08227514B2
公开(公告)日：2012-07-24
申请号：US12710382
申请日：2010-02-23
IPC分类号： A61K31/5575
CPC分类号： A61K8/69 , A61K31/5575 , A61Q7/00
摘要： Travoprost medicament compositions for non-daily topical application are useful for simulating or inducing the growth and/or decreasing the loss and/or increasing the density and/or reducing the heterogeneity in the diameter of human hair shafts/follicles, e.g., for the treatment of androgenic alopecia, such medicament compositions being at least twice applied over a time interval of greater than 24 hours.
摘要翻译： 用于非日常局部应用的曲伏前列素药物组合物可用于模拟或诱导人发丝/毛囊直径的生长和/或减少损失和/或增加密度和/或减少异质性，例如用于治疗 的雄激素性脱发，所述药物组合物在大于24小时的时间间隔内至少施用两次。
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7.发明申请NOVEL BENZENESULFONAMIDE COMPOUNDS, METHOD FOR SYNTHESIZING SAME, AND USE THEREOF IN MEDICINE AS WELL AS IN COSMETICS 有权新型苯并噻二唑化合物，其合成方法及其在医药中的用途如同化妆品公开(公告)号：US20120323006A1
公开(公告)日：2012-12-20
申请号：US13381234
申请日：2010-06-28
申请人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlene Schuppli
发明人： Laurence Clary , Sandrine Chambon , Laurent Chantalat , Carine Rosignoli , Olivier Roye , Jean-Claude Pascal , Marlene Schuppli
IPC分类号： C07D295/26 , C07D471/04 , C07D413/12 , C07D401/12 , C07D403/12
CPC分类号： C07D215/14 , A61K31/4965 , A61K31/497 , A61K31/551 , C07D209/10 , C07D209/12 , C07D209/20 , C07D209/24 , C07D209/26 , C07D213/30 , C07D213/55 , C07D213/56 , C07D213/68 , C07D261/20 , C07D295/15 , C07D295/26 , C07D471/04 , Y02A50/411
摘要： Benzenesulfonamide compounds having a structure of formula (I) are described. Also described, are methods for synthesizing the compounds and to the use thereof in pharmaceutical compositions for human or veterinary medicine and in cosmetic compositions.
摘要翻译： 描述具有式（I）结构的苯磺酰胺化合物。 还描述了用于合成化合物的方法及其在人或兽医学药物组合物和化妆品组合物中的用途。
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公开(公告)号：US20120270941A1
公开(公告)日：2012-10-25
申请号：US13543289
申请日：2012-07-06
IPC分类号： A61K31/215 , A61P17/14
CPC分类号： A61K8/69 , A61K31/5575 , A61Q7/00
摘要： Travoprost medicament compositions for non-daily topical application are useful for simulating or inducing the growth and/or decreasing the loss and/or increasing the density and/or reducing the heterogeneity in the diameter of human hair shafts/follicles, e.g., for the treatment of androgenic alopecia, such medicament compositions being at least twice applied over a time interval of greater than 24 hours.
摘要翻译： 用于非日常局部应用的曲伏前列素药物组合物可用于模拟或诱导人发丝/毛囊直径的生长和/或减少损失和/或增加密度和/或减少异质性，例如用于治疗 的雄激素性脱发，所述药物组合物在大于24小时的时间间隔内至少施用两次。
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9.发明申请COMBINATION COMPRISING PYRROLIDONE-5-CARBOXYLIC ACID AND AT LEAST ONE COMPOUND FROM CITRULLINE, ARGININE AND ASPRAGINE, AND USE THEREOF IN THE TRATMENT OF ATOPIC DERMATITIS 审中-公开包含吡咯烷酮-5-羧酸和来自CITRULLINE，ARGININE和ASPRAGINE的至少一种化合物的组合及其在治疗原发性药物中的用途公开(公告)号：US20100324111A1
公开(公告)日：2010-12-23
申请号：US12790194
申请日：2010-05-28
申请人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
发明人： Johannes Voegel , Emmanuelle At , Carine Rosignoli
IPC分类号： A61K31/4015 , A61P29/00
CPC分类号： A61K31/4015 , A61K9/0014 , A61K31/198 , A61K47/12 , A61K47/183 , A61K2300/00
摘要： The present invention relates to a composition comprising, in a physiologically acceptable carrier, pyrrolidone-5-carboxylic acid and at least one compound from citrulline, arginine and asparagine, in racemic or isomer form, and salts thereof, for the preparation of a medicament for use in the treatment and/or prevention of atopic dermatitis.
摘要翻译： 本发明涉及一种组合物，其在生理上可接受的载体中包含吡咯烷酮-5-羧酸和至少一种来自瓜氨酸，精氨酸和天冬酰胺的化合物，其外消旋或异构体形式及其盐，用于制备用于 用于治疗和/或预防特应性皮炎。
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