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公开(公告)号：US08981317B2
公开(公告)日：2015-03-17
申请号：US13320610
申请日：2010-05-12
申请人： Juergen Schreiber , Joerg Opitz , Carola Gerich , Jens Fehre , Georg Salomon , Ralf Nanke
发明人： Juergen Schreiber , Joerg Opitz , Carola Gerich , Jens Fehre , Georg Salomon , Ralf Nanke
CPC分类号： G01N21/6486 , A61B5/0059 , G01N21/6408
摘要： The invention relates to a method and to an apparatus for recognizing tumorous living cell tissue. It furthermore relates to a method and to an apparatus for recognizing tumorous cell tissue at collected living cell tissue samples. In the method, electromagnetic radiation is emitted with local definition onto cell tissue by a radiation source and, after deactivation of the radiation source, the decay behavior of the inherent fluorescence intensity of the cell tissue excited by the electromagnetic radiation is detected at the cell tissue in a time resolved and spectrally resolved manner at known sampling rate(s) for at least one wavelength using a detector. The difference autocorrelation function C(t) of the intensity decay behavior is determined using the determined measured intensity values, the fractal dimension DF for the respective irradiated cell tissue is calculated from this and the value of the fractal dimension DF is used for a classification with respect to a presence of a tumor in the respective irradiated cell tissue.
摘要翻译： 本发明涉及用于识别肿瘤活细胞组织的方法和装置。 此外，本发明还涉及用于在收集的活细胞组织样品处识别肿瘤细胞组织的方法和装置。 在该方法中，电磁辐射通过辐射源以局部定义发射到细胞组织上，并且在放射源失活之后，在细胞组织处检测由电磁辐射激发的细胞组织的固有荧光强度的衰变行为 以使用检测器的至少一个波长的已知采样速率以时间分辨和频谱分辨的方式。 使用确定的测量强度值确定强度衰减行为的差分自相关函数C（t），并从其计算相应的照射细胞组织的分形维数DF，并且使用分形维数DF的值进行分类， 相对于各自照射的细胞组织中肿瘤的存在。
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公开(公告)号：US08364247B2
公开(公告)日：2013-01-29
申请号：US12960678
申请日：2010-12-06
IPC分类号： A61B6/00
CPC分类号： G01N21/6486 , A01K45/007 , G01N21/6408 , G01N33/08 , G01N2021/6484 , G01N2201/0697 , G01N2201/1293
摘要： The invention relates to methods for determining the sex of birds' eggs. It can be used for an early determination of the sex, in particular in poultry farming, and in this respect also with non-incubated eggs. In the method in accordance with the invention, electromagnetic radiation is emitted onto the blastodisk of an egg by a radiation source and, after a switching off of the radiation source, the decay behavior of the autofluorescence intensity excited by the electromagnetic radiation is detected by a detector at the irradiated region of the blastodisk with time resolution and spectral resolution for at least one wavelength of the autofluorescence. The fractal dimension DF is calculated using the determined measured intensity values and the value of the fractal dimension DF is compared with a species-specific and sex-specific limit value, wherein, when the limit value is exceeded, the respective egg is classified as female and, when it is not reached, the egg is classified as male.
摘要翻译： 本发明涉及确定鸡蛋性别的方法。 它可以用于早期确定性别，特别是在家禽养殖中，在这方面也可以用未孵化的鸡蛋。 在根据本发明的方法中，电磁辐射通过辐射源发射到蛋的胚盘上，并且在辐射源的切断之后，由电磁辐射激发的自发荧光强度的衰减行为由 在自发荧光的至少一个波长的时间分辨率和光谱分辨率下的辐射区域的探测器。 使用确定的测量强度值计算分形维数DF，并将分形维数DF的值与物种特异性和性别特异性极限值进行比较，其中当超过极限值时，将各卵分类为女性 而当没有达到时，将鸡蛋分类为男性。
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公开(公告)号：US20120252057A1
公开(公告)日：2012-10-04
申请号：US13320610
申请日：2010-05-12
申请人： Juergen Schrelber , Joerg Opitz , Carola Gerich , Jens Fehre , Georg Salomon , Ralf Nanke
发明人： Juergen Schrelber , Joerg Opitz , Carola Gerich , Jens Fehre , Georg Salomon , Ralf Nanke
CPC分类号： G01N21/6486 , A61B5/0059 , G01N21/6408
摘要： The invention relates to a method and to an apparatus for recognizing tumorous living cell tissue. It furthermore relates to a method and to an apparatus for recognizing tumorous cell tissue at collected living cell tissue samples. In the method, electromagnetic radiation is emitted with local definition onto cell tissue by a radiation source and, after deactivation of the radiation source, the decay behavior of the inherent fluorescence intensity of the cell tissue excited by the electromagnetic radiation is detected at the cell tissue in a time resolved and spectrally resolved manner at known sampling rate(s) for at least one wavelength using a detector. The difference autocorrelation function C(t) of the intensity decay behavior is determined using the determined measured intensity values, the fractal dimension DF for the respective irradiated cell tissue is calculated from this and the value of the fractal dimension DF is used for a classification with respect to a presence of a tumor in the respective irradiated cell tissue.
摘要翻译： 本发明涉及用于识别肿瘤活细胞组织的方法和装置。 此外，本发明还涉及用于在收集的活细胞组织样品处识别肿瘤细胞组织的方法和装置。 在该方法中，电磁辐射通过辐射源以局部定义发射到细胞组织上，并且在放射源失活之后，在细胞组织处检测由电磁辐射激发的细胞组织的固有荧光强度的衰变行为 以使用检测器的至少一个波长的已知采样速率以时间分辨和频谱分辨的方式。 使用确定的测量强度值确定强度衰减行为的差分自相关函数C（t），并从其计算相应的照射细胞组织的分形维数DF，并且使用分形维数DF的值进行分类， 相对于各自照射的细胞组织中肿瘤的存在。
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公开(公告)号：US20110144473A1
公开(公告)日：2011-06-16
申请号：US12960678
申请日：2010-12-06
IPC分类号： A61B5/05
CPC分类号： G01N21/6486 , A01K45/007 , G01N21/6408 , G01N33/08 , G01N2021/6484 , G01N2201/0697 , G01N2201/1293
摘要： The invention relates to methods for determining the sex of birds' eggs. It can be used for an early determination of the sex, in particular in poultry farming, and in this respect also with non-incubated eggs. In the method in accordance with the invention, electromagnetic radiation is emitted onto the blastodisk of an egg by a radiation source and, after a switching off of the radiation source, the decay behavior of the autofluorescence intensity excited by the electromagnetic radiation is detected by a detector at the irradiated region of the blastodisk with time resolution and spectral resolution for at least one wavelength of the autofluorescence. The fractal dimension DF is calculated using the determined measured intensity values and the value of the fractal dimension DF is compared with a species-specific and sex-specific limit value, wherein, when the limit value is exceeded, the respective egg is classified as female and, when it is not reached, the egg is classified as male.
摘要翻译： 本发明涉及确定鸡蛋性别的方法。 它可以用于早期确定性别，特别是在家禽养殖中，在这方面也可以用未孵化的鸡蛋。 在根据本发明的方法中，电磁辐射通过辐射源发射到蛋的胚盘上，并且在辐射源的切断之后，由电磁辐射激发的自发荧光强度的衰减行为由 在自发荧光的至少一个波长的时间分辨率和光谱分辨率下的辐射区域的探测器。 使用确定的测量强度值计算分形维数DF，并将分形维数DF的值与物种特异性和性别特异性极限值进行比较，其中当超过极限值时，将各卵分类为女性 而当没有达到时，将鸡蛋分类为男性。
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