APPARATUS FOR MOUNTING SEAT BELT RETRACTOR FOR VEHICLE
    1.
    发明申请
    APPARATUS FOR MOUNTING SEAT BELT RETRACTOR FOR VEHICLE 审中-公开
    装置用于车辆的座椅带扣装置

    公开(公告)号:US20130146697A1

    公开(公告)日:2013-06-13

    申请号:US13605558

    申请日:2012-09-06

    IPC分类号: B60R22/34

    摘要: An apparatus for mounting a seat belt retractor for a vehicle is capable of promoting the ease with which a seat belt retractor is mounted on a center pillar by a worker, and minimizing an amount of movement of the seat belt refractor towards the interior of a vehicle body in the event of a broadside collision.

    摘要翻译: 一种用于安装用于车辆的安全带卷收器的装置能够促进安全带卷收器由工作人员安装在中心支柱上的容易性,并且使安全带折射器朝向车辆内部的移动量最小化 身体在发生侧面碰撞时。

    NOVEL G PROTEIN COUPLED RECEPTOR PROTEIN AND USE THEREOF
    2.
    发明申请
    NOVEL G PROTEIN COUPLED RECEPTOR PROTEIN AND USE THEREOF 有权
    新型G蛋白偶联受体蛋白及其用途

    公开(公告)号:US20120141488A1

    公开(公告)日:2012-06-07

    申请号:US13322304

    申请日:2009-09-07

    CPC分类号: C07K14/705 G01N33/5041

    摘要: Disclosed are novel GPCR (G Protein Coupled Receptor) proteins and genes encoding the same. Also provided is the use of the proteins and the genes. Particularly, contemplated are a novel GPCR (G Protein Coupled Receptor) polypeptide, a polynucleotide coding for the same, a recombinant vector carrying the polynucleotide or a fragment thereof, host cells transformed with the vector, a transgenic animal infected with the vector. Also, a composition for detecting a cancer marker, comprising an agent capable of measuring the expression level of mRNA or protein of the GPCR polynucleotide, a kit for the diagnosis of cancer, comprising the composition, and a method for detecting the GPCR polypeptide and a gene encoding the polypeptide are provided. Further, a composition for the treatment and prevention of cancer, comprising an oligonucleotide inhibiting the expression of a gene encoding the GPCR polypeptide or an antibody against the GPCR protein, and a method for screening a modulator of the GPCR protein or a cancer therapeutic agent are provided.

    摘要翻译: 公开了新型GPCR(G蛋白偶联受体)蛋白和编码其的基因。 还提供了蛋白质和基因的使用。 特别地,考虑了新型GPCR(G蛋白偶联受体)多肽,编码它的多核苷酸,携带多核苷酸或其片段的重组载体,用该载体转化的宿主细胞,用载体感染的转基因动物。 另外,含有能够测定GPCR多核苷酸的mRNA或蛋白质的表达量的试剂,癌症诊断用试剂盒,含有该组合物的检测癌标记物的组合物,以及检测GPCR多肽的方法和 提供编码多肽的基因。 此外,用于治疗和预防癌症的组合物包含抑制GPCR多肽或编码GPCR蛋白的抗体表达的寡核苷酸以及筛选GPCR蛋白或癌症治疗剂的调节剂的方法, 提供。

    G protein coupled receptor protein and use thereof
    3.
    发明授权
    G protein coupled receptor protein and use thereof 有权
    G蛋白偶联受体蛋白及其用途

    公开(公告)号:US09034327B2

    公开(公告)日:2015-05-19

    申请号:US13322304

    申请日:2009-09-07

    CPC分类号: C07K14/705 G01N33/5041

    摘要: Disclosed are novel GPCR (G Protein Coupled Receptor) proteins and genes encoding the same. Also provided is the use of the proteins and the genes. Particularly, contemplated are a novel GPCR (G Protein Coupled Receptor) polypeptide, a polynucleotide coding for the same, a recombinant vector carrying the polynucleotide or a fragment thereof, host cells transformed with the vector, a transgenic animal infected with the vector. Also, a composition for detecting a cancer marker, comprising an agent capable of measuring the expression level of mRNA or protein of the GPCR polynucleotide, a kit for the diagnosis of cancer, comprising the composition, and a method for detecting the GPCR polypeptide and a gene encoding the polypeptide are provided. Further, a composition for the treatment and prevention of cancer, comprising an oligonucleotide inhibiting the expression of a gene encoding the GPCR polypeptide or an antibody against the GPCR protein, and a method for screening a modulator of the GPCR protein or a cancer therapeutic agent are provided.

    摘要翻译: 公开了新型GPCR(G蛋白偶联受体)蛋白和编码其的基因。 还提供了蛋白质和基因的使用。 特别地,考虑了新型GPCR(G蛋白偶联受体)多肽,编码它的多核苷酸,携带多核苷酸或其片段的重组载体,用该载体转化的宿主细胞,用载体感染的转基因动物。 另外,含有能够测定GPCR多核苷酸的mRNA或蛋白质的表达量的试剂,癌症诊断用试剂盒,含有该组合物的检测癌标记物的组合物,以及检测GPCR多肽的方法和 提供编码多肽的基因。 此外,用于治疗和预防癌症的组合物包含抑制GPCR多肽或编码GPCR蛋白的抗体表达的寡核苷酸以及筛选GPCR蛋白或癌症治疗剂的调节剂的方法, 提供。