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公开(公告)号：US08425529B2
公开(公告)日：2013-04-23
申请号：US12894824
申请日：2010-09-30
申请人： Bryan D. Milz , Christine Herrmann
发明人： Bryan D. Milz , Christine Herrmann
IPC分类号： A61B17/58
CPC分类号： A61F2/4611 , A61F2/4465 , A61F2002/2817 , A61F2002/2835 , A61F2002/3008 , A61F2002/30266 , A61F2002/30304 , A61F2002/30538 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/3082 , A61F2002/30843 , A61F2002/30879 , A61F2002/30883 , A61F2002/4475 , A61F2002/4627
摘要： A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.
摘要翻译： 公开了假体椎间间隔物。 间隔件优选地包括主体和远离主体延伸的界面，以便在间隔件植入期间使用。 还公开了在这种过程期间使用的间隔物和工具的植入方法。
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公开(公告)号：US20050003559A1
公开(公告)日：2005-01-06
申请号：US10658240
申请日：2003-09-09
申请人： Ekkehardt Weber , Dagmar Guenther , Sebastian Zellmer , Martina Goldberg , Christian Bergmann , Christine Herrmann , Anita Huske , Anja Mueller
发明人： Ekkehardt Weber , Dagmar Guenther , Sebastian Zellmer , Martina Goldberg , Christian Bergmann , Christine Herrmann , Anita Huske , Anja Mueller
IPC分类号： G01N33/50 , G01N33/543 , G01N33/553 , G01N33/574
CPC分类号： G01N33/574 , G01N33/5091 , G01N33/54326
摘要： The present invention provides an advanced immunomagnetic method for the isolation of specific target cells from cell populations and suspensions of cell populations, espeacially tumor cells from peripheral blood bone, marrow aspirates, ascities and other body fluids. The invention also relates to a kit for performing the method for the isolation of specific target cells from body fluids.
摘要翻译： 本发明提供了用于从细胞群体分离特异性靶细胞和细胞群体的悬浮液，特别是来自外周血骨骼的肿瘤细胞，骨髓抽吸物，上皮和其他体液的高级免疫磁性方法。 本发明还涉及用于从体液中分离特异性靶细胞的方法的试剂盒。
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公开(公告)号：US09320610B2
公开(公告)日：2016-04-26
申请号：US13587205
申请日：2012-08-16
CPC分类号： A61F2/447 , A61F2/442 , A61F2/4611 , A61F2002/30281 , A61F2002/3039 , A61F2002/30397 , A61F2002/304 , A61F2002/30418 , A61F2002/30434 , A61F2002/30507 , A61F2002/30523 , A61F2002/30551 , A61F2002/30556 , A61F2002/30579 , A61F2002/30598 , A61F2002/30601 , A61F2002/30607 , A61F2002/30622 , A61F2002/30777 , A61F2002/30785 , A61F2002/30827 , A61F2002/30843 , A61F2002/30878 , A61F2002/30892 , A61F2002/30904 , A61F2002/4623 , A61F2002/4624 , A61F2002/4627 , A61F2002/4628
摘要： An expandable implant (210, 410) includes top and bottom plates (220, 250, 420, 450) having angled inner surfaces (222, 252, 422, 452) that interact with expansion members (300, 302, 500, 502). The expansion members (300, 302, 500, 502) may be situated on an actuator (280, 480), and may include at least one vertical projection (312, 314, 512, 514) for interacting with a recess (230, 430) in the plates (220, 250, 420, 450). In some instances, rotation of the actuator (280, 480) in opposing directions about a longitudinal axis may cause the expansion members (300, 302, 500, 502) to move toward or away from one another, thereby resulting in separation or collapse of the top and bottom plates (220, 250, 420, 450). Pins (316, 516) may also be associated with the expansion members (300, 302, 500, 502) and received in respective slots (318, 518) in the plates (220, 250, 420, 450).
摘要翻译： 可扩展植入物（210,410）包括具有与膨胀构件（300,302,500,502）相互作用的具有成角度的内表面（222,252,422,452）的顶板和底板（220,250,420,450）。 膨胀构件（300,302,500,502）可以位于致动器（280,480）上，并且可以包括至少一个垂直突起（312,314,512,514），用于与凹部（230,430）相互作用 ）在板（220,250,420,450）中。 在一些情况下，致动器（280,480）围绕纵向轴线在相反方向上的旋转可能导致膨胀构件（300,302,500,450）朝向或远离彼此移动，从而导致分离或塌陷 顶板和底板（220,250,420,450）。 引脚（316,516）也可以与扩展构件（300,302,500，502,502）相关联并且被接收在板（220,250,420,450）中相应的槽（318,518）中。
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公开(公告)号：US20130211526A1
公开(公告)日：2013-08-15
申请号：US13587205
申请日：2012-08-16
IPC分类号： A61F2/44
CPC分类号： A61F2/447 , A61F2/442 , A61F2/4611 , A61F2002/30281 , A61F2002/3039 , A61F2002/30397 , A61F2002/304 , A61F2002/30418 , A61F2002/30434 , A61F2002/30507 , A61F2002/30523 , A61F2002/30551 , A61F2002/30556 , A61F2002/30579 , A61F2002/30598 , A61F2002/30601 , A61F2002/30607 , A61F2002/30622 , A61F2002/30777 , A61F2002/30785 , A61F2002/30827 , A61F2002/30843 , A61F2002/30878 , A61F2002/30892 , A61F2002/30904 , A61F2002/4623 , A61F2002/4624 , A61F2002/4627 , A61F2002/4628
摘要： An expandable implant (210, 410) includes top and bottom plates (220, 250, 420, 450) having angled inner surfaces (222, 252, 422, 452) that interact with expansion members (300, 302, 500, 502). The expansion members (300, 302, 500, 502) may be situated on an actuator (280, 480), and may include at least one vertical projection (312, 314, 512, 514) for interacting with a recess (230, 430) in the plates (220, 250, 420, 450). In some instances, rotation of the actuator (280, 480) in opposing directions about a longitudinal axis may cause the expansion members (300, 302, 500, 502) to move toward or away from one another, thereby resulting in separation or collapse of the top and bottom plates (220, 250, 420, 450). Pins (316, 516) may also be associated with the expansion members (300, 302, 500, 502) and received in respective slots (318, 518) in the plates (220, 250, 420, 450).
摘要翻译： 可扩展植入物（210,410）包括具有与膨胀构件（300,302,500,502）相互作用的具有成角度的内表面（222,252,422,452）的顶板和底板（220,250,420,450）。 膨胀构件（300,302,500,502）可以位于致动器（280,480）上，并且可以包括至少一个垂直突起（312,314,512,514），用于与凹部（230,430）相互作用 ）在板（220,250,420,450）中。 在一些情况下，致动器（280,480）围绕纵向轴线在相反方向上的旋转可能导致膨胀构件（300,302,500,450）朝向或远离彼此移动，从而导致分离或塌陷 顶板和底板（220,250,420,450）。 引脚（316,516）也可以与扩展构件（300,302,500，502,502）相关联并且被接收在板（220,250,420,450）中相应的槽（318,518）中。
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公开(公告)号：US08858637B2
公开(公告)日：2014-10-14
申请号：US12894796
申请日：2010-09-30
CPC分类号： A61F2/442 , A61F2/4455 , A61F2/4465 , A61F2/4611 , A61F2002/2817 , A61F2002/2835 , A61F2002/3008 , A61F2002/30266 , A61F2002/30304 , A61F2002/30538 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/3082 , A61F2002/30843 , A61F2002/30879 , A61F2002/30883 , A61F2002/4475 , A61F2002/4627
摘要： A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. The interface can be a rail including a neck portion connected to the body and a lip portion connected to the neck portion. The lip portion can be wider than the neck portion in a direction extending between the top and bottom surfaces of the implant. Methods of implanting the spacer and tools used during such procedure are also disclosed.
摘要翻译： 公开了假体椎间间隔物。 间隔件优选地包括主体和远离主体延伸的界面，以便在间隔件植入期间使用。 接口可以是包括连接到主体的颈部部分和连接到颈部的唇部的轨道。 唇部可以在植入物的顶表面和底表面之间延伸的方向上比颈部宽。 还公开了在这种过程期间使用的间隔物和工具的植入方法。
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公开(公告)号：US20120083884A1
公开(公告)日：2012-04-05
申请号：US12894796
申请日：2010-09-30
IPC分类号： A61F2/44
CPC分类号： A61F2/442 , A61F2/4455 , A61F2/4465 , A61F2/4611 , A61F2002/2817 , A61F2002/2835 , A61F2002/3008 , A61F2002/30266 , A61F2002/30304 , A61F2002/30538 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/3082 , A61F2002/30843 , A61F2002/30879 , A61F2002/30883 , A61F2002/4475 , A61F2002/4627
摘要： A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.
摘要翻译： 公开了假体椎间间隔物。 间隔件优选地包括主体和远离主体延伸的界面，以便在间隔件植入期间使用。 还公开了在这种过程期间使用的间隔物和工具的植入方法。
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公开(公告)号：US20120083852A1
公开(公告)日：2012-04-05
申请号：US12894824
申请日：2010-09-30
申请人： Bryan D. Milz , Christine Herrmann
发明人： Bryan D. Milz , Christine Herrmann
IPC分类号： A61B17/56
CPC分类号： A61F2/4611 , A61F2/4465 , A61F2002/2817 , A61F2002/2835 , A61F2002/3008 , A61F2002/30266 , A61F2002/30304 , A61F2002/30538 , A61F2002/30777 , A61F2002/30779 , A61F2002/30785 , A61F2002/3082 , A61F2002/30843 , A61F2002/30879 , A61F2002/30883 , A61F2002/4475 , A61F2002/4627
摘要： A prosthetic intervertebral spacer is disclosed. The spacer preferably includes a body and an interface extending away from the body for use during implantation of the spacer. Methods of implanting the spacer and tools used during such procedure are also disclosed.
摘要翻译： 公开了假体椎间间隔物。 间隔件优选地包括主体和远离主体延伸的界面，以便在间隔件植入期间使用。 还公开了在这种过程期间使用的间隔物和工具的植入方法。
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