公开(公告)号：US09110081B2

公开(公告)日：2015-08-18

申请号：US13148252

申请日：2010-02-11

Applicant: Mark Pimentel ,  Christopher Chang

Inventor： Mark Pimentel ,  Christopher Chang

IPC: G01N33/53 ,  G01N33/68

CPC classification number: G01N33/573 ,  G01N33/6893 ,  G01N2333/24 ,  G01N2333/25 ,  G01N2333/922 ,  G01N2800/065 ,  G01N2800/52

Abstract: Methods for preventing IBS, reducing the likelihood of developing IBS and/or treating IBS by administering COT inhibitors and/or COT neutralizers to a subject in need thereof are described. Methods of eliciting a specific immune response and methods of vaccinating a subject to prevent IBS or to reduce the likelihood of developing or having IBS are also provided. Methods of diagnosing IBS by detecting the presence or absence of COT or a COT marker in a subject are described.

Abstract translation: 描述了通过向有需要的受试者施用COT抑制剂和/或COT中和剂来预防IBS，降低发展IBS和/或治疗IBS的可能性的方法。 还提供了引发特异性免疫应答的方法和接种受试者以防止IBS或降低发展或具有IBS的可能性的方法。 描述了通过检测受试者中COT或COT标记物的存在或不存在来诊断IBS的方法。

公开(公告)号：US08231660B2

公开(公告)日：2012-07-31

申请号：US12543656

申请日：2009-08-19

Applicant: Kingsley R. Chin ,  Christopher Chang ,  Ernie Corrao

Inventor： Kingsley R. Chin ,  Christopher Chang ,  Ernie Corrao

IPC: A61B17/80

CPC classification number: A61B17/1757 ,  A61B17/1622 ,  A61B17/7064 ,  A61B17/7082 ,  A61B17/864 ,  A61B17/8695 ,  A61B2090/036

Abstract: A spinal fixation element includes a screw and a washer. The screw comprises an elongated body of a first diameter and the body includes a threaded portion at a distal end and a semispherical head of a second diameter at a proximal end. The second diameter is larger than the first diameter. The washer comprises a semispherical through opening of a third diameter at the top, of a fourth diameter in the middle and of a fifth diameter at the bottom. The third diameter is slightly smaller than the second diameter, the fourth diameter is slightly larger than the second diameter and the fifth diameter is smaller than the second diameter. The washer surrounds the semispherical head, is non-removably attached to the semispherical head and is rotatable and positionable at an angle relative to the elongated body.

Abstract translation: 脊椎固定元件包括螺钉和垫圈。 螺钉包括第一直径的细长主体，并且主体包括在远端处的螺纹部分和在近端具有第二直径的半球形头部。 第二直径大于第一直径。 垫圈包括在顶部具有第三直径的半球形通孔，在中间具有第四直径，在底部具有第五直径。 第三直径略小于第二直径，第四直径略大于第二直径，第五直径小于第二直径。 垫圈包围半球形头部，不可拆卸地附接到半球形头部，并且可相对于细长主体以一定角度旋转和定位。

公开(公告)号：US08130980B2

公开(公告)日：2012-03-06

申请号：US11766734

申请日：2007-06-21

Applicant: Kok Ghay Wong ,  Thean Kuie Christopher Chang ,  Chee Sin Cheah ,  Huoy Ru Rachel Koh

Inventor： Kok Ghay Wong ,  Thean Kuie Christopher Chang ,  Chee Sin Cheah ,  Huoy Ru Rachel Koh

IPC: H03G3/00

CPC classification number: H04R5/04 ,  H03G1/007 ,  H03G3/3015 ,  H03G7/004

Abstract: There is provided an automatic gain control circuit for volume control receiving at least one audio signal input via either a wired connection or a wireless connection. The circuit includes an output signal regulator receiving a first portion of the at least one audio signal input, with the regulator being able to vary an amplitude of the first portion of the at least one audio signal input when a control signal from a circuit controller is received. The circuit controller may be powered by a DC generator; with the DC generator receiving a second portion of the at least one audio signal input. A signal from the output signal regulator may be passed through an acoustic generator. It is preferable that the first portion of the at least one audio signal input is substantially more than the second portion. It is also preferable that the output signal regulator varies the amplitude of the at least one audio signal input by reducing the amplitude. A corresponding method of volume control is also disclosed.

Abstract translation: 提供了一种用于音量控制的自动增益控制电路，其经由有线连接或无线连接接收至少一个音频信号输入。 所述电路包括接收所述至少一个音频信号输入的第一部分的输出信号调节器，当来自电路控制器的控制信号是来自所述至少一个音频信号输入的控制信号时，所述调节器能够改变所述至少一个音频信号输入的所述第一部分的幅度 收到了 电路控制器可以由直流发电机供电; 所述DC发生器接收所述至少一个音频信号输入的第二部分。 来自输出信号调节器的信号可以通过声发生器。 优选地，至少一个音频信号输入的第一部分基本上大于第二部分。 还优选地，输出信号调节器通过减小振幅来改变至少一个音频信号输入的幅度。 还公开了相应的音量控制方法。

公开(公告)号：US20100177920A1

公开(公告)日：2010-07-15

申请号：US12526507

申请日：2007-02-07

Applicant: Xiao Xiang Shen ,  Thean Kuie Christopher Chang

Inventor： Xiao Xiang Shen ,  Thean Kuie Christopher Chang

IPC: H04R1/02

CPC classification number: H04R9/06

Abstract: There is provided multiple embodiments of a micro-speaker that reproduces audio signals at a low resonant frequency, which correspondingly allows for low frequency reproduction of audio signals by the micro-speaker. The various embodiments of the micro-speaker may enable usage of spiders with larger areas such that mechanical compliance of the spider is increased.

Abstract translation: 提供了以低谐振频率再现音频信号的微型扬声器的多个实施例，其相应地允许微型扬声器对音频信号的低频再现。 微型扬声器的各种实施例可以使得具有较大面积的蜘蛛的使用能够增加蜘蛛的机械依从性。

公开(公告)号：US20080318539A1

公开(公告)日：2008-12-25

申请号：US11766734

申请日：2007-06-21

Applicant: Kok Ghay WONG ,  Thean Kuie Christopher CHANG ,  Chee Sin CHEAH ,  Huoy Ru Rachel KOH

Inventor： Kok Ghay WONG ,  Thean Kuie Christopher CHANG ,  Chee Sin CHEAH ,  Huoy Ru Rachel KOH

IPC: H04B1/16

CPC classification number: H04R5/04 ,  H03G1/007 ,  H03G3/3015 ,  H03G7/004

Abstract: There is provided an automatic gain control circuit for volume control receiving at least one audio signal input via either a wired connection or a wireless connection. The circuit includes an output signal regulator receiving a first portion of the at least one audio signal input, with the regulator being able to vary an amplitude of the first portion of the at least one audio signal input when a control signal from a circuit controller is received. The circuit controller may be powered by a DC generator; with the DC generator receiving a second portion of the at least one audio signal input. A signal from the output signal regulator may be passed through an acoustic generator. It is preferable that the first portion of the at least one audio signal input is substantially more than the second portion. It is also preferable that the output signal regulator varies the amplitude of the at least one audio signal input by reducing the amplitude. A corresponding method of volume control is also disclosed.

Abstract translation: 提供了一种用于音量控制的自动增益控制电路，其经由有线连接或无线连接接收至少一个音频信号输入。 所述电路包括接收所述至少一个音频信号输入的第一部分的输出信号调节器，当来自电路控制器的控制信号是来自所述至少一个音频信号输入的控制信号时，所述调节器能够改变所述至少一个音频信号输入的所述第一部分的幅度 收到了 电路控制器可以由直流发电机供电; 所述DC发生器接收所述至少一个音频信号输入的第二部分。 来自输出信号调节器的信号可以通过声发生器。 优选地，至少一个音频信号输入的第一部分基本上大于第二部分。 还优选地，输出信号调节器通过减小振幅来改变至少一个音频信号输入的幅度。 还公开了相应的音量控制方法。

公开(公告)号：US20050186555A1

公开(公告)日：2005-08-25

申请号：US11039396

申请日：2005-01-19

Applicant: Stephen Lippard ,  Christopher Chang ,  Elizabeth Nolan

Inventor： Stephen Lippard ,  Christopher Chang ,  Elizabeth Nolan

IPC: C07F3/06 ,  C12Q1/00 ,  C12Q1/68 ,  C07D45/02

CPC classification number: C07D405/14 ,  C07D311/78 ,  C07D405/12 ,  C07D493/10

Abstract: The present invention is directed, in part, to naphthofluorescein-based ligands for detection of metal ions, and methods of making and using the same.

Abstract translation: 本发明部分地涉及用于检测金属离子的萘并荧光素基配体及其制备和使用方法。

公开(公告)号：USD500855S1

公开(公告)日：2005-01-11

申请号：US29198571

申请日：2004-01-30

Applicant: Erez Pick ,  Mark Baerenrodt ,  Stanley Thompson ,  Matthew Ibarra ,  Christopher Chang ,  Daniel O'Sullivan

Designer： Erez Pick ,  Mark Baerenrodt ,  Stanley Thompson ,  Matthew Ibarra ,  Christopher Chang ,  Daniel O'Sullivan

公开(公告)号：US11974765B2

公开(公告)日：2024-05-07

申请号：US17158323

申请日：2021-01-26

Applicant: Matthew James Ibarra ,  Christopher Chang

Inventor： Matthew James Ibarra ,  Christopher Chang

IPC: A61B17/24

CPC classification number: A61B17/24

Abstract: A mouth insert for treating nosebleeds includes a main body and a bite tab. The bite tab removably engages the main body and is configured to move up and/or down vertically in order to adjust the height of the device. The main body includes a horizontally extending elongated portion, a center portion extending downward from a bottom surface of the elongated portion, and the center portion has a narrower width than the horizontally extending elongated portion. The elongated portion of the main body is shaped and dimensioned to be inserted into a buccal cavity of a user's mouth and to fit behind the user's upper lip and in front of the user's upper gums, and the center portion is shaped and dimensioned to be positioned only in front of the user's upper front teeth. The bite tab includes a horizontally extending portion and a vertically extending portion and the vertically extending portion is configured to removably engage the center portion of the main body and the horizontally extending portion includes a push-surface used for pushing the device upward in order to provide pressure to the user's nose.

公开(公告)号：US09801732B2

公开(公告)日：2017-10-31

申请号：US12913004

申请日：2010-10-27

Applicant: Kingsley Chin ,  Vito Lore ,  Michael Drnek ,  Christopher Chang

Inventor： Kingsley Chin ,  Vito Lore ,  Michael Drnek ,  Christopher Chang

IPC: A61F2/44 ,  A61F2/46 ,  A61F2/30

CPC classification number: A61F2/4455 ,  A61F2/4611 ,  A61F2002/3008 ,  A61F2002/30131 ,  A61F2002/30135 ,  A61F2002/3082 ,  A61F2002/30904 ,  A61F2002/3092 ,  A61F2002/4475 ,  A61F2002/4627

Abstract: An intervertebral implant assembly includes and inserter tool and an implant having a U-shaped body shaped and dimensioned to be placed between two adjacent vertebras. The U-shaped body comprises a rounded front end, an open back end, first and second elongated components extending from the rounded front end, forming the U-shaped body and ending at the open back end and at least one rigid strut extending from and connecting opposite inner side surfaces of the first and second elongated components. A first through-opening is formed in the space between the front end, the rigid strut and the opposite inner side surfaces of the front portions of the first and second elongated components and a second through-opening is formed in the space between the open back end, the rigid strut and the opposite inner side surfaces of the back portions of the first and second elongated components. The inserter tool comprises a shaft, a middle sleeve and an outer sleeve that work together to attach and lock to the implant.

公开(公告)号：US09042585B2

公开(公告)日：2015-05-26

申请号：US12958198

申请日：2010-12-01

Applicant: Thean Kuie Christopher Chang ,  Hui Ying Alexa Phua

Inventor： Thean Kuie Christopher Chang ,  Hui Ying Alexa Phua

IPC: H04R25/00 ,  H04R1/26 ,  H04R1/10 ,  H04R1/28

CPC classification number: H04R1/26 ,  H04R1/10 ,  H04R1/1016 ,  H04R1/2857 ,  H04R2420/07

Abstract: There is provided a method for optimizing performance of a multi-transducer earpiece, where the multi-transducer earpiece includes a perpendicular flange that partitions the cross sectional area of the acoustic delivery channel in a manner where mixing of signals from both the high frequency transducer and the mid/low frequency transducer is carried out in the ear canal of a user during reproduction of audio signals.

Abstract translation: 提供了一种用于优化多换能器耳机的性能的方法，其中多换能器耳机包括垂直法兰，该垂直凸缘以声音输送通道的横截面积分隔，其方式是混合来自高频换能器和 在再现音频信号期间，中/低频换能器在用户的耳道中进行。