公开(公告)号：US20110305704A1

公开(公告)日：2011-12-15

申请号：US13148252

申请日：2010-02-11

申请人： Mark Pimentel ,  Christopher Chang

发明人： Mark Pimentel ,  Christopher Chang

IPC分类号： A61K39/40 ,  A61P1/00 ,  C07K16/12 ,  G01N33/567 ,  A61K39/02

CPC分类号： G01N33/573 ,  G01N33/6893 ,  G01N2333/24 ,  G01N2333/25 ,  G01N2333/922 ,  G01N2800/065 ,  G01N2800/52

摘要： Methods for preventing IBS, reducing the likelihood of developing IBS and/or treating IBS by administering COT inhibitors and/or COT neutralizers to a subject in need thereof are described. Methods of eliciting a specific immune response and methods of vaccinating a subject to prevent IBS or to reduce the likelihood of developing or having IBS are also provided. Methods of diagnosing IBS by detecting the presence or absence of COT or a COT marker in a subject are described.

摘要翻译： 描述了通过向有需要的受试者施用COT抑制剂和/或COT中和剂来预防IBS，降低发展IBS和/或治疗IBS的可能性的方法。 还提供了引发特异性免疫应答的方法和接种受试者以防止IBS或降低发展或具有IBS的可能性的方法。 描述了通过检测受试者中COT或COT标记物的存在或不存在来诊断IBS的方法。

公开(公告)号：US20110294726A1

公开(公告)日：2011-12-01

申请号：US13148215

申请日：2010-02-11

申请人： Mark Pimentel ,  Christopher Chang

发明人： Mark Pimentel ,  Christopher Chang

IPC分类号： A61K38/12 ,  A61P31/04 ,  A61K31/4164 ,  A61K31/437 ,  A61K31/7036

CPC分类号： A61K31/4188 ,  A61K31/4164 ,  A61K31/437 ,  A61K31/7048 ,  A61K38/14 ,  A61K45/06 ,  Y02A50/47 ,  Y02A50/473 ,  Y02A50/475 ,  Y02A50/481 ,  A61K2300/00

摘要： The present invention provides for methods of preventing IBS, preventing long term irregular bowel pattern, reducing the likelihood of developing or having IBS, reducing the likelihood of developing or having long term irregular bowel pattern, mitigating IBS, mitigating long term irregular bowel pattern and reducing the likelihood of developing non-ulcer dyspepsia. The methods comprise providing an antibiotic and administering the antibiotic to a subject in need thereof.

摘要翻译： 本发明提供了防止IBS，预防长期不规则排尿模式，降低发展或具有IBS的可能性，减少发展或具有长期不规则排泄模式的可能性，减轻IBS，减轻长期不规则排尿模式和减少IBS的方法 发生非溃疡性消化不良的可能性。 所述方法包括提供抗生素并将抗生素施用于有需要的受试者。

公开(公告)号：US09110081B2

公开(公告)日：2015-08-18

申请号：US13148252

申请日：2010-02-11

申请人： Mark Pimentel ,  Christopher Chang

发明人： Mark Pimentel ,  Christopher Chang

IPC分类号： G01N33/53 ,  G01N33/68

CPC分类号： G01N33/573 ,  G01N33/6893 ,  G01N2333/24 ,  G01N2333/25 ,  G01N2333/922 ,  G01N2800/065 ,  G01N2800/52

摘要： Methods for preventing IBS, reducing the likelihood of developing IBS and/or treating IBS by administering COT inhibitors and/or COT neutralizers to a subject in need thereof are described. Methods of eliciting a specific immune response and methods of vaccinating a subject to prevent IBS or to reduce the likelihood of developing or having IBS are also provided. Methods of diagnosing IBS by detecting the presence or absence of COT or a COT marker in a subject are described.

摘要翻译： 描述了通过向有需要的受试者施用COT抑制剂和/或COT中和剂来预防IBS，降低发展IBS和/或治疗IBS的可能性的方法。 还提供了引发特异性免疫应答的方法和接种受试者以防止IBS或降低发展或具有IBS的可能性的方法。 描述了通过检测受试者中COT或COT标记物的存在或不存在来诊断IBS的方法。

公开(公告)号：US08504982B2

公开(公告)日：2013-08-06

申请号：US12651971

申请日：2010-01-04

申请人： Matthew D. Joe ,  Paul C. Currit ,  Minn Thein ,  Sumit Chawla ,  David Mainer ,  Stephen J. Maine ,  Christopher Chang ,  Mei Yuei Lee ,  Kyle F. Huntley ,  Karel Deman ,  Blake M. Dong

发明人： Matthew D. Joe ,  Paul C. Currit ,  Minn Thein ,  Sumit Chawla ,  David Mainer ,  Stephen J. Maine ,  Christopher Chang ,  Mei Yuei Lee ,  Kyle F. Huntley ,  Karel Deman ,  Blake M. Dong

IPC分类号： G06F9/44

CPC分类号： G06F8/20

摘要： An aspect container being operable to generate an instance of itself at run time is provided. The aspect container comprises logic operable to create an instance of the aspect container by reading configuration information specifying a sequence of one or more aspects from an aspect container configuration file corresponding to the aspect container. The logic is also operable to generate instances of the aspects in the sequence, configure each aspect instance with its configuration information from an aspect configuration file corresponding to the aspect, and chain the aspect instances according to the specified sequence, such that the chain of aspect instances preamble and postamble activities of a class or method.

摘要翻译： 提供了可在运行时生成自身实例的方面容器。 方面容器包括可操作以通过从对应于方面容器的方面容器配置文件中读取配置信息来指定一个或多个方面的顺序来创建方面容器的实例的逻辑。 该逻辑还可操作以生成序列中的各方面的实例，使用其配置信息从与该方面相对应的方面配置文件配置每个方面实例，并根据指定的顺序链接方面实例，使得方面的链 类或方法的实例前导和后同步活动。

公开(公告)号：US20100229152A1

公开(公告)日：2010-09-09

申请号：US12616058

申请日：2009-11-10

申请人： Matthew D. Joe ,  Paul C. Currit ,  Minn Thein ,  Sumit Chawla ,  David Mainer ,  Stephen J. Maine ,  Christopher Chang ,  Mei Yuei Lee ,  Kyle F. Huntley ,  Karel Deman ,  Blake M. Dong

发明人： Matthew D. Joe ,  Paul C. Currit ,  Minn Thein ,  Sumit Chawla ,  David Mainer ,  Stephen J. Maine ,  Christopher Chang ,  Mei Yuei Lee ,  Kyle F. Huntley ,  Karel Deman ,  Blake M. Dong

IPC分类号： G06F9/45

CPC分类号： G06F9/548 ,  G06F8/30 ,  G06F8/60

摘要： A prescriptive architecture for application development is provided. In some embodiments, the architecture comprises a service, a receiver, a sender, and a transport. The service functions to perform the actual business logic, is decorated with service deployment metadata; and is operable to communicate via types. The receiver is coupled to the service and is generated entirely from the service deployment metadata. The receiver is operable to receive messages, convert the received messages into types, and communicate with the service using the types. The sender is coupled to the receiver and is generated entirely from the service deployment metadata. The sender functions as a proxy for the service to a service consumer, and is operable to communicate using types with the service consumer. The sender is operable to convert the types to messages, and communicate with the receiver via messages. The transport functions as a message exchange technology that allows the sender and receiver to communicate, and is designated by the service deployment metadata and implemented as an underlying technology of the sender and the receiver.

摘要翻译： 提供了一个用于应用程序开发的规范性架构。 在一些实施例中，架构包括服务，接收器，发送器和传输。 用于执行实际业务逻辑的服务功能用服务部署元数据进行装饰; 并且可操作以经由类型进行通信。 接收器被耦合到服务并且完全由服务部署元数据生成。 接收器可操作以接收消息，将接收到的消息转换成类型，并使用这些类型与服务进行通信。 发送方耦合到接收方，并且完全由服务部署元数据生成。 发件人作为服务的代理人服务于消费者，并且可操作地使用与服务消费者的类型进行通信。 发送者可操作地将类型转换成消息，并通过消息与接收者进行通信。 传输功能作为消息交换技术，允许发送方和接收方进行通信，并由服务部署元数据指定并实现为发送方和接收方的基础技术。

公开(公告)号：US07265588B2

公开(公告)日：2007-09-04

申请号：US11205668

申请日：2005-08-17

申请人： Christopher Chang ,  Jeffrey Lewis Parker

发明人： Christopher Chang ,  Jeffrey Lewis Parker

IPC分类号： H03K19/00

CPC分类号： G06F1/08 ,  G06F1/324 ,  Y02D10/126

摘要： A clock change circuit includes enabling a clock change frequency to be accepted while a system is active and clock frequencies are at a low period. The circuit includes generating an enabling signal representing a window of time in which a frequency change is accomplished.

摘要翻译： 时钟变换电路包括在系统有效并且时钟频率处于低周期时允许接收时钟变化频率。 电路包括产生表示实现频率变化的时间窗口的使能信号。

公开(公告)号：US20070012657A1

公开(公告)日：2007-01-18

申请号：US11525102

申请日：2006-09-22

申请人： Robert O'Donnell ,  Christopher Chang ,  John Daugherty

发明人： Robert O'Donnell ,  Christopher Chang ,  John Daugherty

IPC分类号： C30B33/00 ,  C23F1/00 ,  H01L21/306 ,  B44C1/22

CPC分类号： H01J37/32467 ,  H01J37/32477 ,  H01J37/32559

摘要： A corrosion resistant component of a plasma chamber includes a liquid crystalline polymer. In a preferred embodiment, the liquid crystalline polymer (LCP) is provided on an aluminum component having an anodized or non-anodized surface. The liquid crystalline polymer can also be provided on an alumina component. The liquid crystalline polymer can be deposited by a method such as plasma spraying. The liquid crystalline polymer may also be provided as a preformed sheet or other shape adapted to cover the exposed surfaces of the reaction chamber. Additionally, the reactor components may be made entirely from liquid crystalline polymer by machining the component from a solid block of liquid crystalline polymer or molding the component from the polymer. The liquid crystalline polymer may contain reinforcing fillers such as glass or mineral fillers.

摘要翻译： 等离子体室的耐腐蚀组分包括液晶聚合物。 在优选的实施方案中，液晶聚合物（LCP）设置在具有阳极氧化或非阳极氧化表面的铝组分上。 液晶聚合物也可以提供在氧化铝组分上。 液晶聚合物可以通过诸如等离子喷涂的方法沉积。 液晶聚合物也可以被提供为预成型片或适于覆盖反应室暴露表面的其它形状。 此外，反应器组分可以通过从液晶聚合物的固体块中加工组分或从聚合物模塑组分而完全由液晶聚合物制成。 液晶聚合物可以含有增强填料如玻璃或矿物填料。

公开(公告)号：US11974765B2

公开(公告)日：2024-05-07

申请号：US17158323

申请日：2021-01-26

申请人： Matthew James Ibarra ,  Christopher Chang

发明人： Matthew James Ibarra ,  Christopher Chang

IPC分类号： A61B17/24

CPC分类号： A61B17/24

摘要： A mouth insert for treating nosebleeds includes a main body and a bite tab. The bite tab removably engages the main body and is configured to move up and/or down vertically in order to adjust the height of the device. The main body includes a horizontally extending elongated portion, a center portion extending downward from a bottom surface of the elongated portion, and the center portion has a narrower width than the horizontally extending elongated portion. The elongated portion of the main body is shaped and dimensioned to be inserted into a buccal cavity of a user's mouth and to fit behind the user's upper lip and in front of the user's upper gums, and the center portion is shaped and dimensioned to be positioned only in front of the user's upper front teeth. The bite tab includes a horizontally extending portion and a vertically extending portion and the vertically extending portion is configured to removably engage the center portion of the main body and the horizontally extending portion includes a push-surface used for pushing the device upward in order to provide pressure to the user's nose.

公开(公告)号：US09801732B2

公开(公告)日：2017-10-31

申请号：US12913004

申请日：2010-10-27

申请人： Kingsley Chin ,  Vito Lore ,  Michael Drnek ,  Christopher Chang

发明人： Kingsley Chin ,  Vito Lore ,  Michael Drnek ,  Christopher Chang

IPC分类号： A61F2/44 ,  A61F2/46 ,  A61F2/30

CPC分类号： A61F2/4455 ,  A61F2/4611 ,  A61F2002/3008 ,  A61F2002/30131 ,  A61F2002/30135 ,  A61F2002/3082 ,  A61F2002/30904 ,  A61F2002/3092 ,  A61F2002/4475 ,  A61F2002/4627

摘要： An intervertebral implant assembly includes and inserter tool and an implant having a U-shaped body shaped and dimensioned to be placed between two adjacent vertebras. The U-shaped body comprises a rounded front end, an open back end, first and second elongated components extending from the rounded front end, forming the U-shaped body and ending at the open back end and at least one rigid strut extending from and connecting opposite inner side surfaces of the first and second elongated components. A first through-opening is formed in the space between the front end, the rigid strut and the opposite inner side surfaces of the front portions of the first and second elongated components and a second through-opening is formed in the space between the open back end, the rigid strut and the opposite inner side surfaces of the back portions of the first and second elongated components. The inserter tool comprises a shaft, a middle sleeve and an outer sleeve that work together to attach and lock to the implant.

公开(公告)号：US20130084930A1

公开(公告)日：2013-04-04

申请号：US13248445

申请日：2011-09-29

申请人： Christopher Chang ,  Steven Byrne ,  Katrina Lane ,  Thomas Rassweiler ,  Kenny Rosenblatt

发明人： Christopher Chang ,  Steven Byrne ,  Katrina Lane ,  Thomas Rassweiler ,  Kenny Rosenblatt

IPC分类号： A63F9/24

CPC分类号： G07F17/32 ,  G07F17/3295 ,  G07F17/38

摘要： Described are casino games that incorporate a player's physical dexterity into gameplay, thus adding a physical skill component to a game, beyond any mental skill components the underlying games already posses. Similarly to the manner in which a player's knowledge of a game's rules and strategies allows the player to increase their chance of winning traditional casino games, the dexterity, or skill based games allow the player to increase their chance of winning by performing game-oriented physical tasks. Examples of games with this feature are a poker game where a player shoots a game gun at a display device to add cards to their hand in hopes of forming a winning hand, and a three dimensional mahjong game where a player rotates a tile structure to find and removing matching tiles in order to increase their score.

摘要翻译： 描述的是娱乐场游戏，其将玩家的物理灵巧性融入到游戏中，从而将游戏的身体技能组件添加到基础游戏已经拥有的任何精神技能组件之外。 类似于玩家对游戏规则和策略的了解的方式允许玩家增加获得传统赌场游戏的机会，灵巧或基于技能的游戏允许玩家通过执行游戏导向的物理来增加获胜的机会 任务。 具有该特征的游戏的示例是扑克游戏，其中玩家在显示设备上拍摄游戏枪以向他们的手中添加卡以希望形成获胜的手，以及三维麻将游戏，其中玩家旋转瓦片结构以找到 并删除匹配的图块以增加他们的分数。