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公开(公告)号：US20130005729A1
公开(公告)日：2013-01-03
申请号：US13527402
申请日：2012-06-19
申请人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
IPC分类号： A61K31/4439 , C12N9/99 , C07D401/14 , A61K31/506 , C07D413/14 , A61K31/5377 , C07D413/06 , C07D417/06 , C07D409/14 , A61K31/444 , A61P31/10 , A61P29/00 , A61P35/00 , A61P9/00 , A61P27/02 , A61P3/00 , A61P25/00 , A61P1/00 , A61P15/00 , C07D401/06
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US08809378B2
公开(公告)日：2014-08-19
申请号：US13527387
申请日：2012-06-19
申请人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20120329788A1
公开(公告)日：2012-12-27
申请号：US13527426
申请日：2012-06-19
申请人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号： A01N43/713 , C07D401/14 , C07D417/14 , C07D409/14 , A01N43/653 , A01N43/88 , A01N43/54 , A01P3/00 , C07D401/06 , A01N43/78
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US08901121B2
公开(公告)日：2014-12-02
申请号：US13527402
申请日：2012-06-19
申请人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger
IPC分类号： A61K31/535 , A61K31/44 , C07D239/42 , C07D413/08 , C07D401/08 , C07D403/08 , A01N43/713 , A01N43/54 , C07D417/06 , A01N43/647 , A01N43/76 , C07D409/14 , C07D405/06 , C07D401/14 , C07D401/06 , C07D413/06 , A01N43/78 , A01N43/56
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US08796001B2
公开(公告)日：2014-08-05
申请号：US13527413
申请日：2012-06-19
申请人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger
IPC分类号： A61K31/505 , A61K31/44 , A61K31/655 , A61K31/47 , C12N9/99 , C07D239/02 , C07D401/08 , C07D215/12 , C07D417/08 , C07D413/08
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20130005752A1
公开(公告)日：2013-01-03
申请号：US13527413
申请日：2012-06-19
申请人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger
IPC分类号： A61K31/4439 , C12N9/99 , C07D401/14 , A61K31/444 , C07D417/14 , A61K31/506 , A61K31/4709 , A61P31/10 , A61P1/00 , A61P29/00 , A61P15/00 , A61P27/02 , A61P9/00 , A61P35/00 , C07D401/06
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20220081420A1
公开(公告)日：2022-03-17
申请号：US17421567
申请日：2020-01-08
IPC分类号： C07D403/04 , C07D471/04 , C07D519/00 , A61K45/06
摘要： Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20180256572A1
公开(公告)日：2018-09-13
申请号：US15917555
申请日：2018-03-09
申请人： Christopher M. Yates
发明人： Christopher M. Yates
IPC分类号： A61K31/506
CPC分类号： A61K31/506 , C07D413/04 , C07D413/14
摘要： Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
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公开(公告)号：US08748461B2
公开(公告)日：2014-06-10
申请号：US13527426
申请日：2012-06-19
申请人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
发明人： William J. Hoekstra , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Zachary A. Buchan , Michael T. Sullenberger , Gary D. Gustafson
CPC分类号： A01N43/713 , A01N25/00 , A01N43/647 , A01N43/653 , A01N43/78 , C07D401/06 , C07D401/14 , C07D409/14 , C07D417/14
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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公开(公告)号：US20130005719A1
公开(公告)日：2013-01-03
申请号：US13527387
申请日：2012-06-19
申请人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
发明人： William J. Hoekstra , Stephen W. Rafferty , Christopher M. Yates , Robert J. Schotzinger , Michael R. Loso , Michael T. Sullenberger , Gary D. Gustafson
IPC分类号： A01N43/40 , C07D401/14 , A01N43/54 , A01N43/88 , A01N43/84 , A01P1/00 , A01P3/00 , C07D401/06 , C07D413/14
CPC分类号： C07D401/06 , A01N43/54 , A01N43/56 , A01N43/647 , A01N43/653 , A01N43/713 , A01N43/76 , A01N43/78 , A01N43/84 , C07D401/14 , C07D405/06 , C07D409/14 , C07D413/06 , C07D417/06
摘要： The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
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