APPARATUS FOR MEASURING PERFUSION RATE OF LEGS
    1.
    发明申请
    APPARATUS FOR MEASURING PERFUSION RATE OF LEGS 审中-公开
    用于测量LEGS灌注速率的装置

    公开(公告)号:US20080221421A1

    公开(公告)日:2008-09-11

    申请号:US11955817

    申请日:2007-12-13

    CPC classification number: A61B5/0261 A61B5/0275

    Abstract: The present invention relates to an apparatus for measuring the perfusion rate of legs. The measurement apparatus of the present invention includes a light leakage prevention unit including a light emitting device for radiating light having a certain wavelength onto a living body injected with Indocyanine Green (ICG), and a light leakage prevention housing formed to prevent transmission of external light. A data acquisition unit includes a band pass filter for passing therethrough only light, having a near infrared wavelength, in a fluorescence image emitted by the ICG and the light emitting device, and a Charge Coupled Device (CCD) camera for photographing a near infrared wavelength region. A data processing unit calculates a perfusion rate of the living body on a basis of data about the near infrared wavelength region through a data cable connected to the data acquisition unit. A data output unit outputs the perfusion rate calculated by the data processing unit.

    Abstract translation: 本发明涉及一种用于测量腿部灌注速率的装置。 本发明的测量装置包括防漏单元,其包括用于将具有一定波长的光发射到注射有吲哚菁绿(ICG)的生物体上的发光装置和防止外部光透射的防漏壳 。 数据采集​​单元包括带通滤波器,其仅通过ICG和发光器件发射的荧光图像中的具有近红外波长的光,以及用于拍摄近红外波长的电荷耦合器件(CCD) 地区。 数据处理单元通过与数据采集单元连接的数据电缆,基于近红外线波长区域的数据计算生物体的灌注速度。 数据输出单元输出由数据处理单元计算的灌注速率。

    Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same
    4.
    发明授权
    Modulator of vascular permeability using pulsed laser and method for modulating vascular permeability using the same 有权
    使用脉冲激光的血管通透性调节剂及其调节血管通透性的方法

    公开(公告)号:US08483819B2

    公开(公告)日:2013-07-09

    申请号:US12785155

    申请日:2010-05-21

    Abstract: Disclosed herein is a modulator of vascular permeability using pulsed laser and a method for modulating vascular permeability using the same. More specifically, because the pulsed laser effectively induces vascular permeabilization, effectively delivers intravascular materials into tissues and minimizes insult to the tissues by the induced vascular permeabilization, and locally targets a subcutaneous tissue for noninvasive modulation due to its nonlinearity, it may be usefully used for modulation of permeability.

    Abstract translation: 本文公开了使用脉冲激光的血管通透性的调节剂和使用其调节血管通透性的方法。 更具体地说,因为脉冲激光有效地诱导血管透化,有效地将血管内物质输送到组织中并且通过诱导的血管透化最小化对组织的侮辱,并且由于其非线性而局部地将皮下组织靶向用于非侵入性调节,所以可以有用地用于 调节渗透性。

    SYSTEM FOR ANALYZING TISSUE PERFUSION USING CONCENTRATION OF INOCYANINE GREEN IN BLOOD
    5.
    发明申请
    SYSTEM FOR ANALYZING TISSUE PERFUSION USING CONCENTRATION OF INOCYANINE GREEN IN BLOOD 失效
    使用浓度浓度的绿色荧光的组织分析系统

    公开(公告)号:US20100036217A1

    公开(公告)日:2010-02-11

    申请号:US12445212

    申请日:2007-07-11

    CPC classification number: A61B5/0261 A61B5/0059 A61B5/0275

    Abstract: The present invention relates, in general, to a system for analyzing tissue perfusion using the concentration of indocyanine green and a method of measuring the perfusion rate using the system and, more particularly, to a system for measuring tissue perfusion by injecting indocyanine green into a living body, detecting variation in the concentration of indocyanine green with the passage of time, and analyzing the detected variation, and a method of measuring the perfusion rate using the system. The present invention provides a method of measuring perfusion in a living body, which enables accurate measurement for respective regions in a wide range from a perfusion rate decreased to less than 10% of normal perfusion to a perfusion rate increased to greater than normal perfusion using the above-described mechanism of ICG in a living body, which cannot be conducted using the conventional technology.

    Abstract translation: 本发明一般涉及使用吲哚青绿的浓度来分析组织灌注的系统和使用该系统测量灌注速率的方法,更具体地,涉及通过将吲哚青绿注入到组织灌注中来测量组织灌注的系统 生物体,随着时间的推移检测吲哚青绿浓度的变化,分析检测到的变异,以及使用该系统测量灌注速率的方法。 本发明提供了一种测量生物体中的灌注的方法,其能够在从正常灌注的灌注速率降低到小于10%的灌注速率的范围内的各个区域的精确测量到使用 ICG在生物体中的上述机理,其不能用传统技术进行。

    System for analyzing tissue perfusion using concentration of indocyanine green in blood
    6.
    发明授权
    System for analyzing tissue perfusion using concentration of indocyanine green in blood 失效
    血液中吲哚青绿浓度分析组织灌注系统

    公开(公告)号:US08285353B2

    公开(公告)日:2012-10-09

    申请号:US12445212

    申请日:2007-07-11

    CPC classification number: A61B5/0261 A61B5/0059 A61B5/0275

    Abstract: The present invention relates, in general, to a system for analyzing tissue perfusion using the concentration of indocyanine green and a method of measuring the perfusion rate using the system and, more particularly, to a system for measuring tissue perfusion by injecting indocyanine green into a living body, detecting variation in the concentration of indocyanine green with the passage of time, and analyzing the detected variation, and a method of measuring the perfusion rate using the system. The present invention provides a method of measuring perfusion in a living body, which enables accurate measurement for respective regions in a wide range from a perfusion rate decreased to less than 10% of normal perfusion to a perfusion rate increased to greater than normal perfusion using the above-described mechanism of ICG in a living body, which cannot be conducted using the conventional technology.

    Abstract translation: 本发明一般涉及使用吲哚青绿的浓度来分析组织灌注的系统和使用该系统测量灌注速率的方法,更具体地,涉及通过将吲哚青绿注入到组织灌注中来测量组织灌注的系统 生物体,随着时间的推移检测吲哚青绿浓度的变化,分析检测到的变异,以及使用该系统测量灌注速率的方法。 本发明提供了一种测量生物体中的灌注的方法,其能够在从正常灌注的灌注速率降低到小于10%的灌注速率的范围内的各个区域的精确测量到使用 ICG在生物体中的上述机理,其不能用传统技术进行。

    MODULATOR OF VASCULAR PERMEABILITY USING PULSED LASER AND METHOD FOR MODULATING VASCULAR PERMEABILITY USING THE SAME
    7.
    发明申请
    MODULATOR OF VASCULAR PERMEABILITY USING PULSED LASER AND METHOD FOR MODULATING VASCULAR PERMEABILITY USING THE SAME 有权
    使用脉冲激光的血管渗透性的调节剂和使用其调节血管渗透性的方法

    公开(公告)号:US20110152744A1

    公开(公告)日:2011-06-23

    申请号:US12785155

    申请日:2010-05-21

    Abstract: Disclosed herein is a modulator of vascular permeability using pulsed laser and a method for modulating vascular permeability using the same. More specifically, because the pulsed laser effectively induces vascular permeabilization, effectively delivers intravascular materials into tissues and minimizes insult to the tissues by the induced vascular permeabilization, and locally targets a subcutaneous tissue for noninvasive modulation due to its nonlinearity, it may be usefully used for modulation of permeability.

    Abstract translation: 本文公开了使用脉冲激光的血管通透性的调节剂和使用其调节血管通透性的方法。 更具体地说,因为脉冲激光有效地诱导血管透化,有效地将血管内物质输送到组织中并且通过诱导的血管透化最小化对组织的侮辱,并且由于其非线性而局部地将皮下组织靶向用于非侵入性调节,所以可以有用地用于 调节渗透性。

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