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公开(公告)号：US10702614B2
公开(公告)日：2020-07-07
申请号：US13985087
申请日：2012-02-03
IPC分类号： A61K51/12
摘要： A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides so as to treat the tumor in the subject, or so as to reduce or prevent metastasis of the tumor in the subject. Radiobacteria-containing compositions and pharmaceutical compositions are also provided.
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公开(公告)号：US20070264279A1
公开(公告)日：2007-11-15
申请号：US11727889
申请日：2007-03-28
申请人： Claudia Gravekamp , Yvonne Paterson , Paulo Maciag
发明人： Claudia Gravekamp , Yvonne Paterson , Paulo Maciag
CPC分类号： A61K39/02 , A61K39/0011 , A61K2039/523 , A61K2039/53 , A61K2039/6068 , C07K14/195 , C07K14/4748 , C07K2319/00
摘要： The present invention provides MAGE-b peptides, recombinant polypeptides comprising same, recombinant nucleotide molecules encoding same, recombinant Listeria strains comprising same, and immunogenic and therapeutic methods utilizing same.
摘要翻译： 本发明提供MAGE-b肽，包含其的重组多肽，编码其的重组核苷酸分子，包含其的重组利斯特氏菌菌株，以及利用其的免疫原性和治疗方法。
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公开(公告)号：US20140147379A1
公开(公告)日：2014-05-29
申请号：US13985087
申请日：2012-02-03
IPC分类号： A61K51/12
CPC分类号： A61K51/1203
摘要： A method of treating a tumor in a subject, or reducing or preventing metastasis of a tumor in a subject, is provided comprising administering to the subject an amount of a bacteria labelled with, or comprising, one or more radionuclides so as to treat the tumor in the subject, or so as to reduce or prevent metastasis of the tumor in the subject. Radiobacteria-containing compositions and pharmaceutical compositions are also provided.
摘要翻译： 提供了治疗受试者中的肿瘤或减少或预防受试者的肿瘤转移的方法，包括向受试者施用一定数量的用一种或多种放射性核素标记或包含一种或多种放射性核素的细菌，以治疗肿瘤 在受试者中，或者以减少或预防受试者中肿瘤的转移。 还提供了含放射性细菌的组合物和药物组合物。
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