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公开(公告)号:US20140106395A1
公开(公告)日:2014-04-17
申请号:US14002269
申请日:2012-03-02
申请人: Christof Fattinger , Patrick Iaiza , Tom Kissling , Dieter Voegelin , Thomas Zumstein , Claudia Mcginnis
发明人: Christof Fattinger , Patrick Iaiza , Tom Kissling , Dieter Voegelin , Thomas Zumstein , Claudia Mcginnis
IPC分类号: G01N33/50
CPC分类号: G01N33/5014 , B01L3/06 , B01L3/50853 , B01L3/5088 , B01L2300/042 , B01L2300/047 , B01L2300/0829 , C12M23/12 , C12M25/01
摘要: A hanging droplet plate (1) comprises a predetermined number of droplet compartments (10) each being capable of receiving a droplet of a liquid. The respective droplet compartment (10) comprises a circumferential microfluidic wetting barrier (102) which is arranged to surround a respective cavity (100) and which prevents a droplet from spreading beyond the microfluidic wetting barrier (102). The respective compartment (10) comprises a closed bottom (101) and at least one additional circumferential microfluidic wetting barrier (104), each additional circumferential microfluidic wetting barrier (104) which is arranged to surround a preceding circumferential microfluidic wetting barrier (102). A wettable area (103) is arranged between two adjacently arranged microfluidic wetting barriers (102, 104).
摘要翻译: 悬挂的液滴板(1)包括预定数量的液滴隔室(10),每个液滴隔室(10)能够接收液滴。 相应的液滴隔室(10)包括周向微流体润湿屏障(102),其被布置成围绕相应的空腔(100)并且防止液滴扩散到微流体润湿屏障(102)之外。 相应的隔室(10)包括封闭的底部(101)和至少一个附加的周向微流体润湿屏障(104),每个附加的周向微流体润湿屏障(104)被布置成围绕先前的周向微流体润湿屏障(102)。 可湿性区域(103)布置在两个相邻布置的微流体润湿屏障(102,104)之间。
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公开(公告)号:US09267933B2
公开(公告)日:2016-02-23
申请号:US14002269
申请日:2012-03-02
申请人: Christof Fattinger , Patrick Iaiza , Tom Kissling , Dieter Voegelin , Thomas Zumstein , Claudia Mcginnis
发明人: Christof Fattinger , Patrick Iaiza , Tom Kissling , Dieter Voegelin , Thomas Zumstein , Claudia Mcginnis
CPC分类号: G01N33/5014 , B01L3/06 , B01L3/50853 , B01L3/5088 , B01L2300/042 , B01L2300/047 , B01L2300/0829 , C12M23/12 , C12M25/01
摘要: A hanging droplet plate (1) comprises a predetermined number of droplet compartments (10) each being capable of receiving a droplet of a liquid. The respective droplet compartment (10) comprises a circumferential microfluidic wetting barrier (102) which is arranged to surround a respective cavity (100) and which prevents a droplet from spreading beyond the microfluidic wetting barrier (102). The respective compartment (10) comprises a closed bottom (101) and at least one additional circumferential microfluidic wetting barrier (104), each additional circumferential microfluidic wetting barrier (104) which is arranged to surround a preceding circumferential microfluidic wetting barrier (102). A wettable area (103) is arranged between two adjacently arranged microfluidic wetting barriers (102, 104).
摘要翻译: 悬挂的液滴板(1)包括预定数量的液滴隔室(10),每个液滴隔室(10)能够接收液滴。 相应的液滴隔室(10)包括周向微流体润湿屏障(102),其被布置成围绕相应的空腔(100)并且防止液滴扩散到微流体润湿屏障(102)之外。 相应的隔室(10)包括封闭的底部(101)和至少一个附加的周向微流体润湿屏障(104),每个附加的周向微流体润湿屏障(104)被布置成围绕先前的周向微流体润湿屏障(102)。 可湿性区域(103)布置在两个相邻布置的微流体润湿屏障(102,104)之间。
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公开(公告)号:US20080096770A1
公开(公告)日:2008-04-24
申请号:US11718298
申请日:2005-10-27
申请人: Claudia McGinnis , Frank Stadtler , Peter Grass , Daniel Bauer
发明人: Claudia McGinnis , Frank Stadtler , Peter Grass , Daniel Bauer
IPC分类号: C40B30/06
CPC分类号: G01N33/5014 , C12Q1/6809 , C12Q1/6876 , C12Q2600/142 , C12Q2600/158
摘要: The invention provides a rapid high throughput screening process to identify genotoxic compounds. This is accomplished by using a set of biomarker predictor genes that selectively screen for genotoxic or non-genotoxic compounds.
摘要翻译: 本发明提供快速高通量筛选方法来鉴定遗传毒性化合物。 这是通过使用一组选择性筛选遗传毒性或非遗传毒性化合物的生物标志物预测基因来实现的。
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