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公开(公告)号：US08317823B2
公开(公告)日：2012-11-27
申请号：US12109574
申请日：2008-04-25
申请人： Dusan Pavcnik , John Kaufman , Clay D. Fette
发明人： Dusan Pavcnik , John Kaufman , Clay D. Fette
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00234 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1219 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61F2/07 , A61F2/89 , A61F6/225 , A61F6/24 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/005
摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。
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公开(公告)号：US07914567B2
公开(公告)日：2011-03-29
申请号：US10719415
申请日：2003-11-21
IPC分类号： A61F2/06
CPC分类号： A61L27/3633 , A61F2/07 , A61F2/852 , A61F2/89 , A61F2/91 , A61F2/95 , A61F2002/065 , A61F2002/075 , A61F2230/0054 , A61F2250/0063 , A61L27/3629
摘要： A stent tissue graft prosthesis (20) for repairing, excluding and/or reinforcing a vessel, duct and the like in a patient. The prosthesis includes an inner expandable stent (21) of which a tissue graft (24) and preferably a multilayered tissue construct (33) is disposed thereon for application to the host tissue of a vessel, duct and the like. The tissue construct includes an extracellular matrix material (36) such as small intestine submucosa (37) for remodeling the host tissue into the prosthesis. The prosthesis further includes an outer tubular member (25) such as an outer expandable stent (44) for retaining the tissue graft on the inner stent. The ends of the inner and outer stents are coincident with or extend beyond the ends of the tissue graft to prevent eversion or fold back of the tissue graft during withdrawal of a delivery catheter in a placement procedure.
摘要翻译： 一种用于在患者体内修复，排除和/或加强血管，导管等的支架组织移植假体（20）。 假体包括内部可扩张支架（21），其上设置有组织移植物（24）并且优选地多层组织构建体（33），用于施加到血管，导管等的宿主组织。 组织构建体包括细胞外基质材料（36），例如用于将宿主组织重塑成假体的小肠粘膜下层（37）。 假体还包括外部管状构件（25），例如用于将组织移植物保持在内部支架上的外部可扩张支架（44）。 内部和外部支架的端部与组织移植物的端部重合或延伸超过组织移植物的端部，以防止在放置过程中递送导管撤出期间组织移植物的外翻或折回。
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公开(公告)号：US20140148839A1
公开(公告)日：2014-05-29
申请号：US13686569
申请日：2012-11-27
申请人： Dusan Pavcnik , John Kaufman , Clay D. Fette
发明人： Dusan Pavcnik , John Kaufman , Clay D. Fette
IPC分类号： A61B17/12
CPC分类号： A61B17/12131 , A61B17/00234 , A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1219 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61F2/07 , A61F2/89 , A61F6/225 , A61F6/24 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/005
摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。
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公开(公告)号：US08465516B2
公开(公告)日：2013-06-18
申请号：US10843990
申请日：2004-05-12
申请人： Dusan Pavcnik , John Kaufman , Clay D. Fette
发明人： Dusan Pavcnik , John Kaufman , Clay D. Fette
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/00234 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1219 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61F2/07 , A61F2/89 , A61F6/225 , A61F6/24 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/005
摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。
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公开(公告)号：US07691140B2
公开(公告)日：2010-04-06
申请号：US10843816
申请日：2004-05-12
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B17/0644 , A61B2017/00252 , A61B2017/00867 , A61B2017/1107 , A61B2017/1135 , A61F2/064 , A61F2/848 , A61F2/86 , A61F2/89 , A61F2002/8483 , A61F2220/0008 , A61F2220/0016 , A61F2220/005 , A61F2230/005
摘要： An anastomosis device (12) for advantageously bridging an artery and a vein. The anastomosis device includes a tubular graft (15) with first and second ends (47 and 48) and a longitudinal passageway extending longitudinally through the graft. The device further includes a first stent (10) disposed about the first end of the tubular graft and a second stent (10) disposed about the second end of the tubular graft. Each of the first and second stents has a plurality of hooks or barbs (11) pointed or releasable to the point toward the other end of the graft.
摘要翻译： 一种用于有利地桥接动脉和静脉的吻合装置（12）。 吻合装置包括具有第一和第二端（47和48）的管状移植物（15）和纵向延伸穿过移植物的纵向通道。 该装置还包括围绕管状移植物的第一端设置的第一支架（10）和围绕管状移植物的第二端设置的第二支架（10）。 第一和第二支架中的每一个具有多个钩或倒钩（11），所述钩或倒钩可指向或可释放到朝向移植物另一端的点。
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公开(公告)号：US20100049246A1
公开(公告)日：2010-02-25
申请号：US12612386
申请日：2009-11-04
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
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7.发明申请公开(公告)号：US20120191216A1
公开(公告)日：2012-07-26
申请号：US13437169
申请日：2012-04-02
IPC分类号： A61F2/02
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。
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8.发明申请公开(公告)号：US20100241162A1
公开(公告)日：2010-09-23
申请号：US12793030
申请日：2010-06-03
CPC分类号： A61B17/0057 , A61B2017/00004 , A61B2017/00641 , A61B2017/00654 , A61M27/00
摘要： Described are devices, methods, and systems useful in the treatment of fistulae, and in certain embodiments those having openings extending into the alimentary canal, such as anorectal fistulae. Illustratively, an anorectal fistula can be treated by placing a volumetric construct within the primary opening of the fistula. In certain embodiments, the volumetric construct can include a rolled remodelable material processed to form a substantially unitary body. Advantageous such remodelable materials can include collagenous extracellular matrix materials, such as small intestine submucosa.
摘要翻译： 描述了可用于治疗瘘的装置，方法和系统，并且在某些实施例中，具有延伸进入消化道的开口的那些，诸如肛门直肠瘘。 说明性地，可以通过将体积结构置于瘘的主要开口内来治疗肛门直肠瘘。 在某些实施方案中，体积构造可以包括经加工以形成基本上单体的卷状可重塑材料。 有益的这种可重塑材料可以包括胶原细胞外基质材料，如小肠粘膜下层。
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公开(公告)号：US20080215087A1
公开(公告)日：2008-09-04
申请号：US12109574
申请日：2008-04-25
申请人： Dusan Pavcnik , John Kaufman , Clay D. Fette
发明人： Dusan Pavcnik , John Kaufman , Clay D. Fette
CPC分类号： A61B17/0057 , A61B17/00234 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/1219 , A61B2017/00004 , A61B2017/00637 , A61B2017/00641 , A61B2017/00654 , A61B2017/00898 , A61F2/07 , A61F2/89 , A61F6/225 , A61F6/24 , A61F2002/061 , A61F2002/065 , A61F2002/077 , A61F2230/005
摘要： An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.
摘要翻译： 一种可吸收和可膨胀的封闭构件，其用于闭塞或排除体腔或腔体，例如血管，输卵管，导管，动脉瘤囊等，其包括封闭构件，该闭合构件包括多个生物材料片材中的一个， 堆叠或折叠以形成大致圆柱形构造的多层构造，用于通过输送系统进行部署，作为单个或多个闭合构件的一部分。 生物材料衍生自源材料，例如小肠粘膜下层或具有用于刺激相邻组织的向内生长进入体内部署的生物材料的特性的另一种可重塑材料（例如细胞外基质）。 封闭构件从输送护套，药筒和/或内部引导构件（例如电线引导件或导管）部署到身体管腔。
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