公开(公告)号：US20070292601A1

公开(公告)日：2007-12-20

申请号：US11566437

申请日：2006-12-04

Applicant: Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim ,  Shengxiong Xiao ,  Matthew Myers

Inventor： Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim ,  Shengxiong Xiao ,  Matthew Myers

IPC: B05D5/12 ,  C07C15/20 ,  C07C43/20 ,  C07C53/44

CPC classification number: H01L51/0048 ,  B82Y10/00 ,  B82Y30/00 ,  C07C15/20 ,  C07C43/2055 ,  C07C43/215 ,  C07C2603/54 ,  H01L51/0049 ,  H01L51/0056 ,  H01L51/05 ,  H01L51/0595

Abstract: The present invention generally relates to the fabrication of molecular electronics devices from molecular wires and Single Wall Nanotubes (SWNT). In one embodiment, the cutting of a SWNT is achieved by opening a window of small width by lithography patterning of a protective layer on top of the SWNT, followed by applying an oxygen plasma to the exposed SWNT portion. In another embodiment, the gap of a cut SWNT is reconnected by one or more difunctional molecules having appropriate lengths reacting to the functional groups on the cut SWNT ends to form covalent bonds. In another embodiment, the gap of a cut SWNT gap is filled with a self-assembled monolayer from derivatives of novel contorted hexabenzocoranenes. In yet another embodiment, a device based on molecular wire reconnected a cut SWNT is used as a sensor to detect a biological binding event.

Abstract translation: 本发明一般涉及从分子线和单壁纳米管（SWNT）制造分子电子器件。 在一个实施例中，通过在SWNT顶部上的保护层的光刻图案化，然后将氧等离子体施加到暴露的SWNT部分，打开小宽度的窗口来实现SWNT的切割。 在另一个实施方案中，切割的SWNT的间隙通过一个或多个具有与切割的SWNT末端上的官能团反应形成共价键的适当长度的双功能分子重新连接。 在另一个实施方案中，切割的SWNT间隙的间隙填充有自组装单层，由新颖扭转的六苯并三硼酸衍生物填充。 在另一个实施方案中，基于重新连接切割SWNT的分子线的装置用作传感器以检测生物结合事件。

公开(公告)号：US20110275062A1

公开(公告)日：2011-11-10

申请号：US12955310

申请日：2010-11-29

Applicant: Xuefeng Guo ,  Colin Nuckolls ,  James Hone ,  Alon Gorodetsky ,  Jacqueline K. Barton

Inventor： Xuefeng Guo ,  Colin Nuckolls ,  James Hone ,  Alon Gorodetsky ,  Jacqueline K. Barton

IPC: C12Q1/68 ,  B05D5/12 ,  C23F1/02 ,  G01R27/28 ,  H01L51/30 ,  G01N33/68 ,  B05D3/00 ,  B82Y99/00

CPC classification number: H01L51/0001 ,  B82Y10/00 ,  G01N27/04 ,  G01N33/5308 ,  G01N33/54373 ,  H01L51/0049 ,  H01L51/0093 ,  H01L51/0595

Abstract: The disclosed subject matter provides a techniques for precisely and/or functionally cutting carbon nanotubes, e.g., single walled carbon nanotubes (“SWNTs”) and integrating a single nucleic acid molecule (e.g., a DNA molecule) into a gap formed into the carbon nanotubes. In one aspect, a method of fabricating a molecular electronic device includes disposing a SWNT on a base layer, forming a gap in the SWNT using a lithographic process, and disposing a single DNA strand across the gap so that each end of the nucleic acid contacts a gap termini. The disclosed subject matter also provides techniques for measuring the electrical properties (charge transport) of a DNA molecule which is integrated into an SWNT. Furthermore, a molecular electronic device including an SWNT with an integrated nucleic acid molecule is disclosed.

Abstract translation: 所公开的主题提供了用于精确和/或功能性地切割碳纳米管的技术，例如单壁碳纳米管（“SWNT”）并将单个核酸分子（例如，DNA分子）整合到形成碳纳米管的间隙中 。 一方面，制造分子电子器件的方法包括在基底层上设置SWNT，使用光刻工艺在SWNT中形成间隙，并且在间隙上设置单个DNA链，使得核酸的每个末端接触 一个差距终点。 所公开的主题还提供了用于测量整合到SWNT中的DNA分子的电特性（电荷转移）的技术。 此外，公开了包含具有整合的核酸分子的SWNT的分子电子器件。

公开(公告)号：US20110168562A1

公开(公告)日：2011-07-14

申请号：US12920817

申请日：2009-03-18

Applicant: Colin Nuckolls ,  Jinyao Tang ,  Stuart Lindsay ,  Jin He ,  Peiming Zhang ,  Kevin Reinhart

Inventor： Colin Nuckolls ,  Jinyao Tang ,  Stuart Lindsay ,  Jin He ,  Peiming Zhang ,  Kevin Reinhart

IPC: G01N27/00 ,  B32B37/24 ,  C23F1/00 ,  B82Y99/00

CPC classification number: G01N33/48721 ,  C12Q1/6869 ,  C12Q2565/631

Abstract: The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.

Abstract translation: 本发明提供一种用于分析包含碳纳米管的杂聚物的组成的装置，通过该电极驱动该杂聚物。 碳纳米管也用作读取电路中的一个电极。 碳纳米管的一端保持靠近第二电极，并且碳纳米管的每一端用柔性系带的化学识别部分功能化，使得将结合新出现的聚合物上的一个位点，而第二个 在另一个位置紧密接合，当通过化学识别过程完成电路时，在两个电极之间产生电信号。

公开(公告)号：US20090027036A1

公开(公告)日：2009-01-29

申请号：US12139207

申请日：2008-06-13

Applicant: Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim ,  Shengxiong Xiao ,  Mathew Benjamin Myers

Inventor： Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim ,  Shengxiong Xiao ,  Mathew Benjamin Myers

IPC: G01N27/00 ,  B05D5/12

CPC classification number: G01N33/5438 ,  B82Y10/00 ,  C12Q1/002 ,  G01N27/128 ,  G01N2610/00 ,  H01L27/285 ,  H01L51/0036 ,  H01L51/0048 ,  H01L51/0056 ,  H01L51/0076 ,  H01L51/0083 ,  H01L51/0591 ,  Y10S977/701 ,  Y10S977/721

Abstract: The present invention generally relates to the fabrication of molecular electronics devices from molecular wires and Single Wall Nanotubes (SWNT). In one embodiment, the cutting of a SWNT is achieved by opening a window of small width by lithography patterning of a protective layer on top of the SWNT, followed by applying an oxygen plasma to the exposed SWNT portion. In another embodiment, the gap of a cut SWNT is reconnected by one or more difunctional molecules having appropriate lengths reacting to the functional groups on the cut SWNT ends to form covalent bonds. In another embodiment, the gap of a cut SWNT gap is filled with a self-assembled monolayer from derivatives of novel contorted hexabenzocoranenes. In yet another embodiment, a device based on molecular wire reconnecting a cut SWNT is used as a sensor to detect a biological binding event.

Abstract translation: 本发明一般涉及从分子线和单壁纳米管（SWNT）制造分子电子器件。 在一个实施例中，通过在SWNT顶部上的保护层的光刻图案化，然后将氧等离子体施加到暴露的SWNT部分，打开小宽度的窗口来实现SWNT的切割。 在另一个实施方案中，切割的SWNT的间隙通过一个或多个具有与切割的SWNT末端上的官能团反应形成共价键的适当长度的双功能分子重新连接。 在另一个实施方案中，切割的SWNT间隙的间隙填充有自组装单层，由新颖扭转的六苯并三硼酸衍生物填充。 在另一个实施例中，使用基于重新连接切割SWNT的分子线的装置作为传感器来检测生物结合事件。

公开(公告)号：US08961757B2

公开(公告)日：2015-02-24

申请号：US12920817

申请日：2009-03-18

Applicant: Colin Nuckolls ,  Jinyao Tang ,  Stuart Lindsay ,  Jin He ,  Peiming Zhang ,  Kevin Reinhart

Inventor： Colin Nuckolls ,  Jinyao Tang ,  Stuart Lindsay ,  Jin He ,  Peiming Zhang ,  Kevin Reinhart

IPC: G01N27/327 ,  C12Q1/68 ,  G01N33/487

CPC classification number: G01N33/48721 ,  C12Q1/6869 ,  C12Q2565/631

Abstract: The present invention provides a device for analyzing the composition of a heteropolymer comprising a carbon nanotube through which the heteropolymer is driven by electrophoresis. The carbon nanotube also serves as one electrode in a reading circuit. One end of the carbon nanotube is held in close proximity to a second electrode, and each end of the carbon nanotube is functionalized with flexibly-tethered chemical-recognition moieties, such that one will bind one site on the emerging polymer, and the second will bind another site in close proximity, generating an electrical signal between the two electrodes when the circuit is completed by the process of chemical recognition.

Abstract translation: 本发明提供一种用于分析包含碳纳米管的杂聚物的组成的装置，通过该电极驱动该杂聚物。 碳纳米管也用作读取电路中的一个电极。 碳纳米管的一端保持靠近第二电极，并且碳纳米管的每一端用柔性系带的化学识别部分功能化，使得将结合新出现的聚合物上的一个位点，而第二个 在另一个位置紧密接合，当通过化学识别过程完成电路时，在两个电极之间产生电信号。

公开(公告)号：US07928432B2

公开(公告)日：2011-04-19

申请号：US12139218

申请日：2008-06-13

Applicant: Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim

Inventor： Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim

IPC: H01L35/24

CPC classification number: G01N33/5438 ,  B82Y10/00 ,  C12Q1/002 ,  G01N27/128 ,  G01N2610/00 ,  H01L27/285 ,  H01L51/0036 ,  H01L51/0048 ,  H01L51/0056 ,  H01L51/0076 ,  H01L51/0083 ,  H01L51/0591 ,  Y10S977/701 ,  Y10S977/721

Abstract: The present invention generally relates to the fabrication of molecular electronics devices from molecular wires and Single Wall Nanotubes (SWNT). In one embodiment, the cutting of a SWNT is achieved by opening a window of small width by lithography patterning of a protective layer on top of the SWNT, followed by applying an oxygen plasma to the exposed SWNT portion. In another embodiment, the gap of a cut SWNT is reconnected by one or more difunctional molecules having appropriate lengths reacting to the functional groups on the cut SWNT ends to form covalent bonds. In another embodiment, the gap of a cut SWNT gap is filled with a self-assembled monolayer from derivatives of novel contorted hexabenzocoranenes. In yet another embodiment, a device based on molecular wire reconnecting a cut SWNT is used as a sensor to detect a biological binding event.

Abstract translation: 本发明一般涉及从分子线和单壁纳米管（SWNT）制造分子电子器件。 在一个实施例中，通过在SWNT顶部上的保护层的光刻图案化，然后将氧等离子体施加到暴露的SWNT部分，打开小宽度的窗口来实现SWNT的切割。 在另一个实施方案中，切割的SWNT的间隙通过一个或多个具有与切割的SWNT末端上的官能团反应形成共价键的适当长度的双功能分子重新连接。 在另一个实施方案中，切割的SWNT间隙的间隙填充有自组装单层，由新颖扭转的六苯并三硼酸衍生物填充。 在另一个实施例中，使用基于重新连接切割SWNT的分子线的装置作为传感器来检测生物结合事件。

公开(公告)号：US20090017571A1

公开(公告)日：2009-01-15

申请号：US12139218

申请日：2008-06-13

Applicant: Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim

Inventor： Colin Nuckolls ,  Xuefeng Guo ,  Philip Kim

IPC: H01L21/00 ,  B01J19/00

CPC classification number: G01N33/5438 ,  B82Y10/00 ,  C12Q1/002 ,  G01N27/128 ,  G01N2610/00 ,  H01L27/285 ,  H01L51/0036 ,  H01L51/0048 ,  H01L51/0056 ,  H01L51/0076 ,  H01L51/0083 ,  H01L51/0591 ,  Y10S977/701 ,  Y10S977/721

Abstract: The present invention generally relates to the fabrication of molecular electronics devices from molecular wires and Single Wall Nanotubes (SWNT). In one embodiment, the cutting of a SWNT is achieved by opening a window of small width by lithography patterning of a protective layer on top of the SWNT, followed by applying an oxygen plasma to the exposed SWNT portion. In another embodiment, the gap of a cut SWNT is reconnected by one or more difunctional molecules having appropriate lengths reacting to the functional groups on the cut SWNT ends to form covalent bonds. In another embodiment, the gap of a cut SWNT gap is filled with a self-assembled monolayer from derivatives of novel contorted hexabenzocoranenes. In yet another embodiment, a device based on molecular wire reconnecting a cut SWNT is used as a sensor to detect a biological binding event.

Abstract translation: 本发明一般涉及从分子线和单壁纳米管（SWNT）制造分子电子器件。 在一个实施例中，通过在SWNT顶部上的保护层的光刻图案化，然后将氧等离子体施加到暴露的SWNT部分，打开小宽度的窗口来实现SWNT的切割。 在另一个实施方案中，切割的SWNT的间隙通过一个或多个具有与切割的SWNT末端上的官能团反应形成共价键的适当长度的双功能分子重新连接。 在另一个实施方案中，切割的SWNT间隙的间隙填充有自组装单层，由新颖扭转的六苯并三硼酸衍生物填充。 在另一个实施例中，使用基于重新连接切割SWNT的分子线的装置作为传感器来检测生物结合事件。