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12 条记录 (耗时 0.013 秒)

    Thiol stimulation of root formation
    2.
    发明授权
    Thiol stimulation of root formation 失效
    硫醇刺激根形成

    公开(公告)号：US5883048A

    公开(公告)日：1999-03-16

    申请号：US886713

    申请日：1997-07-01

    申请人： D. James Morre ,  Guy Auderset ,  Charles Moncousin

    发明人： D. James Morre ,  Guy Auderset ,  Charles Moncousin

    IPC分类号： A01N31/02 ,  A01N37/36 ,  A01N37/44 ,  A01N37/46 ,  A01N47/28 ,  A01N43/38

    CPC分类号： A01N37/36 ,  A01N31/02 ,  A01N37/44 ,  A01N37/46 ,  Y10S47/03

    摘要： Thiol compounds are employed in conjunction with compounds which modulate self proliferation, both as to plants and mammals. The thiol compounds find effect in enhancing the effectiveness of auxin like compounds, either as herbicides or in enhancing root formation. In addition, thiol compounds act in conjunction with cytotoxic agents in mammals to allow for lower dosages of the cytotoxic agents while retaining the cytotoxic effect against hyperproliferative diseases, such as cancer. The combination finds particular effect against cells dependent upon an isoform of a surface membrane NADH oxidase for proliferation.

    摘要翻译： 硫醇化合物与对植物和哺乳动物调节自身增殖的化合物联合使用。 硫醇化合物可以提高生长素样化合物的有效性，作为除草剂或增强根形成。 此外，硫醇化合物与哺乳动物中的细胞毒性剂联合起来以允许更低剂量的细胞毒性剂，同时保留对过度增殖性疾病如癌症的细胞毒性作用。 该组合对依赖于表面膜NADH氧化酶的同种型用于增殖的细胞具有特定的效果。

    Cancer detection by serum analysis of glycolipids
    4.
    发明授权
    Cancer detection by serum analysis of glycolipids 失效
    通过血清分析糖脂进行癌症检测

    公开(公告)号：US4115062A

    公开(公告)日：1978-09-19

    申请号：US805691

    申请日：1977-06-13

    申请人： D. James Morre ,  Thomas M. Kloppel ,  Thomas W. Keenan

    发明人： D. James Morre ,  Thomas M. Kloppel ,  Thomas W. Keenan

    IPC分类号： G01N33/92 ,  G01N33/16

    CPC分类号： G01N33/92

    摘要： In humans and experimental animals, serum levels of sialic acid-containing glycolipids are elevated 1.5 to 3 fold. A method is described whereby the ganglioside content is estimated on as little as 0.5 ml of serum or plasma. The procedure permits, based on the analysis of a single biochemical parameter, cancer detection applicable to a wide range of human and animal tumor types.

    摘要翻译： 在人和实验动物中，含唾液酸糖脂的血清水平升高1.5至3倍。 描述了一种方法，其中神经节苷脂含量估计为少至0.5ml的血清或血浆。 该程序允许基于单个生物化学参数的分析，适用于广泛的人类和动物肿瘤类型的癌症检测。

    Thiol activation of cytotoxic and auxin-herbicidal agents and root formation stimulation
    6.
    发明授权
    Thiol activation of cytotoxic and auxin-herbicidal agents and root formation stimulation 失效
    硫醇活化细胞毒素和生长素除草剂和根形成刺激

    公开(公告)号：US5643853A

    公开(公告)日：1997-07-01

    申请号：US397659

    申请日：1995-02-28

    申请人： D. James Morre

    发明人： D. James Morre

    IPC分类号： A01N31/02 ,  A01N37/36 ,  A01N37/44 ,  A01N37/46 ,  A01N47/28 ,  A01N43/40 ,  A01N37/10 ,  A01N39/02 ,  A01N39/04

    CPC分类号： A01N37/36 ,  A01N31/02 ,  A01N37/44 ,  A01N37/46 ,  Y10S47/03

    摘要： Thiol compounds are employed in conjunction with compounds which modulate self proliferation, both as to plants and mammals. The thiol compounds find effect in enhancing the effectiveness of auxin like compounds, either as herbicides or in enhancing root formation. In addition, thiol compounds act in conjunction with cytotoxic agents in mammals to allow for lower dosages of the cytotoxic agents while retaining the cytotoxic effect against hyperproliferative diseases, such as cancer. The combination finds particular effect against cells dependent upon an isoform of a surface membrane NADH oxidase for proliferation.

    摘要翻译： 硫醇化合物与对植物和哺乳动物调节自身增殖的化合物联合使用。 硫醇化合物可以提高生长素样化合物的有效性，作为除草剂或增强根形成。 此外，硫醇化合物与哺乳动物中的细胞毒性剂联合起来以允许更低剂量的细胞毒性剂，同时保留对过度增殖性疾病如癌症的细胞毒性作用。 该组合对依赖于表面膜NADH氧化酶的同种型用于增殖的细胞具有特定的效果。

    Anticancer Treatment
    7.
    发明申请
    Anticancer Treatment 审中-公开
    抗癌治疗

    公开(公告)号：US20080095869A1

    公开(公告)日：2008-04-24

    申请号：US11660277

    申请日：2005-08-17

    申请人： David Archibald ,  Dorothy Morre ,  D. James Morre

    发明人： David Archibald ,  Dorothy Morre ,  D. James Morre

    IPC分类号： A61K36/00 ,  A61K31/165 ,  A61P35/00

    CPC分类号： A61K36/31 ,  A61K36/81

    摘要： A method of inhibiting tNOX in a living entity which includes administering to the entity, wherein the entity has cancer cells that express tNOX, a therapeutically active amount of a combination of botanicals selected from the groups consisting of cruciferous vegetables and Capsicum plants.

    摘要翻译： 一种在活体中抑制tNOX的方法，其包括向所述实体施用所述实体，所述实体具有表达tNOX的癌细胞，治疗活性量的选自十字花科蔬菜和辣椒植物的植物的组合。

    Compositions and methods for treating and preventing virus infections
    8.
    发明申请
    Compositions and methods for treating and preventing virus infections 有权
    用于治疗和预防病毒感染的组合物和方法

    公开(公告)号：US20070077316A1

    公开(公告)日：2007-04-05

    申请号：US11241744

    申请日：2005-09-30

    申请人： D. James Morre ,  Dorothy M. Morre

    发明人： D. James Morre ,  Dorothy M. Morre

    IPC分类号： A61K36/82 ,  A61K36/81

    CPC分类号： A61K36/81 ,  A61K36/82 ,  Y02A50/387 ,  A61K2300/00

    摘要： Provided are compositions comprising a vanilloid and tea catechins in amounts and proportions which combat virus infections in a human or animal. The vanilloid can be provided in the form of a dried pepper preparation and the tea catechins can be provided in the form of a green tea extract (or concentrate). These active ingredients can be provided separately or in combination. The administration of a such nutritional or other composition, desirably oral administration (in an amount effect) results in reduced virus infection or ameliorated symptoms of virus infection in a human or an animal in need of such a composition.

    摘要翻译： 提供的组合物包含与人或动物中的病毒感染相抗衡的量和比例的香草酸和茶儿茶素。 香草醇可以以干胡椒制剂的形式提供，茶儿茶素可以以绿茶提取物（或浓缩物）的形式提供。 这些活性成分可以单独或组合提供。 施用这样的营养或其它组合物，期望地口服给药（量的作用）导致需要这种组合物的人或动物中病毒感染或病毒感染症状的改善。

    Cloning and Expression of arNOX Protein Transmembrane 9 Superfamily (TM9SF), Methods and Utility
    10.
    发明申请
    Cloning and Expression of arNOX Protein Transmembrane 9 Superfamily (TM9SF), Methods and Utility 审中-公开
    arNOX蛋白跨膜9超家族（TM9SF）的克隆和表达，方法和实用性

    公开(公告)号：US20120315629A1

    公开(公告)日：2012-12-13

    申请号：US13390795

    申请日：2010-08-17

    申请人： D. James Morre ,  Xiaoyu Tang ,  Sara Dick ,  Christiaan Meadows ,  Dorothy M. Morre

    发明人： D. James Morre ,  Xiaoyu Tang ,  Sara Dick ,  Christiaan Meadows ,  Dorothy M. Morre

    IPC分类号： C12N9/02 ,  C12N1/21 ,  C07K16/40 ,  C12N1/19 ,  C12Q1/68 ,  G01N33/573 ,  C12N15/53 ,  C12N5/10

    CPC分类号： G01N33/573 ,  A61K39/00 ,  C12N9/0036 ,  G01N2333/90209

    摘要： Described are cell surface and circulating markers for aging related disorders (specific isoforms of NADH oxidase (arNOX)). Recombinant age-related NADH oxidase isoforms and their coding sequences and methods for detecting arNOX isoform presence and quantitation in tissues and in blood, sera, urine, saliva, perspiration and in other body fluids, are provided. Recombinant arNOX proteins are useful in preparing antigens for use in the generation of monoclonal and polyclonal antibodies as well as immunogenic compositions for diagnosis and treatment of aging disorders. DNA probes based on the DNA sequence information provide may be used to identify individuals at risk for aging disorders and for development of therapeutic interventions or anti-aging cosmetic or other formulations of benefit in slowing the aging process in mammals.

    摘要翻译： 描述了老化相关疾病（NADH氧化酶（arNOX）的特异性同种型））的细胞表面和循环标志物。 提供重组年龄相关的NADH氧化酶同种型及其编码序列和检测组织和血液，血清，尿液，唾液，汗水和其他体液中的arNOX同种型存在和定量的方法。 重组arNOX蛋白质可用于制备用于产生单克隆和多克隆抗体的抗原以及用于诊断和治疗老化障碍的免疫原性组合物。 基于提供的DNA序列信息的DNA探针可用于鉴定处于老化障碍风险中的个体，以及用于开发用于减缓哺乳动物衰老过程的治疗干预或抗衰老化妆品或其它有益的制剂。