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公开(公告)号：US20220387816A1
公开(公告)日：2022-12-08
申请号：US17889115
申请日：2022-08-16
发明人： Thomas BOYAJIAN , Mark CAROTA , Brian MAZEJKA
摘要： An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of first panels or the at least one second panel and configured to irradiate the surface with substantially uniform intensity visible light. The plurality of first panels and the at least one second panel are rotatably connected. The at least one second panel is connected on each side to one of the plurality of first panels. The second panel acts as a “lighted hinge” to reduce or eliminate optical dead spaces between adjacent panels when the illuminator is bent into a certain configuration.
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公开(公告)号：US20210085788A1
公开(公告)日：2021-03-25
申请号：US17109311
申请日：2020-12-02
发明人： Scott LUNDAHL , Michael GUTTADAURO
摘要： A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
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公开(公告)号：US20200269063A1
公开(公告)日：2020-08-27
申请号：US16808631
申请日：2020-03-04
发明人： Thomas BOYAJIAN , Mark Carota , Brian Mazejka , Michael Leccese
摘要： An illuminator for photodynamically diagnosing or treating a surface includes a plurality of panels. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of panels. The plurality of light sources are configured to irradiate the surface with substantially uniform intensity visible light. The illuminator also includes a heat source configured to emit heat to a patient. The heat increases the generation of a photoactivatable agent and thus shortens the time needed to complete photodynamic therapy
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公开(公告)号：US20170216616A1
公开(公告)日：2017-08-03
申请号：US15487991
申请日：2017-04-14
发明人： Thomas BOYAJIAN , Mark CAROTA , Brian MAZEJKA
CPC分类号： A61N5/062 , A61B5/0064 , A61B5/0082 , A61B5/01 , A61B2560/0242 , A61N5/0616 , A61N2005/0626 , A61N2005/0633 , A61N2005/0642 , A61N2005/0651 , A61N2005/0652 , A61N2005/0662 , A61N2005/0663
摘要： An illuminator for photodynamically diagnosing or treating a surface includes a plurality of panels. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of panels. The plurality of light sources are configured to irradiate the surface with substantially uniform intensity visible light. The illuminator also includes a heat source configured to emit heat to a patient. The heat increases the generation of a photoactivatable agent and thus shortens the time needed to complete photodynamic therapy
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公开(公告)号：US20160317831A1
公开(公告)日：2016-11-03
申请号：US15207405
申请日：2016-07-11
发明人： SCOTT LUNDAHL
CPC分类号： A61N5/062 , A61K9/0014 , A61K41/0061 , A61N5/0616 , A61N2005/0662
摘要： This application is directed to a method of treating a patient with acne by applying a photodynamic agent to skin having acne lesions, waiting at least 12 hours, and then exposing the skin to which the photodynamic agent has been applied to light that causes an activation reaction.
摘要翻译： 本申请涉及通过将光动力剂施用于具有痤疮损伤的皮肤，等待至少12小时，然后将已经施加光动力学试剂的皮肤暴露于引起活化反应的光的方法来治疗患有痤疮的患者的方法 。
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公开(公告)号：US11697028B2
公开(公告)日：2023-07-11
申请号：US17942353
申请日：2022-09-12
发明人： Thomas Boyajian , Mark Carota , Brian Mazejka
CPC分类号： A61N5/062 , A61B5/0064 , A61B5/0082 , A61N2005/0626 , A61N2005/0633 , A61N2005/0642 , A61N2005/0651 , A61N2005/0652 , A61N2005/0662 , A61N2005/0663
摘要： An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of first panels or the at least one second panel and configured to irradiate the surface with substantially uniform intensity visible light. The plurality of first panels and the at least one second panel are rotatably connected. The at least one second panel is connected on each side to one of the plurality of first panels. The second panel acts as a “lighted hinge” to reduce or eliminate optical dead spaces between adjacent panels when the illuminator is bent into a certain configuration.
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公开(公告)号：US11690914B2
公开(公告)日：2023-07-04
申请号：US17876224
申请日：2022-07-28
发明人： Scott Lundahl , Michael Guttadauro
CPC分类号： A61K41/0061 , A61K9/0014 , A61K9/08 , A61K31/75 , A61K47/10 , A61N5/062 , A61P17/12 , A61N2005/0633 , A61N2005/0642 , A61N2005/0652 , A61N2005/0659 , A61N2005/0663
摘要： A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
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公开(公告)号：US11571478B2
公开(公告)日：2023-02-07
申请号：US17487698
申请日：2021-09-28
发明人： Scott Lundahl , Michael Guttadauro
摘要： A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
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公开(公告)号：US11446512B2
公开(公告)日：2022-09-20
申请号：US16791004
申请日：2020-02-14
发明人： Thomas Boyajian , Mark Carota , Brian Mazejka
摘要： An adjustable illuminator for photodynamically diagnosing or treating a surface includes a plurality of first panels and at least one second panel. The plurality of first panels have wider widths and the at least one second panel has a narrower width. The narrower width is less than the wider widths. The illuminator further includes a plurality of light sources, each mounted to one of the plurality of first panels or the at least one second panel and configured to irradiate the surface with substantially uniform intensity visible light. The plurality of first panels and the at least one second panel are rotatably connected. The at least one second panel is connected on each side to one of the plurality of first panels. The second panel acts as a “lighted hinge” to reduce or eliminate optical dead spaces between adjacent panels when the illuminator is bent into a certain configuration.
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公开(公告)号：US20210001101A1
公开(公告)日：2021-01-07
申请号：US17027872
申请日：2020-09-22
发明人： Thomas BOYAJIAN , Mark CAROTA
摘要： An applicator for dispensing a solution having two or more components includes a hollow body having a head provided at one end of the hollow body for dispersion of the solution and a breaking mechanism attached to the hollow body. The breaking mechanism includes at least one projection extendable into an interior of the hollow body. The applicator further includes a plurality of ampoules placed in the interior of the hollow body. The plurality of ampoules contains the two or more components. Upon activation of the breaking mechanism, the at least one projection applies a force to the plurality of ampoules such that the plurality of ampoules break and release the two or more components to form the solution.
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