公开(公告)号：US20100326777A1

公开(公告)日：2010-12-30

申请号：US12801847

申请日：2010-06-29

申请人： Shoichi Noguchi ,  Daisuke Tanabe ,  Takeshi Fujiki ,  Koichi Masuko ,  Shigeru Hayashi ,  Koji Fukui ,  Yoichi Kumemura ,  Hayuru Inoue ,  Seiko Tsubota

发明人： Shoichi Noguchi ,  Daisuke Tanabe ,  Takeshi Fujiki ,  Koichi Masuko ,  Shigeru Hayashi ,  Koji Fukui ,  Yoichi Kumemura ,  Hayuru Inoue ,  Seiko Tsubota

IPC分类号： F16D55/225

CPC分类号： F16D65/0978 ,  F16D65/0972 ,  F16D66/02

摘要： A disc brake that suppresses braking noises when a vehicle moves backward include an urging spring urging a friction pad toward a rotationally exiting side of a disc when the vehicle moves forward, the urging spring being arranged between a hook portion of the friction pad and a torque receiving portion of a carrier. The urging spring formed through bend of an elastic plate material has its spring constant that is set to be a small value to avoid resonance frequency causing noise where the base end side thereof is fixed to the hook portion of the backing plate while the top end side thereof elastically abuts to the torque receiving portion of the carrier. The urging spring is located at the position that is outside in the radial direction from the center position of the hook portion in its width direction.

摘要翻译： 当车辆向后移动时抑制制动噪声的盘式制动器包括当车辆向前移动时将摩擦垫推向盘的旋转离开侧的推动弹簧，所述推动弹簧布置在摩擦垫的钩部与扭矩之间 接收部分。 通过弹性板材的弯曲而形成的施力弹簧的弹簧常数被设定为小的值，以避免其基端侧固定在背板的钩部上的共振频率引起的噪声，而顶端侧 其弹性地抵靠载体的扭矩接收部分。 推动弹簧位于从钩部的宽度方向的中心位置向径向外侧的位置。

公开(公告)号：US07381760B2

公开(公告)日：2008-06-03

申请号：US10878254

申请日：2004-06-29

申请人： Seiji Aida ,  Shinya Fujimatsu ,  Kaori Nakano ,  Shinichi Sato ,  Daisuke Tanabe

发明人： Seiji Aida ,  Shinya Fujimatsu ,  Kaori Nakano ,  Shinichi Sato ,  Daisuke Tanabe

IPC分类号： C08J3/00 ,  C08K3/20 ,  C08L39/00 ,  C08L67/00 ,  C09D11/00

CPC分类号： C09D11/322 ,  C09B67/0034 ,  C09B67/0035 ,  C09B67/0063 ,  C09B67/0085 ,  C09B68/4257 ,  C09B68/441 ,  C09B68/446 ,  C09D11/101

摘要： The invention relates to a pigment dispersion comprising: a condensate of or a salt between a polyallylamine and a polyester having a free carboxylic acid or the salt; a pigment derivative represented by the following general formula (1); a pigment; and an organic solvent, (P−X)−[N(R1, R2, R3, R4)]+  general formula (1) wherein p represents an organic dyestuff residue; X represents a sulfonic acid group or a carboxylic acid group; R1 represents an alkyl group having 5 to 20 carbon atoms; and R2, R3 and R4 each independently represents a hydrogen atom or an alkyl group having 1 to 20 carbon atoms.

摘要翻译： 本发明涉及一种颜料分散体，其包含：聚烯丙胺与具有游离羧酸或其盐的聚酯之间的盐或其盐的缩合物; 由以下通式（1）表示的颜料衍生物; 颜料; 和有机溶剂<？in-line-formula description =“In-line Formulas”end =“lead”？>（PX）[N（R 1） ，R 2 R 3，R 3，R 4）] - 通式（1）＆lt;＆Sigma;＆CenterDot;＆CenterDot;＆CenterDot; -formulae description =“In-line Formulas”end =“tail”？>其中p表示有机染料残留物; X表示磺酸基或羧酸基; R 1表示碳原子数5〜20的烷基， R 2，R 3和R 4各自独立地表示氢原子或碳原子数1〜20的烷基。

公开(公告)号：US09360068B2

公开(公告)日：2016-06-07

申请号：US12801847

申请日：2010-06-29

申请人： Shoichi Noguchi ,  Daisuke Tanabe ,  Takeshi Fujiki ,  Koichi Masuko ,  Shigeru Hayashi ,  Koji Fukui ,  Yoichi Kumemura ,  Hayuru Inoue ,  Seiko Tsubota

发明人： Shoichi Noguchi ,  Daisuke Tanabe ,  Takeshi Fujiki ,  Koichi Masuko ,  Shigeru Hayashi ,  Koji Fukui ,  Yoichi Kumemura ,  Hayuru Inoue ,  Seiko Tsubota

IPC分类号： F16D65/40 ,  F16D65/097 ,  F16D66/02

CPC分类号： F16D65/0978 ,  F16D65/0972 ,  F16D66/02

摘要： A disc brake that suppresses braking noises when a vehicle moves backward include an urging spring urging a friction pad toward a rotationally exiting side of a disc when the vehicle moves forward, the urging spring being arranged between a hook portion of the friction pad and a torque receiving portion of a carrier. The urging spring formed through bend of an elastic plate material has its spring constant that is set to be a small value to avoid resonance frequency causing noise where the base end side thereof is fixed to the hook portion of the backing plate while the top end side thereof elastically abuts to the torque receiving portion of the carrier. The urging spring is located at the position that is outside in the radial direction from the center position of the hook portion in its width direction.

摘要翻译： 当车辆向后移动时抑制制动噪声的盘式制动器包括当车辆向前移动时将摩擦垫推向盘的旋转离开侧的推动弹簧，所述推动弹簧布置在摩擦垫的钩部与扭矩之间 接收部分。 通过弹性板材的弯曲而形成的施力弹簧的弹簧常数被设定为小的值，以避免其基端侧固定在背板的钩部上的共振频率引起的噪声，而顶端侧 其弹性地抵靠载体的扭矩接收部分。 推动弹簧位于从钩部的宽度方向的中心位置向径向外侧的位置。

公开(公告)号：US07928264B2

公开(公告)日：2011-04-19

申请号：US11547847

申请日：2005-09-20

申请人： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

发明人： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

IPC分类号： C07C213/00

CPC分类号： C07D213/70 ,  C07C311/51 ,  C07C323/63 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/10 ,  C07D209/42 ,  C07D213/38 ,  Y02P20/55

摘要： The present invention relates to a compound of the formula [I]: wherein (a), in which —Y—, R4, R5 and R6 are4 R5 each as defined in the description, etc., R1 is hydrogen, halogen, lower alkyl, hydroxy, etc., R2 is hydrogen, lower alkyl or hydroxy(lower)alkyl, R3 is hydrogen or an amino protective group, 20R7 is hydrogen, lower alkyl, cyclo(lower)alkyl, lower R9 alkenyl, —Z—R9 or (b), in which —Z— is —0—, —S—, R9 —SO— or —SO2—, and each R9 is independently hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R8 is -D-E-R10, in which -D- is —CONHSO2— or —S02NHCO—, E is bond or lower alkylene, and R10 is halogen, cyano, carboxy, etc., or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of ulcer, overactive bladder, and the like.

摘要翻译： 本发明涉及式[I]的化合物：其中（a）其中-Y-，R4，R5和R6各自如说明书中所定义的R 5等，R 1是氢，卤素，低级烷基 ，羟基等，R2是氢，低级烷基或羟基（低级）烷基，R3是氢或氨基保护基，20R7是氢，低级烷基，环（低级）烷基，低级R9链烯基，-Z-R9或 （b）中，-Z-是-O - ， - S - ，R 9 -SO-或-SO 2 - ，各R 9独立地是氢，低级烷基，环（低级）烷基等， DE-R10，其中-D-是-CONHSO2-或-SO 2 NHCO-，E是键或低级亚烷基，R 10是卤素，氰基，羧基等，或其前药或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于溃疡，膀胱过度活动症等的预防和/或治疗性治疗。

公开(公告)号：US07077899B2

公开(公告)日：2006-07-18

申请号：US10756350

申请日：2004-01-14

申请人： Takashi Kamikubo ,  Daisuke Tanabe ,  Tetsuya Sai

发明人： Takashi Kamikubo ,  Daisuke Tanabe ,  Tetsuya Sai

IPC分类号： C09D11/02 ,  C09D11/10 ,  C08K5/3492

CPC分类号： C09D11/326 ,  C09D11/03

摘要： A pigment dispersing agent of the formula (1) capable of providing a printing ink or a coating composition excellent in fluidity and dispersion stability and a dry coating excellent in gloss, a pigment composition containing the same and a pigment dispersion containing the same, wherein X1 is —NH—, —O—, —CONH—, —SO2NH—, —CH2NH—, —CH2NHCOCH2NH— or —X3—Y—X4—, X2 and X4 are —NH— or —O—, X3 is —CONH—, —SO2NH—, —CH2NH—, —NHCO— or —NHSO2—, Y is an alkylene group, an alkenylene group or an arylene group, Z is —SO3M or —COOM, R1 is a heterocyclic ring residue or an aromatic ring residue, Q is —O—R2, —NH—R2, a halogen group, —X1—R1 or —X2—Y-Z, R2 is a hydrogen atom, an alkyl group or an alkenyl group, and M is one equivalent of a monovalent to trivalent cation.

摘要翻译： 一种能够提供流动性和分散稳定性优异的印刷油墨或涂料组合物的光泽性优异的颜料分散剂，含有它们的颜料组合物和含有它们的颜料分散体，其中X N 1是-NH-， - O - ， - CONH - ， - SO 2 NH-，-CH 2 NH-， - CH- 2→2 NHCOCH 2 NH-或-X 3 -YX 4 - ，X 2 - 和X 4是-NH-或-O-，X 3是-CONH - ， - SO 2 NH-， - CH＆lt; SUB > 2个NH-，-NHCO-或-NHSO 2 - ，Y是亚烷基，亚烯基或亚芳基，Z是-SO 3 卤素基团，-X 1 -R 1或-X 2 -YZ，R 2是 氢原子，烷基或烯基，M为一价至三价阳离子的1当量。

公开(公告)号：US20050137236A1

公开(公告)日：2005-06-23

申请号：US11016886

申请日：2004-12-21

申请人： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

发明人： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

IPC分类号： C07C229/38 ,  C07C229/56 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  C07D213/38 ,  C07D213/61 ,  A61K31/44 ,  A61K31/195

CPC分类号： C07C229/56 ,  C07C229/38 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  Y02P20/55

摘要： The present invention relates to a compound formula[I]: wherein X is bond, —CH2—, —O— or —NH—, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen or an amino protective group, R4, R5 and R6 are each independently hydrogen or optionally substituted lower alkyl, R7 is -Z-R13, in which Z is bond, etc., and R13 is carboxy, lower alkoxycarbonyl, (lower alkylsulfonyl)carbamoyl or lower alkanoylsulfamoyl, R8 is —Y—R9, in which Y is bond, —CH2—, —O—, —S—, etc., and R9 is hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R11 is hydrogen, lower alkyl, lower alkoxy, etc., or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

摘要翻译： 本发明涉及化合物式[I]：其中X是键，-CH 2 - ， - O-或-NH-，R 1和R 2 > 12个各自独立地为氢，卤素，低级烷基等，R 2为氢或任选取代的低级烷基，R 3为氢或氨基 保护基，R 4，R 5和R 6各自独立地为氢或任选取代的低级烷基，R 7 O 其中Z为键，等等，R 13为羧基，低级烷氧基羰基，（低级烷基磺酰基）氨基甲酰基或低级烷酰基氨磺酰基，R 0为 其中Y为键，-CH 2 - ， - O - ， - S-等，其中R为 - 低级烷基，环（低级）烷基等，R 11是氢，低级烷基，低级烷氧基等，或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于预防和/或治疗呼吸窘迫症或尿失禁。

公开(公告)号：US07417060B2

公开(公告)日：2008-08-26

申请号：US11016886

申请日：2004-12-21

申请人： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

发明人： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

IPC分类号： A61K31/44 ,  A61K31/195

CPC分类号： C07C229/56 ,  C07C229/38 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  Y02P20/55

摘要： The present invention relates to a compound formula[I]: wherein X is bond, —CH2—, —O— or —NH—, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen or an amino protective group, R4, R5 and R6 are each independently hydrogen or optionally substituted lower alkyl, R7 is -Z-R13, in which Z is bond, etc., and R13 is carboxy, lower alkoxycarbonyl, (lower alkylsulfonyl)carbamoyl or lower alkanoylsulfamoyl, R8 is —Y—R9, in which Y is bond, —CH2—, —O—, —S—, etc., and R9 is hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R11 is hydrogen, lower alkyl, lower alkoxy, etc., or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

摘要翻译： 本发明涉及化合物式[I]：其中X是键，-CH 2 - ， - O-或-NH-，R 1和R 2 > 12个各自独立地为氢，卤素，低级烷基等，R 2为氢或任选取代的低级烷基，R 3为氢或氨基 保护基，R 4，R 5和R 6各自独立地为氢或任选取代的低级烷基，R 7 O 其中Z为键，等等，R 13为羧基，低级烷氧基羰基，（低级烷基磺酰基）氨基甲酰基或低级烷酰基氨磺酰基，R 0为 其中Y为键，-CH 2 - ， - O - ， - S-等，其中R为 - 低级烷基，环（低级）烷基等，R 11是氢，低级烷基，低级烷氧基等，或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于预防和/或治疗呼吸窘迫症或尿失禁。

公开(公告)号：US20080039506A1

公开(公告)日：2008-02-14

申请号：US11547847

申请日：2005-09-20

申请人： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

发明人： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

IPC分类号： A61K31/44 ,  A61K31/164 ,  A61K31/265 ,  A61P1/04 ,  C07C233/00 ,  C07D213/02 ,  C07C271/00 ,  A61P13/10 ,  A61K31/35 ,  A61K31/404

CPC分类号： C07D213/70 ,  C07C311/51 ,  C07C323/63 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/10 ,  C07D209/42 ,  C07D213/38 ,  Y02P20/55

摘要： The present invention relates to a compound of the formula [I]: wherein (a), in which —Y—, R4, R5 and R6 are4 R5 each as defined in the description, etc., R1 is hydrogen, halogen, lower alkyl, hydroxy, etc., R2 is hydrogen, lower alkyl or hydroxy(lower)alkyl, R3 is hydrogen or an amino protective group, 20R7 is hydrogen, lower alkyl, cyclo(lower)alkyl, lower R9 alkenyl, -Z-R9 or (b), in which -Z- is -0-, —S—, R9—SO— or —SO2—, and each R9 is independently hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R8 is -D-E-R , in which -D- is —CONHSO2— or —S02NHCO—, E is bond or lower alkylene, and R10 is halogen, cyano, carboxy, etc., or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of ulcer, overactive bladder, and the like.

摘要翻译： 本发明涉及式[I]化合物：其中（a），其中-Y-，R 4，R 5和R 6 每一个如说明书中所定义的，其中R 1是氢，卤素，低级烷基，羟基 等等，R 2是氢，低级烷基或羟基（低级）烷基，R 3是氢或氨基保护基，R 20，R 20， 其中-Z-是-O - ， - S - ， - S（O） - ， - （R） 9个-SO-或-SO 2 - ，每个R 9独立地是氢，低级烷基，环（低级）烷基等，R 其中D是-CONHSO 2 - 或-SO 2 NHCO-，其中D是 - E是键或低级亚烷基，R 10是卤素，氰基，羧基等，或其前药或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于溃疡，膀胱过度活动症等的预防和/或治疗性治疗。