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    Device for controlling operation of injection molder
    1.
    发明授权
    Device for controlling operation of injection molder 失效
    控制注塑机操作的装置

    公开(公告)号：US4833616A

    公开(公告)日：1989-05-23

    申请号：US927381

    申请日：1986-11-06

    Applicant: Kazuo Takei ,  Susumu Toda ,  Yutaka Nakaya ,  Akimitsu Mita

    Inventor： Kazuo Takei ,  Susumu Toda ,  Yutaka Nakaya ,  Akimitsu Mita

    IPC: B22D17/32 ,  B22D17/26 ,  B29C45/03 ,  B29C45/40 ,  B29C45/64 ,  B29C45/76 ,  B29C45/84

    CPC classification number: B29C45/7626

    Abstract: A device for controlling the operation of an injection molder is disclosed. A fall detection signal is produced when a product falls from the mold. If the full detection signal is generated before the lapse of a fixed time preset in a timer from the instant of appearance of a mold-opening signal from a mold-opening signal generator, the next molding cycle is started. If no fall detection signal is generated within the preset time of the timer, an alarm is generated.

    Abstract translation: 公开了一种用于控制注塑机的操作的装置。 当产品从模具落下时产生跌落检测信号。 如果在从打开开模信号发生器的开模信号出现之后的定时器中预定的固定时间经过之前产生完整检测信号，则开始下一个成型周期。 如果在定时器的预设时间内没有产生下降检测信号，则产生报警。

    Aminoalcohol derivatives
    3.
    发明申请
    Aminoalcohol derivatives 失效
    氨基醇衍生物

    公开(公告)号：US20050137236A1

    公开(公告)日：2005-06-23

    申请号：US11016886

    申请日：2004-12-21

    Applicant: Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

    Inventor： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

    IPC: C07C229/38 ,  C07C229/56 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  C07D213/38 ,  C07D213/61 ,  A61K31/44 ,  A61K31/195

    CPC classification number: C07C229/56 ,  C07C229/38 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  Y02P20/55

    Abstract: The present invention relates to a compound formula[I]: wherein X is bond, —CH2—, —O— or —NH—, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen or an amino protective group, R4, R5 and R6 are each independently hydrogen or optionally substituted lower alkyl, R7 is -Z-R13, in which Z is bond, etc., and R13 is carboxy, lower alkoxycarbonyl, (lower alkylsulfonyl)carbamoyl or lower alkanoylsulfamoyl, R8 is —Y—R9, in which Y is bond, —CH2—, —O—, —S—, etc., and R9 is hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R11 is hydrogen, lower alkyl, lower alkoxy, etc., or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

    Abstract translation: 本发明涉及化合物式[I]：其中X是键，-CH 2 - ， - O-或-NH-，R 1和R 2 > 12个各自独立地为氢，卤素，低级烷基等，R 2为氢或任选取代的低级烷基，R 3为氢或氨基 保护基，R 4，R 5和R 6各自独立地为氢或任选取代的低级烷基，R 7 O 其中Z为键，等等，R 13为羧基，低级烷氧基羰基，（低级烷基磺酰基）氨基甲酰基或低级烷酰基氨磺酰基，R 0为 其中Y为键，-CH 2 - ， - O - ， - S-等，其中R为 - 低级烷基，环（低级）烷基等，R 11是氢，低级烷基，低级烷氧基等，或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于预防和/或治疗呼吸窘迫症或尿失禁。

    Aminoalcohol derivatives
    4.
    发明授权
    Aminoalcohol derivatives 失效
    氨基醇衍生物

    公开(公告)号：US07928264B2

    公开(公告)日：2011-04-19

    申请号：US11547847

    申请日：2005-09-20

    Applicant: Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

    Inventor： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

    IPC: C07C213/00

    CPC classification number: C07D213/70 ,  C07C311/51 ,  C07C323/63 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/10 ,  C07D209/42 ,  C07D213/38 ,  Y02P20/55

    Abstract: The present invention relates to a compound of the formula [I]: wherein (a), in which —Y—, R4, R5 and R6 are4 R5 each as defined in the description, etc., R1 is hydrogen, halogen, lower alkyl, hydroxy, etc., R2 is hydrogen, lower alkyl or hydroxy(lower)alkyl, R3 is hydrogen or an amino protective group, 20R7 is hydrogen, lower alkyl, cyclo(lower)alkyl, lower R9 alkenyl, —Z—R9 or (b), in which —Z— is —0—, —S—, R9 —SO— or —SO2—, and each R9 is independently hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R8 is -D-E-R10, in which -D- is —CONHSO2— or —S02NHCO—, E is bond or lower alkylene, and R10 is halogen, cyano, carboxy, etc., or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of ulcer, overactive bladder, and the like.

    Abstract translation: 本发明涉及式[I]的化合物：其中（a）其中-Y-，R4，R5和R6各自如说明书中所定义的R 5等，R 1是氢，卤素，低级烷基 ，羟基等，R2是氢，低级烷基或羟基（低级）烷基，R3是氢或氨基保护基，20R7是氢，低级烷基，环（低级）烷基，低级R9链烯基，-Z-R9或 （b）中，-Z-是-O - ， - S - ，R 9 -SO-或-SO 2 - ，各R 9独立地是氢，低级烷基，环（低级）烷基等， DE-R10，其中-D-是-CONHSO2-或-SO 2 NHCO-，E是键或低级亚烷基，R 10是卤素，氰基，羧基等，或其前药或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于溃疡，膀胱过度活动症等的预防和/或治疗性治疗。

    Aminoalcohol derivatives
    6.
    发明授权
    Aminoalcohol derivatives 失效
    氨基醇衍生物

    公开(公告)号：US07417060B2

    公开(公告)日：2008-08-26

    申请号：US11016886

    申请日：2004-12-21

    Applicant: Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

    Inventor： Kouji Hattori ,  Susumu Toda ,  Masashi Imanishi ,  Shinji Ito ,  Kenichi Washizuka ,  Takanobu Araki ,  Minoru Sakurai ,  Daisuke Tanabe

    IPC: A61K31/44 ,  A61K31/195

    CPC classification number: C07C229/56 ,  C07C229/38 ,  C07C271/16 ,  C07C311/51 ,  C07C323/63 ,  Y02P20/55

    Abstract: The present invention relates to a compound formula[I]: wherein X is bond, —CH2—, —O— or —NH—, R1 and R12 are each independently hydrogen, halogen, lower alkyl, etc., R2 is hydrogen or optionally substituted lower alkyl, R3 is hydrogen or an amino protective group, R4, R5 and R6 are each independently hydrogen or optionally substituted lower alkyl, R7 is -Z-R13, in which Z is bond, etc., and R13 is carboxy, lower alkoxycarbonyl, (lower alkylsulfonyl)carbamoyl or lower alkanoylsulfamoyl, R8 is —Y—R9, in which Y is bond, —CH2—, —O—, —S—, etc., and R9 is hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R11 is hydrogen, lower alkyl, lower alkoxy, etc., or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of pollakiurea or urinary incontinence.

    Abstract translation: 本发明涉及化合物式[I]：其中X是键，-CH 2 - ， - O-或-NH-，R 1和R 2 > 12个各自独立地为氢，卤素，低级烷基等，R 2为氢或任选取代的低级烷基，R 3为氢或氨基 保护基，R 4，R 5和R 6各自独立地为氢或任选取代的低级烷基，R 7 O 其中Z为键，等等，R 13为羧基，低级烷氧基羰基，（低级烷基磺酰基）氨基甲酰基或低级烷酰基氨磺酰基，R 0为 其中Y为键，-CH 2 - ， - O - ， - S-等，其中R为 - 低级烷基，环（低级）烷基等，R 11是氢，低级烷基，低级烷氧基等，或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于预防和/或治疗呼吸窘迫症或尿失禁。

    Aminoalcohol Derivatives
    7.
    发明申请
    Aminoalcohol Derivatives 失效
    氨基醇衍生物

    公开(公告)号：US20080039506A1

    公开(公告)日：2008-02-14

    申请号：US11547847

    申请日：2005-09-20

    Applicant: Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

    Inventor： Kouji Hattori ,  Susumu Toda ,  Kenichi Washizuka ,  Shinji Ito ,  Daisuke Tanabe ,  Takanobu Araki ,  Minoru Sakurai

    IPC: A61K31/44 ,  A61K31/164 ,  A61K31/265 ,  A61P1/04 ,  C07C233/00 ,  C07D213/02 ,  C07C271/00 ,  A61P13/10 ,  A61K31/35 ,  A61K31/404

    CPC classification number: C07D213/70 ,  C07C311/51 ,  C07C323/63 ,  C07C2601/08 ,  C07C2601/14 ,  C07C2602/10 ,  C07D209/42 ,  C07D213/38 ,  Y02P20/55

    Abstract: The present invention relates to a compound of the formula [I]: wherein (a), in which —Y—, R4, R5 and R6 are4 R5 each as defined in the description, etc., R1 is hydrogen, halogen, lower alkyl, hydroxy, etc., R2 is hydrogen, lower alkyl or hydroxy(lower)alkyl, R3 is hydrogen or an amino protective group, 20R7 is hydrogen, lower alkyl, cyclo(lower)alkyl, lower R9 alkenyl, -Z-R9 or (b), in which -Z- is -0-, —S—, R9—SO— or —SO2—, and each R9 is independently hydrogen, lower alkyl, cyclo(lower)alkyl, etc., and R8 is -D-E-R , in which -D- is —CONHSO2— or —S02NHCO—, E is bond or lower alkylene, and R10 is halogen, cyano, carboxy, etc., or a prodrug thereof or a salt thereof. The compound [I] of the present invention and pharmaceutically acceptable salts thereof are useful for the prophylactic and/or the therapeutic treatment of ulcer, overactive bladder, and the like.

    Abstract translation: 本发明涉及式[I]化合物：其中（a），其中-Y-，R 4，R 5和R 6 每一个如说明书中所定义的，其中R 1是氢，卤素，低级烷基，羟基 等等，R 2是氢，低级烷基或羟基（低级）烷基，R 3是氢或氨基保护基，R 20，R 20， 其中-Z-是-O - ， - S - ， - S（O） - ， - （R） 9个-SO-或-SO 2 - ，每个R 9独立地是氢，低级烷基，环（低级）烷基等，R 其中D是-CONHSO 2 - 或-SO 2 NHCO-，其中D是 - E是键或低级亚烷基，R 10是卤素，氰基，羧基等，或其前药或其盐。 本发明的化合物[I]及其药学上可接受的盐可用于溃疡，膀胱过度活动症等的预防和/或治疗性治疗。

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