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48 条记录 (耗时 0.025 秒)

    Formulations and process for extending the vase life of cut flowers
    7.
    发明授权
    Formulations and process for extending the vase life of cut flowers 失效
    延长切花花瓶寿命的配方和工艺

    公开(公告)号：US5284818A

    公开(公告)日：1994-02-08

    申请号：US26920

    申请日：1993-03-08

    申请人： Warren E. Shafer ,  Derek D. Woolard ,  Neyyan K. P. Samuel ,  Gregory D. Venburg ,  Balan N. Devisetty ,  Daniel F. Heiman

    发明人： Warren E. Shafer ,  Derek D. Woolard ,  Neyyan K. P. Samuel ,  Gregory D. Venburg ,  Balan N. Devisetty ,  Daniel F. Heiman

    IPC分类号： A01N3/02

    CPC分类号： A01N3/02

    摘要： Stable, solid cut flower preservatives having excellent shelf life and stability comprise from about 1 part by weight to about 99 parts by weight of a sugar, glycoside or mixture thereof, from about 0.05 part by weight to about 2 part by weight of an ACC synthase inhibitor selected from L-trans-2-amino-4-(2-aminoethoxy)-3-butenoic acid and carboxymethoxylamine, from about 0.5 part by weight to about 8 parts by weight of aluminum sulfate having less than about 27 percent by weight water of hydration, and from about 0.05 part by weight to about 5 parts by weight of an antimicrobial agent.

    摘要翻译： 具有优异保质期和稳定性的稳定的固体切花防腐剂包含约1重量份至约99重量份的糖，糖苷或其混合物，约0.05重量份至约2重量份的ACC合酶 选自L-反式-2-氨基-4-（2-氨基乙氧基）-3-丁烯酸和羧基甲氧基胺的抑制剂，约0.5重量份至约8重量份的具有小于约27重量％水的硫酸铝 的水合，以及约0.05重量份至约5重量份的抗微生物剂。

    Method and reagents for detecting amphetamine and/or D-methamphetamine in biological samples
    8.
    发明授权
    Method and reagents for detecting amphetamine and/or D-methamphetamine in biological samples 失效
    用于检测生物样品中苯丙胺和/或D-甲基苯丙胺的方法和试剂

    公开(公告)号：US5262333A

    公开(公告)日：1993-11-16

    申请号：US898238

    申请日：1992-06-12

    申请人： Daniel F. Heiman ,  Sharon A. Johnson ,  Hsiang-Yun Y. Hu

    发明人： Daniel F. Heiman ,  Sharon A. Johnson ,  Hsiang-Yun Y. Hu

    IPC分类号： G01N33/542 ,  G01N33/94

    CPC分类号： G01N33/946 ,  G01N33/542 ,  Y10S436/816

    摘要： This disclosure relates to a method and reagents for determining amphetamine and d-methamphetamine in a biological fluid, such as urine. In particular, this disclosure relates to improvements in a fluorescence polarization immunoassay procedure for determining the presence of amphetamine and d-methamphetamine in a single assay and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described includes pretreatment of the biological sample to eliminate cross reactants such as .beta.-hydroxyphenethylamine by preincubating the sample solely with an aqueous periodate solution having a pH from about 4.0 to about 7.5 without adjustment to an alkaline pH, and contacting the sample with riboflavin binding protein to reduce interference from fluorescent components in the sample. The procedure also maintains the cross reactivity of the immunoassay for tyramine at about 0.4% and for 1-methamphetamine below about 5.1% and eliminates the necessity of using controlled substances as starting materials.

    摘要翻译： 本公开涉及用于在生物流体例如尿中测定苯丙胺和d-甲基苯丙胺的方法和试剂。 特别地，本公开涉及在单次测定中用于确定苯丙胺和d-甲基苯丙胺的存在的荧光偏振免疫测定方法的改进，以及在这种方法中用作试剂的新型示踪剂化合物。 所述方法包括通过预先处理生物样品以消除交叉反应物例如β-羟基苯乙胺，通过仅用pH约4.0至约7.5的高碘酸钠溶液预温育样品，而不调节至碱性pH，并将样品与核黄素接触 结合蛋白以减少样品中荧光成分的干扰。 该方法还保持酪胺的免疫测定在约0.4％的交叉反应性和低于约5.1％的1-甲基苯丙胺，并且不需要使用受控物质作为起始原料。

    Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
    9.
    发明授权
    Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies 失效
    鸦片生物碱及其代谢物的免疫测定; 示踪剂，免疫原和抗体

    公开(公告)号：US4939264A

    公开(公告)日：1990-07-03

    申请号：US885054

    申请日：1986-07-14

    申请人： Daniel F. Heiman ,  Daniel S. Raden ,  Robert E. Dubler

    发明人： Daniel F. Heiman ,  Daniel S. Raden ,  Robert E. Dubler

    IPC分类号： G01N33/53 ,  C07D489/00 ,  C07D489/02 ,  C07D489/08 ,  C07D493/10 ,  C07D519/00 ,  G01N33/94

    CPC分类号： G01N33/9486 ,  C07D489/00 ,  C07D489/02 ,  C07D489/08 ,  Y10S436/80 ,  Y10S436/805 ,  Y10S436/825 ,  Y10S436/826 ,  Y10S530/807

    摘要： The present invention is directed to a fluorescence polarization assay for opiate alkaloids and their metabolites, to the various components needed for preparing and carrying out such an assay and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for making them. The tracers and the immunogens are made from substituted opiate alkaloids. A fluorescein moiety is included in the tracers, while a poly(amino acid) forms a part of the immunogens. The assay is conducted by measuring the degree of polarization retention of the fluorescence resulting when a sample mixed with antiserum and tracer is irradiated with plane-polarized light.

    摘要翻译： 本发明涉及鸦片类生物碱及其代谢产物的荧光偏振测定，制备和进行这种测定所需的各种组分以及制备这些组分的方法。 具体地，公开了示踪剂，免疫原和抗体，以及制备它们的方法。 示踪剂和免疫原由取代的阿片碱生物碱制成。 示踪剂中包含荧光素部分，而聚（氨基酸）形成免疫原的一部分。 通过测量当用平面偏振光照射与抗血清和示踪剂混合的样品时产生的荧光的偏振保持程度来进行测定。