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1.发明授权System and method for acquiring images at maximum acquisition rate while asynchronously sequencing microscope devices 有权用于以显微镜装置异步测序以最大采集速率获取图像的系统和方法公开(公告)号：US06724419B1
公开(公告)日：2004-04-20
申请号：US09638548
申请日：2000-08-14
IPC分类号： H04N718
CPC分类号： G02B21/367 , G01N21/64
摘要： The invention provides an automated microscope system, a computer program product in a computer readable medium and a method for acquiring images at substantially the maximum acquisition rate of a camera while and as devices external to the camera, which vary various parameters of the acquired images, operate asynchronously with the camera so as to allow the acquired images to be displayed as a sequence that shows continuous variation in the acquisition parameters.
摘要翻译： 本发明提供了一种自动显微镜系统，计算机可读介质中的计算机程序产品和用于以相机的大部分最大获取速率获取图像的方法，以及作为改变所获取图像的各种参数的照相机外部的装置， 与相机异步地操作，以便允许所获取的图像被显示为显示采集参数的连续变化的序列。
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公开(公告)号：US06355633B1
公开(公告)日：2002-03-12
申请号：US09535492
申请日：2000-03-24
申请人： Jay E. Wrobel , John F. Rogers , Daniel M. Green , Wenling Kao , James W. Jetter
发明人： Jay E. Wrobel , John F. Rogers , Daniel M. Green , Wenling Kao , James W. Jetter
IPC分类号： A61K31167
CPC分类号： C07C309/51 , C07C309/76 , C07C311/29 , C07C317/44 , C07C317/48 , C07D295/13 , C07D295/26
摘要： This invention provides compounds of formula I having the structure wherein R1, Ar, Ar′, and Q are as defined in the specification, or a pharmaceutically acceptable salt thereof, which are useful as contraceptive agents.
摘要翻译： 本发明提供具有结构的式I化合物，其中R 1，Ar，Ar'和Q如本说明书中所定义，或其药学上可接受的盐，其可用作避孕药。
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3.发明授权Sulfonic acid sulfonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds 失效磺酸磺酰氨基正（（杂芳烷基） - 杂环基酰胺化合物公开(公告)号：US06281227B1
公开(公告)日：2001-08-28
申请号：US09453307
申请日：1999-12-02
申请人： Yong Mi Choi-Sledeski , Heinz W. Pauls , Jeffrey N. Barton , William R. Ewing , Daniel M. Green , Michael R. Becker , Yong Gong , Julian Levell
发明人： Yong Mi Choi-Sledeski , Heinz W. Pauls , Jeffrey N. Barton , William R. Ewing , Daniel M. Green , Michael R. Becker , Yong Gong , Julian Levell
IPC分类号： A61K3147
CPC分类号： A61K45/06 , A61K31/00 , A61K31/4184 , A61K31/4365 , A61K31/437 , A61K31/4709 , A61K31/4725 , A61K31/517 , A61K31/519 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/14 , C07D409/14 , C07D471/04 , C07D491/04 , C07D495/04
摘要： The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, for treating a patient suffering from, or subject to, a physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.
摘要翻译： 本文所述的式I化合物表现出有用的药理活性，因此并入药物组合物中并用于治疗患有某些医学病症的患者。 更具体地说，它们是因子Xa活性的抑制剂。 本发明涉及式I化合物，其含有式I化合物的组合物及其用途，用于治疗患有或经受生理状况的患者，所述生理条件可以通过施用抑制剂的活性而被改善 因子Xa
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4.发明授权Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor 失效促性腺激素释放激素受体的苯并恶唑和苯并噻唑拮抗剂公开(公告)号：US07531542B2
公开(公告)日：2009-05-12
申请号：US11431266
申请日：2006-05-09
IPC分类号： A61K31/497 , C07D413/00 , C07D417/00 , C07D419/00
CPC分类号： C07D417/12 , C07D413/12
摘要： The present invention relates to Gonadotropin Releasing Hormone (GnRH, also known as Luteinizing Hormone Releasing Hormone) receptor antagonists.
摘要翻译： 本发明涉及促性腺激素释放激素（GnRH，也称为促黄体激素释放激素）受体拮抗剂。
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5.发明授权Sulfonic acid or sulfonylamino N-(heteroaralkyl)-azaheterocyclylamide compounds 失效磺酸或磺酰氨基N-（杂芳烷基） - 杂环基酰胺化合物公开(公告)号：US06602864B1
公开(公告)日：2003-08-05
申请号：US09090492
申请日：1998-06-03
申请人： Yong Mi Choi-Sledeski , Henry W. Pauls , Jeffrey N. Barton , William R. Ewing , Daniel M. Green , Michael R. Becker , Yong Gong
发明人： Yong Mi Choi-Sledeski , Henry W. Pauls , Jeffrey N. Barton , William R. Ewing , Daniel M. Green , Michael R. Becker , Yong Gong
IPC分类号： A61K3155
CPC分类号： C07D409/14 , A61K31/00 , A61K31/4184 , A61K31/4365 , A61K31/437 , A61K31/4709 , A61K31/4725 , A61K31/517 , A61K31/519 , A61K45/06 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/06 , C07D403/14 , C07D471/04 , C07D491/04 , C07D495/04
摘要： The compounds of formula I herein exhibit useful pharmacological activity and accordingly are incorporated into pharmaceutical compositions and used in the treatment of patients suffering from certain medical disorders. More specifically, they are inhibitors of the activity of Factor Xa. The present invention is directed to compounds of formula I, compositions containing compounds of formula I, and their use, which are for treating a patient suffering from, or subject to, physiological condition which can be ameliorated by the administration of an inhibitor of the activity of Factor Xa.
摘要翻译： 本文所述的式I化合物表现出有用的药理活性，因此并入药物组合物中并用于治疗患有某些医学病症的患者。 更具体地说，它们是因子Xa活性的抑制剂。 本发明涉及式I化合物，其含有式I化合物的组合物及其用途，其用于治疗患有或经受生理条件的患者，其可通过施用活性抑制剂而改善 因子Xa。
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