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1.发明授权公开(公告)号：US08476285B2
公开(公告)日：2013-07-02
申请号：US12494917
申请日：2009-06-30
Applicant: Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
Inventor： Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
IPC: A61K31/52 , C07D473/34 , A61P35/00
CPC classification number: A61K31/52 , A61K31/522 , C07D473/34
Abstract: The invention relates to compounds of Formulae I-III: and therapeutic uses thereof, wherein A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carbocyclic group; B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group; R1 is chosen from hydro, alkyl, aryl, heteroaryl, amino, or halo; and L1, L2, are as defined herein.
Abstract translation: 本发明涉及式I-III的化合物及其治疗用途，其中A选自取代或未取代的芳基，杂芳基，杂环或碳环基团; B选自取代或未取代的哌啶，高哌啶，哌嗪，吡咯烷或氮杂环丁烷基; R 1选自氢，烷基，芳基，杂芳基，氨基或卤素; 和L1，L2如本文所定义。
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Patent Agency Ranking
公开(公告)号：US20070213271A1
公开(公告)日：2007-09-13
申请号：US11626687
申请日：2007-01-24
Applicant: Kenton Zavitz , Daniel Wettstein , Scott Morham , Adrian Hobden
Inventor： Kenton Zavitz , Daniel Wettstein , Scott Morham , Adrian Hobden
CPC classification number: C07K14/005 , A61K38/00 , A61K47/42 , A61K47/64 , A61K48/00 , C07K2319/00 , C12N2740/16222 , C12N2740/16322
Abstract: Methods for inhibiting HIV propagation and treating HIV infection are provided which include administering to cells infected with HIV a compound capable of inhibiting viral budding from the infected host cells. The methods are especially useful in treating HIV infection and in treating and preventing AIDS.
Abstract translation: 提供了用于抑制HIV传播和治疗HIV感染的方法，其包括向感染HIV的细胞施用能够从感染的宿主细胞抑制病毒出芽的化合物。 这些方法在治疗艾滋病毒感染和治疗和预防艾滋病方面特别有用。
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公开(公告)号：US20050222029A1
公开(公告)日：2005-10-06
申请号：US11075234
申请日：2005-03-07
Applicant: Paul Bartel , Daniel Cimbora , Janice Sugiyama , Daniel Wettstein , Karen Heichman
Inventor： Paul Bartel , Daniel Cimbora , Janice Sugiyama , Daniel Wettstein , Karen Heichman
IPC: A61K38/00 , A61K38/17 , C07K14/47 , C07K14/775 , G01N33/68
CPC classification number: G01N33/6893 , A61K38/00 , C07K14/775 , C07K2319/00 , C07K2319/70 , G01N2333/775 , G01N2500/00
Abstract: Protein complexes are provided comprising at least one interacting pair of proteins. The protein complexes are useful in screening assays for identifying compounds effective in modulating the protein complexes, and in treating and/or preventing diseases and disorders associated with the protein complexes and/or their constituent interacting members.
Abstract translation: 提供包含至少一个相互作用的蛋白质对的蛋白质复合物。 蛋白质复合物可用于鉴定化合物，用于鉴定有效调节蛋白质复合物的化合物，以及治疗和/或预防与蛋白质复合物和/或其组成相互作用成员相关的疾病和病症。
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公开(公告)号：US20100016586A1
公开(公告)日：2010-01-21
申请号：US12494917
申请日：2009-06-30
Applicant: ASHOK C. BAJJI , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
Inventor： ASHOK C. BAJJI , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
IPC: C07D413/14 , C07D473/34
CPC classification number: A61K31/52 , A61K31/522 , C07D473/34
Abstract: The invention relates to compounds of Formulae I-III and their therapeutic uses.
Abstract translation: 本发明涉及式I-III的化合物及其治疗用途。
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公开(公告)号：US07595401B2
公开(公告)日：2009-09-29
申请号：US11748362
申请日：2007-05-14
Applicant: Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
Inventor： Ashok C. Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark B. Anderson , Daniel Wettstein , Mark Shenderovich , John A. Vanecko
IPC: C07D473/34 , A61K31/52 , A61P35/00
CPC classification number: A61K31/52 , A61K31/522 , C07D473/34
Abstract: The invention relates to compounds of Formula I and their therapeutic uses, wherein substituent A is chosen from a substituted or unsubstituted aryl, heteroaryl, heterocyclic, or carboxylic group, B is chosen from a substituted or unsubstituted piperidine, homopiperidine, piperazine, pyrrolidine or azetidine group, R1 is chosen from hydro, alkyl, aryl, heteroaryl amino and halo, and L1 and L2 are as defined in the specification.
Abstract translation: 本发明涉及式I化合物及其治疗用途，其中取代基A选自取代或未取代的芳基，杂芳基，杂环或羧基，B选自取代或未取代的哌啶，高哌啶，哌嗪，吡咯烷或氮杂环丁烷 基团，R 1选自氢，烷基，芳基，杂芳基氨基和卤素，且L1和L2如说明书中所定义。
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公开(公告)号：US20070299258A1
公开(公告)日：2007-12-27
申请号：US11748362
申请日：2007-05-14
Applicant: Ashok Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark Anderson , Daniel Wettstein , Mark Shenderovich , John Vanecko
Inventor： Ashok Bajji , Se-Ho Kim , Benjamin Markovitz , Richard Trovato , Rajendra Tangallapally , Mark Anderson , Daniel Wettstein , Mark Shenderovich , John Vanecko
IPC: C07D473/00 , C07D413/06
CPC classification number: A61K31/52 , A61K31/522 , C07D473/34
Abstract: The invention relates to compounds of Formulae I-III and their therapeutic uses.
Abstract translation: 本发明涉及式I-III的化合物及其治疗用途。
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