公开(公告)号：US20100217138A1

公开(公告)日：2010-08-26

申请号：US12658897

申请日：2010-02-16

申请人： David Borsook ,  Lino Becerra ,  David Boas ,  Edward George

发明人： David Borsook ,  Lino Becerra ,  David Boas ,  Edward George

IPC分类号： A61B5/0265 ,  G06K9/00

CPC分类号： A61B5/0261 ,  A61B5/0042 ,  A61B5/14553 ,  A61B5/4821 ,  A61B2562/0233 ,  A61B2562/046

摘要： A method for recognizing awareness in a subject includes performing optical imaging on at least one cortical region of the brain of the subject. Optical imaging data are obtained over time measuring one or more hemodynamic parameters in the at least one cortical region of the subject's brain. An observed variation pattern is determined in the measured hemodynamic parameters, and the observed variation pattern is compared to one or more known variation patterns characteristic of awareness. Substantial similarity between the observed and known variation patterns signals awareness in the subject.

摘要翻译： 用于识别受试者意识的方法包括对受试者的脑的至少一个皮层区进行光学成像。 随着时间的推移，获得光学成像数据，测量受试者脑部的至少一个皮质区域中的一个或多个血液动力学参数。 在测量的血液动力学参数中确定观察到的变化模式，并将观察到的变化模式与一个或多个已知的变化模式进行比较，其特征在于意识。 观察到的和已知的变化模式之间的实质相似性表明了受试者的意识。

公开(公告)号：US10912504B2

公开(公告)日：2021-02-09

申请号：US15111721

申请日：2015-01-14

申请人： Canon U.S.A. Inc. ,  The General Hospital Corporation ,  Haruo Nakaji ,  Maria Angela Franceschini ,  David Boas ,  Erin Buckley ,  Pei-Yi Lin ,  Stefan Carp

发明人： Haruo Nakaji ,  Maria Angela Franceschini ,  David Boas ,  Erin Buckley ,  Pei-Yi Lin ,  Stefan Carp

IPC分类号： A61B5/1455 ,  A61B5/026 ,  A61B5/00 ,  A61B5/145

摘要： There is provided herewith an apparatus, probe, and method for the combination of near-infrared spectroscopy (NIRS) and diffuse correlation spectroscopy (DCS). The apparatus, probe and method allow for the simultaneous detection of NIRS and DCS.

公开(公告)号：US08951202B2

公开(公告)日：2015-02-10

申请号：US12658897

申请日：2010-02-16

申请人： David Borsook ,  Lino Becerra ,  David Boas ,  Edward George

发明人： David Borsook ,  Lino Becerra ,  David Boas ,  Edward George

IPC分类号： A61B5/02 ,  A61B5/026 ,  A61B5/1455 ,  A61B5/00

CPC分类号： A61B5/0261 ,  A61B5/0042 ,  A61B5/14553 ,  A61B5/4821 ,  A61B2562/0233 ,  A61B2562/046

摘要： A method for recognizing awareness in a subject includes performing optical imaging on at least one cortical region of the brain of the subject. Optical imaging data are obtained over time measuring one or more hemodynamic parameters in the at least one cortical region of the subject's brain. An observed variation pattern is determined in the measured hemodynamic parameters, and the observed variation pattern is compared to one or more known variation patterns characteristic of awareness. Substantial similarity between the observed and known variation patterns signals awareness in the subject.

摘要翻译： 用于识别受试者意识的方法包括对受试者的脑的至少一个皮层区进行光学成像。 随着时间的推移，获得光学成像数据，测量受试者脑部的至少一个皮质区域中的一个或多个血液动力学参数。 在测量的血液动力学参数中确定观察到的变化模式，并将观察到的变化模式与一个或多个已知的变化模式进行比较，其特征在于意识。 观察到的和已知的变化模式之间的实质相似性表明了受试者的意识。

公开(公告)号：US20080004531A1

公开(公告)日：2008-01-03

申请号：US11766444

申请日：2007-06-21

申请人： Stefan Carp ,  David Boas

发明人： Stefan Carp ,  David Boas

IPC分类号： A61B6/00

CPC分类号： A61B5/14551 ,  A61B5/0053 ,  A61B6/507

摘要： A cancer screening method includes changing a compression state of selected tissue; and obtaining a signal indicative of a response of an optical property of the selected tissue in response to the change in the compression state.

摘要翻译： 癌症筛选方法包括改变选定组织的压缩状态; 以及响应于压缩状态的变化而获得指示所选择的组织的光学特性的响应的信号。

公开(公告)号：US06985763B2

公开(公告)日：2006-01-10

申请号：US10466447

申请日：2001-11-30

申请人： David Boas ,  Maria Angela Franceschini ,  Sergio Fantini

发明人： David Boas ,  Maria Angela Franceschini ,  Sergio Fantini

IPC分类号： A61B5/00

CPC分类号： A61B5/6828 ,  A61B5/02152 ,  A61B5/08 ,  A61B5/0816 ,  A61B5/14551 ,  A61B5/14552 ,  A61B5/7257 ,  G01N21/314

摘要： A method for measuring venous oxygen saturation levels has steps of measuring optical absorption oscillation data at the respiratory frequency at a plurality of wavelengths (2). A reduced scattering coefficient and an absorption coefficient are determined for the tissue, with the result that an effective path length can be determined (6). Data processing is performed to calculate amplitudes for the absorption oscillation data that are translated into oxygenated and deoxygenated hemoglobin concentrations for the venous compartment (8). A method of the invention does not required mechanical ventilation devices or venous perturbation. Additional method steps may entail verifying that the measured absorption oscillation data results from the venous compartment.

摘要翻译： 用于测量静脉血氧饱和度水平的方法具有以多个波长测量呼吸频率的光吸收振荡数据的步骤（2）。 确定组织的降低的散射系数和吸收系数，结果可以确定有效的路径长度（6）。 进行数据处理以计算被转化为静脉隔室（8）的氧化和脱氧血红蛋白浓度的吸收振荡数据的振幅。 本发明的方法不需要机械通气装置或静脉扰动。 额外的方法步骤可能需要验证测量的吸收振荡数据是从静脉室产生的。