Abstract:
Over 40 common diseases, in addition to congestive heart failure (CHF) due to hypertension (HTN) or non-insulin dependent diabetes mellitus (type II diabetes mellitus) (NIDDM), atherosclerotic peripheral vascular disease (ASPVD) due to HTN or NIDDM, and chronic obstructive pulmonary disease; emphysema (COPD), are associated with the ACE D/D genotype and should also respond to an adequate tissue-inhibitory dose of ACE inhibitors such as quinapril. Several of these diseases have now been successfully treated using higher than normal dosages of ACE inhibitors, especially hydrophobic ACE inhibitors, with good outcomes. ACE inhibitors have also been found to be useful in inhibiting apoptosis and aging in general. Dosages that have been utilized are typically greater than quinapril at a dose of 40 to 80 mg/day, i.e. up to 1 mg/kg per day for a “typical” 80 kg patient. New formulations of ACE inhibitors have been developed for these higher dosages, including 80 mg tablets, controlled and/or sustained release formulations, and formulations containing a second active agent such as a diuretic, or a compound such as furosemide 20 mg/day (for creatinine 2.5 mg/dl), to prevent fluid retention and congestive heart failure in patients with renal failure. The ACE inhibitors can also be combined with an angiotensin receptor blocker.
Abstract:
The present invention provides a logically organized electronic program guide separated into categories. Each category has a theme. Inside each theme-based category there is a listing of television programming. In this way, the subscriber can locate a desired theme and then determine a desired program from the list in the category.
Abstract:
Methods are disclosed of making and of using a high density high strength titanium diboride comprising material. The method of making comprises (a) compacting a mixture of titanium diboride, 5-20% by weight of a metal group binder, and up to 1% oxygen and up to 2% graphite, the mixture having a maximum particle size of 5 microns, and (b) sintering the compact to substantially full density. The TiB.sub.2 may be replaced by up to 10% TiC. The method of use is as a cutting tool at relatively high speeds against aluminum based materials.
Abstract:
A protective cover for restricting access to the female sockets or connectors of an electrical outlet, thereby protecting infants and small children and others of limited understanding against electrical shock. The cover includes a base plate bearing an externally threaded boss which replaces the conventional outlet cover; a safety cap of the push-and-twist type threaded on the boss; protective members which are clamped by the safety cap against the boss overlying the socket being protected to deny access to the socket, both when the socket is in use and when it is not in service; and a platelike shield which normally overlies, and denies access to, a second female socket of the typical double socket wall outlet. This shield can be swung aside after backing off the safety cap to furnish unprotected, but controlled, and typically temporary, access to that second female socket.
Abstract:
A method of making Si.sub.3 N.sub.4 based cutting tools (and the resulting product) is disclosed. A mixture is formed of three powders: a first powder of at least 75% crystalline Si.sub.3 N.sub.4, a second powder selected from the group Y.sub.2 O.sub.3, MgO, CeO.sub.2 and ZrO.sub.2, and a third powder selected from the group consisting of Al.sub.2 O.sub.3, WC, Wsi.sub.2, W and TiC. The mixture is cold pressed to a density of 50-70% of theoretical and then sintered to full density without the application of pressure.
Abstract translation:公开了制造Si 3 N 4基切削工具(以及所得产品)的方法。 混合物由三种粉末形成:第一粉末为至少75%的结晶Si 3 N 4,第二粉末,其选自Y 2 O 3,MgO,CeO 2和ZrO 2,以及选自Al 2 O 3,WC,Wsi 2, W和TiC。 将混合物冷压至理论值的50-70%的密度,然后在不施加压力的情况下烧结至全密度。
Abstract:
A method of making cemented titanium carbide base cutting tools with increased tool life is disclosed. Substantially unoxidized carbide and binder metal powders are ground to a sub-micron particle size in the presence of a low-boiling oxidation-inhibiting ingredient covering the particles of said powders. A low-boiling pressing aid is added. The ground powders are then subjected to air drying to evaporate said oxidation inhibiting liquid ingredient and the pressing aid consisting preferably of polyethylene glycol. After compacting the waxed ground particles to a predetermined configuration, the compact is first heated to volatize the wax at an appropriate temperature and critically in the presence of a nitrogen based atmosphere which may contain 0-10% H.sub.2. The dewaxed compact is then heated to a higher second temperature level for effecting sintering in the presence of a vacuum.
Abstract:
A composition for a ceramic cutting tool which enjoys long tool life at high speed machining of ferrous alloys. The composition consists essentially of 60-80% alpha aluminum oxide (Al.sub.2 O.sub.3) having a hexagonal crystal structure and the remainder of titanium carbonitride (TiCN). The titanium carbonitride has a mixture of 30-70% titanium carbide and the remainder titanium nitride. The mixture is compacted and hot pressed, sintered or pressure sintered to form the tool.
Abstract translation:一种陶瓷切削工具的组合物,在铁合金的高速加工中具有较长的刀具寿命。 该组合物基本上由具有六方晶系结构的60-80%的α氧化铝(Al 2 O 3)和剩余的碳氮化钛(TiCN)组成。 碳氮化钛具有30-70%的碳化钛和其余的氮化钛的混合物。 将混合物压实并热压,烧结或加压烧结以形成工具。
Abstract:
Devices for protecting the bulb of a night light against damage and for denying access to the sockets of an electrical outlet into which the night light is plugged and for also denying access to those parts of the night light which might produce an electrical shock if touched. One component of the protective arrangement is a cover with externally threaded bosses which are apertured so that the night light can be plugged into a socket which a boss overlies by installing the night light through the aperture. The night light includes a bulb surrounding protective shield which is clamped against the boss by a safety cap of the push-and-twist type, thereby protecting the bulb and isolating the socket and electrically charged parts of the night light. Safety caps are also used to deny access to any othe sockets of the outlet servicing the night light, and these safety caps may be designed so that they will perform this function when the protected socket is in use as well as when it is out of service.
Abstract:
A cover for restricting access to the female sockets of an electrical outlet, thereby protecting infants and small children and others of limited understanding against electrical shock. The cover includes a plate bearing externally threaded bosses which replaces the conventional outlet cover, safety caps of the push-and-twist type, and protective members which are clamped against the boss overlying the socket being protected by the safety cap to deny access to the socket, both when the socket is in use and when it is not in service.