公开(公告)号：US20160256059A1

公开(公告)日：2016-09-08

申请号：US15060970

申请日：2016-03-04

申请人： Dmytro Volkov ,  Valerij Boyko ,  Alexander Bakai

发明人： Dmytro Volkov ,  Valerij Boyko ,  Alexander Bakai

IPC分类号： A61B5/02 ,  A61B6/00 ,  A61B6/03 ,  A61B5/055 ,  A61B8/06 ,  A61M5/00

CPC分类号： A61B6/504 ,  A61B5/0263 ,  A61B5/055 ,  A61B6/032 ,  A61B6/503 ,  A61B6/5217 ,  A61B8/06 ,  A61B8/0883 ,  A61B8/5223 ,  A61B2576/00 ,  A61M5/007 ,  G06T7/0016 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20224 ,  G06T2207/30104

摘要： A medical diagnostic system includes an image processor to generate a differential frame from two consecutive medical images of the heart based on difference in pixel-by-pixel brightness of the consecutive images. A brightness segmentation image having a plurality of brightness zones is generated based of the differential frame. From the brightness zones, a turbulence index is calculated based on the iso-contour and the area in each brightness zone. The turbulence index is a quantitative representation of a degree of turbulence in the blood flow which can be used to generate a prognosis and/or diagnosis of cardiac function.

摘要翻译： 医疗诊断系统包括图像处理器，用于基于连续图像的逐像素亮度的差异从心脏的两个连续的医学图像生成差分帧。 基于差分帧生成具有多个亮度区域的亮度分割图像。 从亮度区域，基于等高线和每个亮度区域的面积计算湍流指数。 湍流指数是可以用于产生心脏功能的预后和/或诊断的血流中湍流程度的定量表示。

公开(公告)号：US09676620B1

公开(公告)日：2017-06-13

申请号：US13044746

申请日：2011-03-10

申请人： Igor Sokolov ,  Eun-Bum Cho ,  Dmytro Volkov

发明人： Igor Sokolov ,  Eun-Bum Cho ,  Dmytro Volkov

IPC分类号： B82Y40/00 ,  B82Y5/00 ,  A61K8/11 ,  A61K47/02 ,  B82Y30/00 ,  A61K9/51

CPC分类号： B82Y5/00 ,  A61K8/0279 ,  A61K8/11 ,  A61K8/25 ,  A61K8/585 ,  A61K9/5115 ,  A61K47/02 ,  A61K2800/413 ,  A61K2800/434 ,  A61Q1/02 ,  B82Y30/00 ,  B82Y40/00 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/64 ,  C01P2006/17 ,  C09C1/30 ,  C09C1/3063 ,  C09K11/06 ,  C09K11/592

摘要： The invention generally relates to fluorescent particles and more specifically to silica-based fluorescent nanoporous particles with physically encapsulated organic dyes. In one aspect of the invention, the nanoporous architecture provides a significant enhancement in fluorescence of the particles brightness compared to free dye. A particular chemical control of the silica matrix prevents the dye molecules from leaking the particles.