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公开(公告)号:US08109868B2
公开(公告)日:2012-02-07
申请号:US12830965
申请日:2010-07-06
IPC分类号: A61F2/00
CPC分类号: A61F2/2481
摘要: A highly compliant and elastic cardiac support device is provided. The device is constructed from a biocompatible material is applied to an external surface of a heart. The device can be used to resist dilatation of the heart, to provide acute wall support, or to enhance reduction in the size of the heart using stored potential energy, without interfering with systolic contraction.
摘要翻译: 提供高度兼容和弹性的心脏支持装置。 该装置由生物相容性材料构成,被施加到心脏的外表面。 该装置可以用于抵抗心脏的扩张,提供急性壁支持,或者使用储存的势能增强心脏尺寸的减小,而不会干扰收缩期的收缩。
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公开(公告)号:US5968092A
公开(公告)日:1999-10-19
申请号:US083341
申请日:1998-05-22
CPC分类号: A61F2/82 , A61F2/88 , A61L31/041 , A61L31/044 , A61L31/047 , A61L31/148 , A61L31/16 , A61F2/958 , A61F2210/0004 , A61F2210/0023 , A61F2250/0067 , A61F2250/0068 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2300/622 , Y10S623/901
摘要: A method for making a biodegradable stent for insertion into a lumen, the method involves the casting of a film including a matrix of collagen IV and laminin, drying the film, casting a film containing polylactic acid onto the first dried film to form stent material, drying the material formed and forming the biodegradable material into a stent.
摘要翻译: 一种生物可降解支架用于插入内腔的方法,该方法包括将包含胶原IV和层粘连蛋白基质的膜流延,干燥该膜,将含有聚乳酸的膜浇铸到第一干燥膜上以形成支架材料, 将形成的材料干燥并将可生物降解材料形成支架。
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公开(公告)号:US20110166413A1
公开(公告)日:2011-07-07
申请号:US13049499
申请日:2011-03-16
申请人: Clifton A. ALFERNESS , Donald G. ROHRBAUGH , James Edward SHAPLAND , Michael J. GIRARD , Donald F. PALME, II , James E. COX
发明人: Clifton A. ALFERNESS , Donald G. ROHRBAUGH , James Edward SHAPLAND , Michael J. GIRARD , Donald F. PALME, II , James E. COX
IPC分类号: A61F2/00
CPC分类号: A61F2/2481 , Y10S623/904
摘要: A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译: 生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积,以将其插入体积中并使护套滑过心脏。 护套具有在上下端之间的纵向尺寸,足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端 。 护套适于固定在心脏上,护套至少围绕瓣膜环和心室下肢。 护套在心脏上是可调节的,以贴合地符合心脏的外部几何形状,并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张,并允许心脏收缩期间不受阻碍的收缩 。
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公开(公告)号:US07806925B2
公开(公告)日:2010-10-05
申请号:US11041027
申请日:2005-01-21
IPC分类号: A61F2/06
CPC分类号: A61F2/82 , A61F2/88 , A61F2/958 , A61F2210/0004 , A61F2210/0023 , A61F2250/0067 , A61F2250/0068 , A61L31/041 , A61L31/044 , A61L31/047 , A61L31/148 , A61L31/16 , A61L2300/42 , A61L2300/604 , A61L2300/606 , A61L2300/622 , Y10S623/901 , C08L67/04
摘要: A stent includes a main body of a generally tubular shape for insertion into a lumen of a vessel of a living being. The tubular main body includes a substantially biodegradable matrix having collagen IV and laminin that enclose voids within the matrix. The tubular main body also includes a biodegradable strengthening material in contact with the matrix to strengthen the matrix. The tubular main body is essentially saturated with drugs.
摘要翻译: 支架包括用于插入活体血管内腔的大体管状形状的主体。 管状主体包括基本上可生物降解的基质,其具有包围基质内的空隙的胶原IV和层粘连蛋白。 管状主体还包括与基质接触以增强基质的可生物降解的强化材料。 管状主体基本上被药物饱和。
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公开(公告)号:US06482146B1
公开(公告)日:2002-11-19
申请号:US09593251
申请日:2000-06-13
申请人: Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
发明人: Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
IPC分类号: A61F200
CPC分类号: A61F2/2481 , Y10S623/904
摘要: A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
摘要翻译: 生物相容材料的护套具有尺寸设计用于心脏顶点的内部容积,以将其插入体积中并使护套滑过心脏。 护套具有在上下端之间的纵向尺寸,足以使护套围绕心脏的下部围绕心脏的瓣膜环并且进一步围绕下部以至少覆盖心脏的心室下端 。 护套适于固定在心脏上,护套至少围绕瓣膜环和心室下肢。 护套在心脏上是可调节的,以贴合地符合心脏的外部几何形状,并假设护套的最大调节体积以约束舒张期心脏超过最大调节体积的周向扩张,并允许心脏收缩期间不受阻碍的收缩 。
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公开(公告)号:US06270515B1
公开(公告)日:2001-08-07
申请号:US08805633
申请日:1997-02-26
IPC分类号: A61B1708
CPC分类号: A61L31/16 , A61B17/0057 , A61B2017/00557 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00601 , A61B2017/00606 , A61B2017/00615 , A61L31/04 , A61L31/044 , A61L31/048 , A61L31/06 , A61L31/14 , A61L31/148 , A61L2300/412 , A61L2300/414 , C08L85/02 , C08L67/04 , C08L75/04
摘要: A device for closing off a septal defect including a polymeric self-hardening material in a specific conformation which is delivered by a catheter means to the area of defect either directly on the cardiac tissue or into a balloon which spans both surfaces of the defect, and hardened in-situ by change in pH or ionic concentration, organic solvents, by permeation of a secondary material capable of precipitation, or by exposure to heat, light or laser energy. In blood, the device may be hardened through photopolymerization or a cooperative effect of coagulation, precipitation or ionization. The device can be made of biodegradable material impregnated with growth factors, mitogenic factors or other determinants which can improve tissue growth such that tissue ingrowth can occur over a period of time. The catheter itself may be an ultrasonic imaging catheter.
摘要翻译: 一种用于闭合中隔缺损的装置,其包括特定构象中的聚合物自硬化材料,其通过导管装置直接在心脏组织或跨越缺损的两个表面的气囊中传递到缺陷区域;以及 通过pH或离子浓度的变化,有机溶剂,能够沉淀的二次材料的渗透,或通过暴露于热,光或激光能量而原位硬化。 在血液中,可以通过光聚合或凝结,沉淀或离子化的协同作用使装置硬化。 该装置可以由浸有生长因子,促有丝分裂因子或其他决定因素的可生物降解材料制成,其可以改善组织生长,使得组织向内生长可以在一段时间内发生。 导管本身可以是超声成像导管。
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公开(公告)号:US20120136201A1
公开(公告)日:2012-05-31
申请号:US13367255
申请日:2012-02-06
IPC分类号: A61F2/00
CPC分类号: A61F2/2481
摘要: A highly compliant and elastic cardiac support device is provided. The device is constructed from a biocompatible material is applied to an external surface of a heart. The device can be used to resist dilatation of the heart, to provide acute wall support, or to enhance reduction in the size of the heart using stored potential energy, without interfering with systolic contraction.
摘要翻译: 提供高度兼容和弹性的心脏支持装置。 该装置由生物相容性材料构成,被施加到心脏的外表面。 该装置可以用于抵抗心脏的扩张,提供急性壁支持,或者使用储存的势能增强心脏尺寸的减小,而不会干扰收缩期的收缩。
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公开(公告)号:US20100274075A1
公开(公告)日:2010-10-28
申请号:US12830965
申请日:2010-07-06
IPC分类号: A61F2/00
CPC分类号: A61F2/2481
摘要: A highly compliant and elastic cardiac support device is provided. The device is constructed from a biocompatible material is applied to an external surface of a heart. The device can be used to resist dilatation of the heart, to provide acute wall support, or to enhance reduction in the size of the heart using stored potential energy, without interfering with systolic contraction.
摘要翻译: 提供高度兼容和弹性的心脏支持装置。 该装置由生物相容性材料构成,被施加到心脏的外表面。 该装置可以用于抵抗心脏的扩张,提供急性壁支持,或者使用储存的势能增强心脏尺寸的减小,而不会干扰收缩期的收缩。
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公开(公告)号:US07499757B2
公开(公告)日:2009-03-03
申请号:US10971577
申请日:2004-10-22
申请人: M. Sean Coe , Ronald W. Heil, Jr. , Peter T. Kelley , Jason Alan Shiroff , Randy W. Westlund , Donald F. Palme, II
发明人: M. Sean Coe , Ronald W. Heil, Jr. , Peter T. Kelley , Jason Alan Shiroff , Randy W. Westlund , Donald F. Palme, II
IPC分类号: A61N1/05
CPC分类号: A61B17/0469 , A61B5/0492 , A61B17/06109 , A61B2017/0417 , A61B2017/06042 , A61B2017/0608 , A61N1/0568 , A61N1/0587 , A61N2001/0578 , A61N2001/058
摘要: A myocardial lead attachment system for securing a distal end of a lead within a myocardium of a patient's heart. The system includes a lead body, an anchor mechanism formed of a bioabsorbable or biodegradable polymer for engaging a surface of the patient's heart and a surface feature formed on a portion of the lead body for promoting formation of scar tissue around said portion of the lead body.
摘要翻译: 用于将铅的远端固定在患者心脏的心肌内的心肌引线附着系统。 该系统包括引线体,由生物可吸收或可生物降解的聚合物形成的锚固机构,用于接合患者心脏的表面,以及形成在引线体的一部分上的表面特征,用于促进在引线体的所述部分周围形成瘢痕组织 。
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公开(公告)号:US06902524B2
公开(公告)日:2005-06-07
申请号:US10716020
申请日:2003-11-17
申请人: Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
发明人: Clifton A. Alferness , Donald G. Rohrbaugh , J. Edward Shapland , Michael J. Girard , Donald F. Palme, II , James E. Cox
CPC分类号: A61F2/2481 , Y10S623/904
摘要: A jacket of biological compatible material has an internal volume dimensioned for an apex of the heart to be inserted into the volume and for the jacket to be slipped over the heart. The jacket has a longitudinal dimension between upper and lower ends sufficient for the jacket to surround a lower portion of the heart with the jacket surrounding a valvular annulus of the heart and further surrounding the lower portion to cover at least the ventricular lower extremities of the heart. The jacket is adapted to be secured to the heart with the jacket surrounding at least the valvular annulus and the ventricular lower extremities. The jacket is adjustable on the heart to snugly conform to an external geometry of the heart and assume a maximum adjusted volume for the jacket to constrain circumferential expansion of the heart beyond the maximum adjusted volume during diastole and to permit unimpeded contraction of the heart during systole.
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