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公开(公告)号：US09957254B2
公开(公告)日：2018-05-01
申请号：US15320815
申请日：2015-07-02
申请人： Christopher M. Adams , David B. Belanger , Doug Bevan , Philippe Bolduc , Takeru Ehara , Luciana Ferrara , Nan Ji , Mitsunori Kato , Erik Meredith , Muneto Mogi , James J. Powers , Ganesh Prasanna
发明人： Christopher M. Adams , David B. Belanger , Doug Bevan , Philippe Bolduc , Takeru Ehara , Luciana Ferrara , Nan Ji , Mitsunori Kato , Erik Meredith , Muneto Mogi , James J. Powers , Ganesh Prasanna
IPC分类号： C07D401/14 , C07D401/04
CPC分类号： C07D401/14 , A61K31/4545 , A61K31/4985 , A61K31/519 , A61K31/53 , A61K45/06 , C07D401/04 , C07D401/12 , A61K2300/00
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号：US09765067B2
公开(公告)日：2017-09-19
申请号：US15320813
申请日：2015-07-02
申请人： Christopher M. Adams , David B. Belanger , Doug Bevan , Takeru Ehara , Luciana Ferrara , Nan Ji , Donglei Liu , Erik Meredith , Muneto Mogi , James Powers , Ganesh Prasanna , Mitsunori Kato
发明人： Christopher M. Adams , David B. Belanger , Doug Bevan , Takeru Ehara , Luciana Ferrara , Nan Ji , Donglei Liu , Erik Meredith , Muneto Mogi , James Powers , Ganesh Prasanna , Mitsunori Kato
IPC分类号： A61K31/4545 , A61K31/4725 , A61K31/4439 , C07D409/14 , A61K9/00
CPC分类号： C07D409/14 , A61K9/0048 , A61K31/4439 , A61K31/4545 , A61K31/4725
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号：US20170197950A1
公开(公告)日：2017-07-13
申请号：US15320813
申请日：2015-07-02
申请人： Christopher M. ADAMS , David B. BELANGER , Doug BEVAN , Takeru EHARA , Luciana FERRARA , Nan JI , Donglei LIU , Erik MEREDITH , Muneto MOGI , James POWERS , Ganesh PRASANNA , Mitsunori KATO
发明人： Christopher M. ADAMS , David B. BELANGER , Doug BEVAN , Takeru EHARA , Luciana FERRARA , Nan JI , Donglei LIU , Erik MEREDITH , Muneto MOGI , James POWERS , Ganesh PRASANNA , Mitsunori KATO
IPC分类号： C07D409/14 , A61K31/4439 , A61K31/4725 , A61K9/00 , A61K31/4545
CPC分类号： C07D409/14 , A61K9/0048 , A61K31/4439 , A61K31/4545 , A61K31/4725
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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4.发明申请公开(公告)号：US20170197940A1
公开(公告)日：2017-07-13
申请号：US15320810
申请日：2015-07-02
申请人： Christopher M. ADAMS , Doug BEVAN , Michael Paul CAPPARELLI , Takeru EHARA , Luciana FERRARA , Nan JI , Mitsunori KATO , Nello MAINOLFI , Erik MEREDITH , Muneto MOGI , James J. POWERS , Ganesh PRASANNA
发明人： Christopher M. ADAMS , Doug BEVAN , Michael Paul CAPPARELLI , Takeru EHARA , Luciana FERRARA , Nan JI , Mitsunori KATO , Nello MAINOLFI , Erik MEREDITH , Muneto MOGI , James J. POWERS , Ganesh PRASANNA
IPC分类号： C07D401/14 , C07D401/12 , A61K31/454 , C07D413/14 , A61K31/4725 , A61K31/4439 , C07D405/14 , A61K9/00 , A61K31/4545
CPC分类号： C07D401/14 , A61K9/0048 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/4725 , C07D401/10 , C07D401/12 , C07D405/14 , C07D413/14
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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5.发明授权公开(公告)号：US10208018B2
公开(公告)日：2019-02-19
申请号：US15320810
申请日：2015-07-02
申请人： Christopher M. Adams , Doug Bevan , Michael Paul Capparelli , Takeru Ehara , Luciana Ferrara , Nan Ji , Mitsunori Kato , Nello Mainolfi , Erik Meredith , Muneto Mogi , James J. Powers , Ganesh Prasanna
发明人： Christopher M. Adams , Doug Bevan , Michael Paul Capparelli , Takeru Ehara , Luciana Ferrara , Nan Ji , Mitsunori Kato , Nello Mainolfi , Erik Meredith , Muneto Mogi , James J. Powers , Ganesh Prasanna
IPC分类号： C07D401/04 , C07D401/14 , C07D413/14 , C07D401/10 , C07D401/12 , A61K9/00 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/4725 , C07D405/14
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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公开(公告)号：US20170197941A1
公开(公告)日：2017-07-13
申请号：US15320815
申请日：2015-07-02
申请人： Christopher M. ADAMS , David B. BELANGER , Doug BEVAN , Philippe BOLDUC , Takeru EHARA , Luciana FERRARA , Nan JI , Mitsunori KATO , Erik MEREDITH , Muneto MOGI , James J. POWERS , Ganesh PRASANNA
发明人： Christopher M. ADAMS , David B. BELANGER , Doug BEVAN , Philippe BOLDUC , Takeru EHARA , Luciana FERRARA , Nan JI , Mitsunori KATO , Erik MEREDITH , Muneto MOGI , James J. POWERS , Ganesh PRASANNA
IPC分类号： C07D401/14 , C07D401/04
CPC分类号： C07D401/14 , A61K31/4545 , A61K31/4985 , A61K31/519 , A61K31/53 , A61K45/06 , C07D401/04 , C07D401/12 , A61K2300/00
摘要： The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.
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