公开(公告)号：US20050021088A1

公开(公告)日：2005-01-27

申请号：US10493874

申请日：2002-10-29

申请人： Peter Schuler ,  Douglas Gwost ,  \Wolfgang Daum ,  Robert Schwartz

发明人： Peter Schuler ,  Douglas Gwost ,  \Wolfgang Daum ,  Robert Schwartz

IPC分类号： A61B18/08 ,  A61N1/00 ,  H05B11/00

CPC分类号： A61B18/04 ,  A61B2017/22001 ,  A61B2018/00107 ,  A61B2018/00345 ,  A61B2018/00595 ,  A61N1/406

摘要： Disclosed are systems for the application of heat to an area of the body of a mammal, a system including a device fabricated from or coated with a material comprising of a non-metal matrix and susceptor particles, a non-invasive inductor and magnetic circuit for heating the particles by transmitting an alternating magnetic field (AMF), and an alternating current generator that provides an alternating current to the inductor. Also disclosed are methods related to the non-invasive application of heat to mammalian tissue. These systems and methods are useful where heat must be applied in a controlled manner to avoid undesired damage to tissue.

摘要翻译： 公开了一种用于向哺乳动物身体区域施加热量的系统，包括由包含非金属基体和感受体颗粒的材料制成或涂覆的装置的系统，非侵入式电感器和用于 通过传递交变磁场（AMF）来加热颗粒，以及向电感器提供交流电的交流发电机。 还公开了与将热量非侵入性施用于哺乳动物组织有关的方法。 这些系统和方法在必须以受控方式施加热量以避免对组织的不期望的损伤的情况下是有用的。

公开(公告)号：US20050090732A1

公开(公告)日：2005-04-28

申请号：US10696399

申请日：2003-10-28

申请人： Robert Ivkov ,  Wolfgang Daum ,  Allan Foreman ,  Douglas Gwost

发明人： Robert Ivkov ,  Wolfgang Daum ,  Allan Foreman ,  Douglas Gwost

IPC分类号： A61B5/055 ,  A61N20060101 ,  A61N1/40 ,  A61N2/00 ,  A61N5/04 ,  A61N5/06 ,  A61N5/10

CPC分类号： A61N1/406 ,  A61N2/002 ,  A61N2/008 ,  A61N5/04 ,  A61N5/062 ,  A61N5/10

摘要： Disclosed are compositions, systems and methods for treating a subject's body, body part, tissue, body fluid cells, pathogens, or other undesirable matter involving the administration of a targeted thermotherapy that comprises a bioprobe (energy susceptive materials that are attached to a target-specific ligand). Such targeted therapy methods can be combined with at least one other therapy technique. Other therapies include hyperthermia, direct antibody therapy, radiation, chemo- or pharmaceutical therapy, photodynamic therapy, surgical or interventional therapy, bone marrow or stem cell transplantation, and medical imaging, such as MRI, PET, SPECT, and bioimpedance. The disclosed therapies may be useful in the treatment of a variety of indications, including but not limited to, cancer of any type, such as bone marrow, lung, vascular, neuro, colon, ovarian, breast and prostate cancer, epitheleoid sarcomas, AIDS, adverse angiogenesis, restenosis, amyloidosis, tuberculosis, cardiovascular plaque, vascular plaque, obesity, malaria, and illnesses due to viruses, such as HIV.

摘要翻译： 公开了用于治疗受试者的身体，身体部位，组织，体液细胞，病原体或涉及施用靶向热疗法的其它不期望的物质的组合物，系统和方法，其包括生物探针（附着于靶 - 特异性配体）。 这样的靶向治疗方法可以与至少一种其它治疗技术组合。 其他疗法包括热疗，直接抗体治疗，放射治疗，化疗或药物治疗，光动力疗法，手术或介入治疗，骨髓或干细胞移植，以及医学成像，如MRI，PET，SPECT和生物阻抗。 所公开的疗法可用于治疗各种适应症，包括但不限于任何类型的癌症，例如骨髓，肺，血管，神经，结肠，卵巢，乳腺和前列腺癌，上皮样肉瘤，AIDS ，不良血管生成，再狭窄，淀粉样变性，结核病，心血管斑块，血管斑块，肥胖症，疟疾和由于病毒如HIV引起的疾病。