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公开(公告)号：US07083643B2
公开(公告)日：2006-08-01
申请号：US10388741
申请日：2003-03-17
申请人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
发明人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61B17/00491 , A61B17/12022 , A61B17/12118 , A61B17/12186 , A61B2017/00495 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2002/823 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61L24/043 , A61M25/1011 , A61M2025/1013 , A61M2025/105 , A61M2025/1086 , Y10S623/903
摘要： This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.
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公开(公告)号：US06645167B1
公开(公告)日：2003-11-11
申请号：US09574500
申请日：2000-05-19
申请人： Thomas J. Whalen, II , Chinh Ngoc Tran , Douglas Ray Hayman , Noah Michael Roth , Jacques Moret , Richard J. Greff
发明人： Thomas J. Whalen, II , Chinh Ngoc Tran , Douglas Ray Hayman , Noah Michael Roth , Jacques Moret , Richard J. Greff
IPC分类号： A61F200
CPC分类号： A61K49/0419 , A61K9/0024 , A61L24/001 , A61L24/046 , A61L24/06 , A61L24/08 , A61L2430/36 , A61M5/31586 , A61M2025/1052 , C08J3/091 , C08L29/04
摘要： Disclosed are novel methods for embolizing blood vessels comprising delivering, via a catheter, an embolic composition comprising a biocompatible polymer, a biocompatible water insoluble contrast agent, and a biocompatible solvent. In one embodiment, the method is conducted during a single surgical procedure whereby a flow-arresting device is positioned and activated at the vascular site to be embolized, the embolic composition is injected, and the flow-arresting device is deactivated. In another embodiment, the method is conducted during a single surgical procedure whereby two embolic compositions, situated adjacent to one another, are injected at the vascular site to be embolized.
摘要翻译： 公开了用于栓塞血管的新颖方法，包括通过导管递送包含生物相容性聚合物，生物相容性水不溶性造影剂和生物相容性溶剂的栓塞组合物。 在一个实施方案中，该方法在单次外科手术过程中进行，由此在要栓塞的血管部位定位并激活止血装置，注射栓塞组合物，并且阻流装置停用。 在另一个实施方案中，该方法在单次外科手术过程中进行，由此彼此相邻的两个栓塞组合物被注射到待栓塞的血管部位。
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公开(公告)号：US08486046B2
公开(公告)日：2013-07-16
申请号：US13046477
申请日：2011-03-11
申请人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
发明人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
IPC分类号： A61M31/00
CPC分类号： A61M25/104 , A61B6/12 , A61B17/00491 , A61B17/12022 , A61B17/1204 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/22067 , A61M25/0108 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0004 , A61M2025/1045 , A61M2025/1052
摘要： A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.
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4.发明授权公开(公告)号：US08235941B2
公开(公告)日：2012-08-07
申请号：US11868049
申请日：2007-10-05
申请人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
发明人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
CPC分类号： A61M25/104 , A61B6/12 , A61B17/00491 , A61B17/12022 , A61B17/1204 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/22067 , A61M25/0108 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0004 , A61M2025/1045 , A61M2025/1052
摘要： A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.
摘要翻译： 用于治疗复杂脉管系统的导管（例如分叉动脉瘤）在其远端部分设置有可充气气囊。 可选择气囊的形状，位置和材料，使得当充气时，球囊符合复杂脉管系统的形状，或其至少一部分，而不会使容器壁明显变形。 以这种方式，气囊可以用于控制脉管系统中的流动，例如在引入材料期间闭塞脉管系统的选定分支，以便集中材料并最小化其血流量的支付。
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5.发明授权公开(公告)号：US08066667B2
公开(公告)日：2011-11-29
申请号：US10235064
申请日：2002-09-04
申请人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
发明人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
IPC分类号： A61M31/00
CPC分类号： A61M25/104 , A61B6/12 , A61B17/00491 , A61B17/12022 , A61B17/1204 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/22067 , A61M25/0108 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0004 , A61M2025/1045 , A61M2025/1052
摘要： A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.
摘要翻译： 用于治疗复杂脉管系统的导管（例如分叉动脉瘤）在其远端部分设置有可充气气囊。 可选择气囊的形状，位置和材料，使得当充气时，球囊符合复杂脉管系统的形状，或其至少一部分，而不会使容器壁明显变形。 以这种方式，气囊可以用于控制脉管系统中的流动，例如在引入材料期间封闭脉冲系统的选定分支，以便集中材料并最小化其由血流量的支付。
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公开(公告)号：US06569190B2
公开(公告)日：2003-05-27
申请号：US09811423
申请日：2001-03-20
申请人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
发明人： Thomas J. Whalen, II , Richard J. Greff , Kevin P. Gilmartin , Douglas Ray Hayman , Todd J. Hewitt , Ed L. Olson , Mark A. Pecor , Earl H. Slee , George Wallace
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61B17/00491 , A61B17/12022 , A61B17/12118 , A61B17/12186 , A61B2017/00495 , A61F2/86 , A61F2/90 , A61F2/91 , A61F2002/823 , A61F2230/0054 , A61F2250/0018 , A61F2250/0039 , A61L24/043 , A61M25/1011 , A61M2025/1013 , A61M2025/105 , A61M2025/1086 , Y10S623/903
摘要： This invention is directed to methods for treating aneurysms wherein the aneurysmal sac is filled with a non-particulate agent or plurality of such agents and/or with a fluid composition which solidifies in situ. Filling of the aneurysmal sac employs sufficient amount of the non-particulate agent or plurality of such agents and/or the fluid composition to inhibit blood flow into the aneurysm sac. In addition, the methods of this invention also provide for non-endogenous isolation of the parent artery proximal and distal to the aneurysmal sac from systemic blood flow of the treated mammal. The combination of these features provides for treatment of the aneurysmal sac while, at the same time, inhibiting aneurysm formation and/or regrowth in the diseased portions of the arterial wall proximal and distal to the treated aneurysm.
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公开(公告)号：US06503244B2
公开(公告)日：2003-01-07
申请号：US09801480
申请日：2001-03-07
申请人： Douglas Ray Hayman
发明人： Douglas Ray Hayman
IPC分类号： A61M2500
CPC分类号： A61M25/0097 , A61J1/201 , A61J1/2044 , A61J1/2058 , A61J1/2096 , A61J2200/10 , A61M25/0052 , A61M25/0054 , A61M2025/0098
摘要： A catheter and system for delivering viscous fluid, under high pressures, into the vasculature of a patient includes a catheter body having a proximal end and a distal end, a reinforcing member surrounding at least a portion of the proximal end, and a compression fitting surrounding the reinforcing member for holding the proximal end of the catheter body. A strain relief element shrouds a portion of the proximal end to prevent kinking of the catheter body. Accordingly, the reinforcing member, the compression fitting and the strain relief element cooperate to hold the catheter body in a luer fitting and to prevent the proximal end of the catheter body from kinking under bending, and to prevent leakage or bursting under pressure.
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8.发明申请公开(公告)号：US20110245802A1
公开(公告)日：2011-10-06
申请号：US13046477
申请日：2011-03-11
申请人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
发明人： Douglas Ray Hayman , Peter Gregory Davis , Maria De Jesus Sanson , Komonn Lim Reedy , Todd Jeffrey Hewitt
CPC分类号： A61M25/104 , A61B6/12 , A61B17/00491 , A61B17/12022 , A61B17/1204 , A61B17/12113 , A61B17/12136 , A61B17/12186 , A61B2017/1205 , A61B2017/22067 , A61M25/0108 , A61M25/09 , A61M25/10 , A61M25/1002 , A61M2025/0004 , A61M2025/1045 , A61M2025/1052
摘要： A catheter used for treatment of complex vasculature, such as a bifurcated aneurysm, is provided with an inflatable balloon at a distal portion thereof. The shape, location and material of the inflatable balloon are selected such that when inflated, the balloon conforms to the shape of the complex vasculature, or at least a portion thereof, without appreciably deforming the vessel walls. In this manner, the balloon can be used to control flow in the vasculature, for example occluding a selected branch of the vasculature during introduction of material in order concentrate the material and minimize its disbursement by blood flow.
摘要翻译： 用于治疗复杂脉管系统的导管（例如分叉动脉瘤）在其远端部分设置有可充气气囊。 可选择气囊的形状，位置和材料，使得当充气时，球囊符合复杂脉管系统的形状，或其至少一部分，而不会使容器壁明显变形。 以这种方式，气囊可以用于控制脉管系统中的流动，例如在引入材料期间闭塞脉管系统的选定分支，以便集中材料并最小化其血流量的支付。
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9.发明授权Methods for delivering in vivo uniform dispersed embolic compositions of high viscosity 有权用于递送高粘度的均匀分散栓塞组合物的方法公开(公告)号：US06454738B1
公开(公告)日：2002-09-24
申请号：US09574963
申请日：2000-05-19
IPC分类号： A61M3100
CPC分类号： C08J3/091 , A61K49/0419 , A61L24/001 , A61L24/046 , A61L24/06 , A61L24/08 , A61L2430/36 , A61M2025/1052 , C08L29/04
摘要： Disclosed are novel techniques for embolizing blood vessels which are particularly suited for treating vascular lesions via catheter delivery of an embolic composition.
摘要翻译： 公开了用于栓塞血管的新技术，其特别适用于通过栓塞组合物的导管递送治疗血管病变。
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