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1.发明申请公开(公告)号：US20060229570A1
公开(公告)日：2006-10-12
申请号：US11102882
申请日：2005-04-11
申请人： John Lovell , Robert West , Todd Chelak , William Easterbrook , Mark Follman , Edward Browka
发明人： John Lovell , Robert West , Todd Chelak , William Easterbrook , Mark Follman , Edward Browka
IPC分类号： A61M5/315
CPC分类号： A61M5/20 , A61M5/28 , A61M5/315 , A61M5/31551 , A61M5/31561 , A61M5/31571 , A61M5/3158 , A61M5/31593 , A61M5/3202 , A61M5/46 , A61M2005/2013
摘要： An injectable substance delivery device comprising a pen device body, a cartridge, a plunger, a drive mechanism, and at least one of a lock-out mechanism and a rate-limiting mechanism. The lock-out mechanism is provided through a ratchet engagement between the body and the plunger to restrict plunger movement and to ensure that the required needle puncture depth is realized prior to injection by locking out the injection mechanism from advancing until a specified force is applied to the skin. A rate-limiting mechanism is also provided through a user compressed plunger drive spring to ensure that a specific rate of injection is realized during the injection of a medicament.
摘要翻译： 一种可注射物质输送装置，包括笔装置主体，盒，柱塞，驱动机构，以及锁定机构和速率限制机构中的至少一个。 通过主体和柱塞之间的棘轮接合来提供锁定机构以限制柱塞运动，并且确保在注射之前通过锁定注射机构而推进所需的针穿刺深度直到施加特定的力 皮。 还通过用户压缩的柱塞驱动弹簧提供速率限制机构，以确保在注射药物期间实现特定的注射速率。
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公开(公告)号：US20130102992A1
公开(公告)日：2013-04-25
申请号：US13573753
申请日：2012-10-03
申请人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
发明人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
IPC分类号： A61J1/20
CPC分类号： B65D25/20 , A61J1/10 , A61J1/1462 , A61J1/201 , A61J1/2041 , A61J1/2068 , A61J1/2089 , B65B3/003 , Y10T137/9029
摘要： A port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a port housing for connection to a second container, and a retainer for connection to a first container, wherein the retainer rotates relative to the port housing and is constructed to move axially within the port housing. An actuator is axially fixed within the port housing and forces a stopper associated with a first container into a first container when the retainer moves axially within the port housing upon rotation of the retainer relative to the port housing. The assembly is configured to establish fluid communication between a first container and a second container upon rotation of the retainer relative to the port housing.
摘要翻译： 一种用于在第一容器和第二容器之间建立流体连通的端口组件。 端口组件包括用于连接到第二容器的端口壳体和用于连接到第一容器的保持器，其中保持器相对于端口壳体旋转并且构造成在端口壳体内轴向移动。 当保持器相对于端口壳体旋转时，当保持器在端口壳体内轴向移动时，致动器轴向地固定在端口壳体内并且将与第一容器相关联的止动件推入第一容器中。 组件被构造成在保持器相对于端口壳体旋转时，在第一容器和第二容器之间建立流体连通。
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公开(公告)号：US09079686B2
公开(公告)日：2015-07-14
申请号：US13573752
申请日：2012-10-03
申请人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
发明人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
CPC分类号： B65D25/20 , A61J1/10 , A61J1/1462 , A61J1/201 , A61J1/2041 , A61J1/2068 , A61J1/2089 , B65B3/003 , Y10T137/9029
摘要： In one aspect, the invention is directed to a port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a retainer for connecting a first container, where the retainer is positioned in a cavity defined by a port housing that includes an axially fixed actuator. The housing also includes a plug member constructed to seal a fluid passageway between the port housing and an interior of a second container. The plug member is configured to move axially relative to the actuator. Rotation of the retainer relative to the actuator causes the plug member to move to an open position in which it does not seal a fluid passageway between the port housing and an interior of a second container. The rotation of the retainer relative to the port housing also causes the retainer to move axially relative to the port housing so that the actuator forces a stopper associated with a first container connected to the retainer into a first container.
摘要翻译： 一方面，本发明涉及一种用于在第一容器和第二容器之间建立流体连通的端口组件。 端口组件包括用于连接第一容器的保持器，其中保持器定位在由包括轴向固定的致动器的端口壳体限定的空腔中。 壳体还包括构造成密封端口壳体和第二容器内部之间的流体通道的插塞构件。 插塞构件被构造成相对于致动器轴向移动。 保持器相对于致动器的旋转使得塞构件移动到打开位置，在该打开位置中，它不密封端口壳体和第二容器内部之间的流体通道。 保持器相对于端口壳体的旋转也使得保持器相对于端口壳体轴向移动，使得致动器将与连接到保持器的第一容器相关联的止动器推入第一容器中。
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公开(公告)号：US20130102990A1
公开(公告)日：2013-04-25
申请号：US13573732
申请日：2012-10-03
IPC分类号： A61J1/20
CPC分类号： B65D25/20 , A61J1/10 , A61J1/1462 , A61J1/201 , A61J1/2041 , A61J1/2068 , A61J1/2089 , B65B3/003 , Y10T137/9029
摘要： A system for mixing the contents of a first container and a second container. The system includes the first container that has container body with an opening fluidly connected to a cavity defined by the container body, a first substance contained in the cavity, and a stopper sealing the opening. The second container includes a port assembly including a port housing connected to the second container and a retainer constructed to connect to the first container. The retainer is configured to rotate and move axially relative to the port housing, wherein relative rotation between the port housing and the retainer causes the retainer to move axially relative to the port housing. The port assembly further includes an axially fixed actuator constructed to force the stopper into the first container when the retainer is rotated relative to the port housing.
摘要翻译： 一种用于混合第一容器和第二容器的内容物的系统。 该系统包括具有容器主体的第一容器，该容器主体具有流体连接到由容器主体限定的空腔的开口，容纳在空腔中的第一物质和密封该开口的止动件。 第二容器包括端口组件，其包括连接到第二容器的端口壳体和构造成连接到第一容器的保持器。 保持器构造成相对于端口壳体旋转和轴向移动，其中端口壳体和保持器之间的相对旋转使保持器相对于端口壳体轴向移动。 端口组件还包括轴向固定的致动器，其构造成当保持器相对于端口壳体旋转时迫使止动器进入第一容器。
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公开(公告)号：US20060229562A1
公开(公告)日：2006-10-12
申请号：US11102874
申请日：2005-04-11
申请人： Ronald Marsh , Mark Follman , Edward Browka
发明人： Ronald Marsh , Mark Follman , Edward Browka
IPC分类号： A61M5/178
CPC分类号： A61M5/204 , A61M5/283 , A61M5/3155 , A61M5/31561 , A61M5/3158 , A61M5/46 , A61M2005/3128
摘要： A method and apparatus for injecting fluid into areas having high density tissue that creates a high backpressure resistance on the injection device is disclosed. The high backpressure resistance is overcome through a mechanical advantage achieved by using a secondary reservoir having a cross-sectional area smaller than the cross-sectional area of a primary reservoir. Exemplary injection device reservoir housings may comprise a primary reservoir, a secondary reservoir, a check valve, a septum penetrating cannula, travel limits, a pen needle connecting portion, sliding seal guide ribs, a sliding seal, a pen needle assembly, a needle stop, and a patient needle.
摘要翻译： 公开了一种用于将流体注入到具有高密度组织的区域中以在注射装置上产生高背压阻力的方法和装置。 通过使用具有小于主容器的横截面面积的横截面面积的次级容器实现的机械优点克服了高背压耐受性。 示例性注射装置储存器壳体可以包括主储存器，次储存器，止回阀，隔膜穿透套管，行程限制，笔针连接部分，滑动密封引导肋，滑动密封件，笔针组件，针止动件 和患者针。
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公开(公告)号：US20200008898A1
公开(公告)日：2020-01-09
申请号：US16447139
申请日：2019-06-20
申请人： Patrick ROUSCHE , Peter TEK , Charles VENTURA , Richard A. SCRIBNER , Andrew BLACK , Andrew LEOPOLD , Mark CARLSON , Todd MACY , Daniel LANE , Adam HENSEL , Edward BROWKA
发明人： Patrick ROUSCHE , Peter TEK , Charles VENTURA , Richard A. SCRIBNER , Andrew BLACK , Andrew LEOPOLD , Mark CARLSON , Todd MACY , Daniel LANE , Adam HENSEL , Edward BROWKA
摘要： Tissue access devices and methods of using the same are disclosed. The devices can have a sensor configured to occlude a flow path by deflecting a membrane into the flow path when the devices become dislodged from tissue. The sensor can be configured to partially or fully occlude the flow path. The sensor can have a spring. The spring can be biased to move the sensor from a sensor first configuration to a sensor second configuration when a force applied by the sensor first surface against a non-sensor surface changes from a first force to a second force less than the first force. The membrane can be deflected into the flow path when the sensor is in the sensor second configuration.
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公开(公告)号：US20130199643A1
公开(公告)日：2013-08-08
申请号：US13573752
申请日：2012-10-03
申请人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
发明人： John A. Domkowski , John Sundquist , Benjamin Leo Rush , David L. Foshee , Theodore J. Mosler , Edward Browka
IPC分类号： B65D25/20
CPC分类号： B65D25/20 , A61J1/10 , A61J1/1462 , A61J1/201 , A61J1/2041 , A61J1/2068 , A61J1/2089 , B65B3/003 , Y10T137/9029
摘要： In one aspect, the invention is directed to a port assembly for establishing fluid communication between a first container and a second container. The port assembly includes a retainer for connecting a first container, where the retainer is positioned in a cavity defined by a port housing that includes an axially fixed actuator. The housing also includes a plug member constructed to seal a fluid passageway between the port housing and an interior of a second container. The plug member is configured to move axially relative to the actuator. Rotation of the retainer relative to the actuator causes the plug member to move to an open position in which it does not seal a fluid passageway between the port housing and an interior of a second container. The rotation of the retainer relative to the port housing also causes the retainer to move axially relative to the port housing so that the actuator forces a stopper associated with a first container connected to the retainer into a first container.
摘要翻译： 一方面，本发明涉及一种用于在第一容器和第二容器之间建立流体连通的端口组件。 端口组件包括用于连接第一容器的保持器，其中保持器定位在由包括轴向固定的致动器的端口壳体限定的空腔中。 壳体还包括构造成密封端口壳体和第二容器内部之间的流体通道的插塞构件。 插塞构件被构造成相对于致动器轴向移动。 保持器相对于致动器的旋转使得塞构件移动到打开位置，在该打开位置中，它不密封端口壳体和第二容器内部之间的流体通道。 保持器相对于端口壳体的旋转也使得保持器相对于端口壳体轴向移动，使得致动器将与连接到保持器的第一容器相关联的止动器推入第一容器中。
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