利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

42 条记录 (耗时 0.029 秒)

    Skin treatment and drug delivery device
    1.
    发明授权
    Skin treatment and drug delivery device 有权
    皮肤治疗和药物输送装置

    公开(公告)号：US08900181B2

    公开(公告)日：2014-12-02

    申请号：US12972013

    申请日：2010-12-17

    申请人： Edward W. Knowlton

    发明人： Edward W. Knowlton

    IPC分类号： A61B17/20 ,  A61B17/32 ,  A61M35/00 ,  A61B17/322 ,  A61M5/46 ,  A61B17/00

    CPC分类号： A61M35/003 ,  A61B17/32053 ,  A61B17/32093 ,  A61B17/322 ,  A61B2017/00424 ,  A61B2017/00747 ,  A61B2017/00761 ,  A61B2017/00792 ,  A61B2017/320064 ,  A61B2017/3225 ,  A61M5/46

    摘要： A new minimally invasive surgical approach is proposed that contemplates a method and apparatus for tightening lax skin without visible scarring via a device in various surgical procedures such as plastic surgery procedures. In some embodiments, the device is a single use disposable instrument. This approach circumvents surgically related scarring and the clinical variability of electromagnetic heating of the skin and performs small multiple pixilated resections of skin as a minimally invasive alternative to large Plastic surgical resections of skin. This approach can also be employed in areas of the body that are currently off limits to plastic surgery due to the visibility of the surgical scar. In addition, the approach can perform a skin grafting operation by harvesting the transected incisions of skin from a tissue site of a donor onto a skin defect site of a recipient with reduced scarring of the patient's donor site.

    摘要翻译： 提出了一种新的微创手术方法，该方法和装置旨在通过诸如整形外科手术的各种外科手术中的装置收紧松弛的皮肤而没有可见的瘢痕形成。 在一些实施例中，该装置是单次使用的一次性器具。 这种方法规避手术相关的瘢痕形成和皮肤电磁加热的临床变异性，并进行皮肤的小型多重像素化切除，作为大面积皮肤的大面积手术切除的微创手术。 这种方法也可以用于由于手术瘢痕的可视性而目前不符合整形手术的身体的区域。 此外，该方法可以通过从供体的组织部位收集横切的皮肤切口到接受者的皮肤缺损部位，从而减少患者供体部位的瘢痕形成，从而进行皮肤移植手术。

    Method and apparatus for surgical dissection
    4.
    发明申请
    Method and apparatus for surgical dissection 审中-公开

    公开(公告)号：US20080249526A1

    公开(公告)日：2008-10-09

    申请号：US12061090

    申请日：2008-04-02

    申请人： Edward W. Knowlton

    发明人： Edward W. Knowlton

    IPC分类号： A61B18/18

    CPC分类号： A61B17/32093

    摘要： An apparatus for dissecting tissue in a substantially uniform plane of dissection includes a housing configured to be advanced under a tissue layer, and control one of a depth of dissection or tissue flap thickness. The housing thermally shields at least a portion of the tissue flap. A roller is coupled to the housing. The roller is configured to smoothly advance housing over tissue. An energy delivery device is coupled to housing. The energy delivery device is configured to be coupled to an energy source. The energy delivery device has a geometry that substantially defines a plane of dissection.

    Method and apparatus for tightening skin by controlled contraction of collagen tissue
    8.
    发明授权
    Method and apparatus for tightening skin by controlled contraction of collagen tissue 有权
    通过胶原组织受控收缩来收紧皮肤的方法和装置

    公开(公告)号：US06405090B1

    公开(公告)日：2002-06-11

    申请号：US09343943

    申请日：1999-06-30

    申请人： Edward W. Knowlton

    发明人： Edward W. Knowlton

    IPC分类号： A61F200

    CPC分类号： A61B18/1206 ,  A61B18/12 ,  A61B18/14 ,  A61B2018/00488 ,  A61B2018/0066 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0041 ,  A61M2202/064 ,  A61M2205/073 ,  A61N5/04

    摘要： A method and apparatus for tightening a surface of a skin with an underlying collagen containing tissue applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and become inflated to substantially conform a contacting exterior surface of the membrane to a skin layer. The membrane includes a cooling lumen for receiving cooling fluid. One or more thermal electrodes positioned in the membrane and transfers thermal energy to the electrolytic solution. The electrolytic solution and cooling fluid creates a reverse thermal gradient from the skin surface to the underlying collagen tissue. A thermal power source is coupled to the thermal electrodes, and a source of electrolytic solution is coupled to the membrane.

    摘要翻译： 用含有下面的含有胶原的紧固皮肤表面的方法和装置将辐射能通过皮肤施加到下面的胶原组织，而不会基本上修饰表皮中的黑素细胞和其它上皮细胞。 多孔膜适于接收电解溶液并变得充气以使膜的接触外表面基本上符合皮肤层的接触外表面。 膜包括用于接收冷却流体的冷却腔。 位于膜中的一个或多个热电极将热能转移到电解液中。 电解液和冷却液产生从皮肤表面到下面的胶原组织的反向热梯度。 热电源耦合到热电极，并且电解溶液源耦合到膜。

    Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers
    9.
    发明授权
    Method for controlled contraction of collagen in fibrous septae in subcutaneous fat layers 失效
    皮下脂肪层纤维隔膜中胶原受控收缩的方法

    公开(公告)号：US06377854B1

    公开(公告)日：2002-04-23

    申请号：US08990494

    申请日：1997-12-15

    申请人： Edward W. Knowlton

    发明人： Edward W. Knowlton

    IPC分类号： A61F200

    CPC分类号： A61B18/1206 ,  A61B18/12 ,  A61B18/14 ,  A61B2018/00488 ,  A61B2018/0066 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0041 ,  A61M2202/064 ,  A61M2205/073 ,  A61N5/04

    摘要： A method and apparatus applies radiant energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A membrane is adapted to receive an electrolytic solution and become inflated to substantially conform a contacting exterior surface of the membrane to a skin layer. The membrane includes a cooling lumen for receiving cooling fluid. One or more thermal electrodes positioned in the membrane and transfers thermal energy to the electrolytic solution. The electrolytic solution and cooling fluid creates a reverse thermal gradient from the skin surface to the underlying collagen tissue. A thermal power source is coupled to the thermal electrodes, and a source of electrolytic solution is coupled to the membrane.

    摘要翻译： 一种方法和装置将辐射能通过皮肤施加到下面的胶原组织，而不会基本上修饰表皮中的黑素细胞和其它上皮细胞。 膜适于接收电解溶液并变得充气以使膜的接触外表面基本上符合皮肤层的接触外表面。 膜包括用于接收冷却流体的冷却腔。 位于膜中的一个或多个热电极将热能转移到电解液中。 电解液和冷却液产生从皮肤表面到下面的胶原组织的反向热梯度。 热电源耦合到热电极，并且电解溶液源耦合到膜。

    Method for controlled contraction of collagen tissue using RF energy
    10.
    发明授权
    Method for controlled contraction of collagen tissue using RF energy 失效
    使用RF能量控制收缩胶原组织的方法

    公开(公告)号：US5919219A

    公开(公告)日：1999-07-06

    申请号：US914681

    申请日：1997-08-19

    申请人： Edward W. Knowlton

    发明人： Edward W. Knowlton

    IPC分类号： A61B18/12 ,  A61B18/14 ,  A61M15/00 ,  A61N5/04 ,  A61F2/00

    CPC分类号： A61B18/1206 ,  A61B18/12 ,  A61B18/14 ,  A61M15/0028 ,  A61M15/0036 ,  A61M15/0041 ,  A61N5/04 ,  A61B2018/0066 ,  A61M2202/064 ,  A61M2205/073

    摘要： A method for tightening a surface of a skin with an underlying collagen containing tissue applies RF energy through the skin to underlying collagen tissue without substantially modifying melanocytes and other epithelial cells in the epidermis. A porous membrane is adapted to receive an electrolytic solution and become inflated to substantially conform a contacting exterior surface of the membrane to a skin layer. The membrane includes a cooling lumen for receiving cooling fluid. One or more thermal electrodes positioned in the membrane and transfers thermal energy to the electrolytic solution. The electrolytic solution and cooling fluid creates a reverse thermal gradient from the skin surface to the underlying collagen tissue. A thermal power source is coupled to the thermal electrodes, and a source of electrolytic solution is coupled to the membrane.

    摘要翻译： 用含有下面的含有胶原的紧固皮肤表面的方法将RF能量通过皮肤施加到下面的胶原组织，而不会基本上修饰表皮中的黑素细胞和其它上皮细胞。 多孔膜适于接收电解溶液并变得充气以使膜的接触外表面基本上符合皮肤层的接触外表面。 膜包括用于接收冷却流体的冷却腔。 位于膜中的一个或多个热电极将热能转移到电解液中。 电解液和冷却液产生从皮肤表面到下面的胶原组织的反向热梯度。 热电源耦合到热电极，并且电解溶液源耦合到膜。