公开(公告)号：US20210321503A1

公开(公告)日：2021-10-14

申请号：US17218327

申请日：2021-03-31

申请人： Mary Ellen Brown

发明人： Mary Ellen Brown

IPC分类号： H05B47/115 ,  H05B47/19 ,  F21L4/08 ,  F21S4/22 ,  F21V33/00

摘要： This present invention relates to an illuminated source of light used for illuminating specific areas, such as door handles, door locks, door knobs and more. The source of light comprises an integrated light source, such as a plurality of LED lights, that can be turned ON manually or automatically based on motion detection of an approaching individual or object. Additionally, the source of light may be automatically turned OFF after a predetermined duration of time has elapsed in order to conserve battery life. The illuminated source of light offers a functional and decorative lighting solution for illuminating dark or dimly lit areas, such as dwelling entries.

公开(公告)号：US08790006B2

公开(公告)日：2014-07-29

申请号：US12627293

申请日：2009-11-30

申请人： Hejie Li ,  Samhita Dasgupta ,  Edward Randall Furlong ,  Nirm Velumylum Nirmalan ,  Anquan Wang ,  Guanghua Wang ,  Stephen Thomas Walls ,  Lesley Ellen Brown

发明人： Hejie Li ,  Rodrick Gordon Brown ,  Samhita Dasgupta ,  Edward Randall Furlong ,  Nirm Velumylum Nirmalan ,  Anquan Wang ,  Guanghua Wang ,  Stephen Thomas Walls

IPC分类号： G01J5/00 ,  G01K1/14 ,  G01K11/00

CPC分类号： G01J5/0014 ,  G01J3/02 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/28 ,  G01J3/36 ,  G01J3/42 ,  G01J3/443 ,  G01J5/0022 ,  G01J5/0044 ,  G01J5/0088 ,  G01J5/08 ,  G01J5/0815 ,  G01J5/0821 ,  G01J5/0846 ,  G01J5/0862 ,  G01J5/58

摘要： A thermal measurement system that includes a light collection device and a detection system in communication with the device. The detection system includes two detection subsystems, wherein one subsystem is configured to detect light from a surface of an object, while the other subsystem is configured to detect light from the surface and a gas. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

摘要翻译： 一种热测量系统，其包括光收集装置和与装置通信的检测系统。 检测系统包括两个检测子系统，其中一个子系统被配置为检测来自物体表面的光，而另一子系统被配置为检测来自表面的气体和气体。 已经根据具体实施例描述了本发明，并且认识到除了明确说明的那些之外的等同物，替代方案和修改是可能的并且在所附权利要求的范围内。

公开(公告)号：US20090227559A1

公开(公告)日：2009-09-10

申请号：US12067858

申请日：2006-10-03

申请人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

发明人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

IPC分类号： A61K31/397 ,  C12Q1/68

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the apoB gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

摘要翻译： 本发明涉及向某些合适的患者施用药学上可用的抗凝药物的方法和鉴定那些适合接受药物的患者的方法。 特别地，本发明包括鉴定apoB基因中的某些SNP与施用西咪加群之后丙氨酸氨基转移酶（ALAT）水平升高的易感性之间的关联。 因此，本发明涉及用于预测西替加联给药后升高的ALAT的易感性的方法以及向某些合适的患者施用药学上可用的抗凝药物的方法。

公开(公告)号：US20110128989A1

公开(公告)日：2011-06-02

申请号：US12627293

申请日：2009-11-30

申请人： Hejie Li ,  Roderick Gordon Brown ,  Samhita Dasgupta ,  Edward Randall Furlong ,  Nirm Velumylum Nirmalan ,  Anquan Wang ,  Guanghua Wang ,  Stephen Thomas Walls ,  Lesley Ellen Brown

发明人： Hejie Li ,  Roderick Gordon Brown ,  Samhita Dasgupta ,  Edward Randall Furlong ,  Nirm Velumylum Nirmalan ,  Anquan Wang ,  Guanghua Wang ,  Stephen Thomas Walls ,  Lesley Ellen Brown

IPC分类号： G01J5/00

CPC分类号： G01J5/0014 ,  G01J3/02 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/28 ,  G01J3/36 ,  G01J3/42 ,  G01J3/443 ,  G01J5/0022 ,  G01J5/0044 ,  G01J5/0088 ,  G01J5/08 ,  G01J5/0815 ,  G01J5/0821 ,  G01J5/0846 ,  G01J5/0862 ,  G01J5/58

摘要： A thermal measurement system that includes a light collection device and a detection system in communication with the device. The detection system includes two detection subsystems, wherein one subsystem is configured to detect light from a surface of an object, while the other subsystem is configured to detect light from the surface and a gas. The present invention has been described in terms of specific embodiment(s), and it is recognized that equivalents, alternatives, and modifications, aside from those expressly stated, are possible and within the scope of the appending claims.

摘要翻译： 一种热测量系统，其包括光收集装置和与装置通信的检测系统。 检测系统包括两个检测子系统，其中一个子系统被配置为检测来自物体表面的光，而另一子系统被配置为检测来自表面的气体和气体。 已经根据具体实施例描述了本发明，并且认识到除了明确说明的那些之外的等同物，替代方案和修改是可能的并且在附加权利要求的范围内。

公开(公告)号：US20090029367A1

公开(公告)日：2009-01-29

申请号：US12067864

申请日：2006-10-03

申请人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

发明人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6883 ,  A61K38/07 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the PON1 gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran or tacrine administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran or tacrine administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

摘要翻译： 本发明涉及向某些合适的患者施用药学上可用的抗凝药物的方法和鉴定那些适合接受药物的患者的方法。 特别地，本发明围绕在PON1基因中的某些SNP之间的关联的识别以及在施用西他加他汀或他克林给药后对丙氨酸氨基转移酶（ALAT）水平升高的敏感性。 因此，本发明涉及用于预测西咪加群或他克林给药后升高的ALAT的易感性的方法以及向某些合适的患者施用药学上可用的抗凝药物的方法。

公开(公告)号：US11363698B2

公开(公告)日：2022-06-14

申请号：US17218327

申请日：2021-03-31

申请人： Mary Ellen Brown

发明人： Mary Ellen Brown

IPC分类号： H05B47/115 ,  H05B47/19 ,  F21L4/08 ,  F21V33/00 ,  F21S4/22 ,  H05B47/17 ,  F21Y115/10

摘要： This present invention relates to an illuminated source of light used for illuminating specific areas, such as door handles, door locks, door knobs and more. The source of light comprises an integrated light source, such as a plurality of LED lights, that can be turned ON manually or automatically based on motion detection of an approaching individual or object. Additionally, the source of light may be automatically turned OFF after a predetermined duration of time has elapsed in order to conserve battery life. The illuminated source of light offers a functional and decorative lighting solution for illuminating dark or dimly lit areas, such as dwelling entries.

公开(公告)号：US20090054394A1

公开(公告)日：2009-02-26

申请号：US12067863

申请日：2006-10-03

申请人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

发明人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

IPC分类号： C12Q1/68 ,  A61K31/397 ,  A61P9/00

CPC分类号： C12Q1/6883 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between certain SNPs in the MGST3 gene and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

摘要翻译： 本发明涉及向某些合适的患者施用药学上可用的抗凝药物的方法和鉴定那些适合接受药物的患者的方法。 特别地，本发明包括鉴定MGST3基因中某些SNP之间的关联以及施用西咪加群后对丙氨酸氨基转移酶（ALAT）的增加水平的敏感性。 因此，本发明涉及用于预测西替加联给药后升高的ALAT的易感性的方法以及向某些合适的患者施用药学上可用的抗凝药物的方法。

公开(公告)号：US20090036424A1

公开(公告)日：2009-02-05

申请号：US12067867

申请日：2006-10-03

申请人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

发明人： Olof Bengtsson ,  Ellen Brown ,  Stefan Carlsson ,  Neil James Gibson ,  Ansar Jawaid ,  Andreas Kindmark ,  Ruth Eleanor March

IPC分类号： A61K31/397 ,  C12Q1/68

CPC分类号： C12Q1/6881 ,  C12Q2600/106 ,  C12Q2600/156 ,  C12Q2600/172

摘要： This invention relates to a method for administering a pharmaceutically useful anticoagulant drug to certain suitable patients and a method for identifying those patients suitable for receiving the drug. In particular, the invention surrounds the identification of an association between HLA-DRB1*07 allele and susceptibility to increased levels of alanine aminotransferase (ALAT) following ximelagatran administration. Thus, this invention relates to methods for predicting susceptibility to elevated ALAT following ximelagatran administration and to methods for administering a pharmaceutically useful anticoagulant drug to certain suitable patients.

摘要翻译： 本发明涉及向某些合适的患者施用药学上可用的抗凝药物的方法和鉴定那些适合接受药物的患者的方法。 特别地，本发明包括确定HLA-DRB1 * 07等位基因与施用西咪加群后丙氨酸转氨酶（ALAT）水平升高的易感性之间的关联。 因此，本发明涉及用于预测西替加联给药后升高的ALAT的易感性的方法以及向某些合适的患者施用药学上可用的抗凝药物的方法。