-
公开(公告)号:US5830754A
公开(公告)日:1998-11-03
申请号:US361014
申请日:1994-12-21
申请人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
发明人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
CPC分类号: C07K14/70507 , C07K16/2806 , A61K38/00
摘要: A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.
-
公开(公告)号:US5550055A
公开(公告)日:1996-08-27
申请号:US449199
申请日:1995-05-24
申请人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
发明人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
CPC分类号: C07K16/2806 , C07K14/70507 , A61K38/00
摘要: A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.
摘要翻译: 编码能够抑制T淋巴细胞活化的人T11或其片段的cDNA序列。
-
公开(公告)号:US07247438B1
公开(公告)日:2007-07-24
申请号:US08948124
申请日:1997-10-09
IPC分类号: G01N33/53
CPC分类号: C12N9/6475 , A61K38/00
摘要: Methods for identifying agents which enhance the activity of a caspase according to the invention are described, as well as methods for enhancing caspase activity and methods for enhancing apoptosis in a lymphocyte.
摘要翻译: 本发明描述了提高半胱天冬酶活性的试剂的方法,以及增强半胱天冬酶活性的方法和增强淋巴细胞凋亡的方法。
-
公开(公告)号:US20050084916A1
公开(公告)日:2005-04-21
申请号:US10783994
申请日:2004-02-20
申请人: Ellis Reinherz , Linda Clayton , Emma Fiorini , Pedro Reche , Ingo Schmitz
发明人: Ellis Reinherz , Linda Clayton , Emma Fiorini , Pedro Reche , Ingo Schmitz
IPC分类号: C07H21/04 , C07K14/47 , C12N9/64 , G01N33/574
CPC分类号: C07K14/4702
摘要: The identification of a novel gene, termed IκBNS, regulated during negative selection of immature CD4+CD8+double positive (DP) thymocytes in mice, and the human homolog of the gene, are described, along with the gene products produced by these genes. Methods of using the disclosed genes and gene products are also described.
摘要翻译: 在小鼠中对未成熟的CD4 + CD8 + + / - 双阳性(DP)胸腺细胞的阴性选择调节的称为IkappaBNS的新基因的鉴定以及该基因的人类同源物 ,以及这些基因产生的基因产物。 还描述了使用所公开的基因和基因产物的方法。
-
公开(公告)号:US20050015232A1
公开(公告)日:2005-01-20
申请号:US10486278
申请日:2002-08-08
申请人: Ellis Reinherz , Mikyung Kim , Pedro Reche , Jiahuai Wang
发明人: Ellis Reinherz , Mikyung Kim , Pedro Reche , Jiahuai Wang
IPC分类号: C07K14/155 , C07K14/16 , C07K14/315 , C07K14/395 , C07K14/445 , G06F19/16 , G06F19/18 , G06G7/48 , G06G7/58
CPC分类号: C07K14/395 , C07K14/005 , C07K14/315 , C07K2299/00 , C07K2319/20 , C07K2319/73 , C12N2740/15022 , C12N2740/16122 , G06F19/16 , G06F19/18
摘要: The invention features a method of generating an immunogenic compound with the ability to induce an immune response to a molecule produced by a pathogenic agent, e.g., a infectious agent or a tumor cell. Also included in the invention are an immunogenic compound generated by the method of the invention and a method of inducing an immune response in a mammal that involves administering the immunogenic compound to the mammal.
摘要翻译: 本发明的特征在于产生具有诱导对由病原体(例如感染剂或肿瘤细胞)产生的分子的免疫应答能力的免疫原性化合物的方法。 本发明还包括通过本发明的方法产生的免疫原性化合物和在哺乳动物中诱导免疫应答的方法,其涉及向哺乳动物施用免疫原性化合物。
-
公开(公告)号:US5608037A
公开(公告)日:1997-03-04
申请号:US443847
申请日:1995-05-18
申请人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
发明人: Ellis Reinherz , Peter Sayre , Hsiu-Ching Chang , Neil Richardson
IPC分类号: A61K38/00 , C07K14/705 , C07K16/28 , C12N15/00 , C07K14/00
CPC分类号: C07K16/2806 , C07K14/70507 , A61K38/00
摘要: A cDNA sequence encoding human T11 or a fragment thereof which is capable of inhibiting T-lymphocyte activation.
摘要翻译: 编码能够抑制T淋巴细胞活化的人T11或其片段的cDNA序列。
-
-
-
-
-