公开(公告)号：US4854322A

公开(公告)日：1989-08-08

申请号：US98400

申请日：1987-09-18

Applicant: Stephen R. Ash ,  Elsa M. Janle-Swain

Inventor： Stephen R. Ash ,  Elsa M. Janle-Swain

IPC: A61B5/00 ,  A61B10/00 ,  B01D61/18 ,  B01D63/02 ,  G01N33/483 ,  G01N33/487

CPC classification number: A61B5/14865 ,  A61B5/14528 ,  A61B5/14542 ,  A61B5/1473 ,  A61B5/686 ,  B01D61/18 ,  B01D63/024 ,  A61B2010/008 ,  B01D2313/06

Abstract: A method and device for long term monitoring of the blood level of various blood constituents. The monitoring is accomplished by capillary filtration and collection of an ultrafiltrate of blood. Filtration of the ultrafiltrate occurs through a filter composed of hollow fibers which are implanted within an interstitial body space in fluid communication with blood capillaries. The ultrafiltrate is drawn through the filter and into an ultrafiltrate collector which extends externally of the body. The collector provides a vacuum for withdrawing the ultrafiltrate and holds discrete liquid samples of the ultrafiltrate. The method and device is particularly suited for long term monitoring of blood glucose levels in diabetic patients or other blood chemical constituents in other patients.

Abstract translation: 一种用于长期监测各种血液成分血液水平的方法和装置。 通过毛细管过滤和血液超滤液的收集来实现监测。 超滤液的过滤通过由中空纤维构成的过滤器发生，所述过滤器植入在与毛细管流体连通的间隙体空间内。 超滤液通过过滤器吸入超滤体收集器，该收集器从身体外部延伸出来。 收集器提供用于抽出超滤液的真空并保持超滤液的离散液体样品。 该方法和装置特别适用于长期监测糖尿病患者或其他患者其他血液化学成分中的血糖水平。

公开(公告)号：US4777953A

公开(公告)日：1988-10-18

申请号：US18616

申请日：1987-02-25

Applicant: Stephen R. Ash ,  Elsa M. Janle-Swain

Inventor： Stephen R. Ash ,  Elsa M. Janle-Swain

IPC: G01N1/10 ,  A61B5/00 ,  A61B5/145 ,  A61B10/00 ,  B01D61/18 ,  B01D63/02 ,  G01N33/483 ,  G01N33/487 ,  A61B5/05

CPC classification number: B01D63/024 ,  A61B5/14528 ,  A61B5/14542 ,  A61B5/14865 ,  A61B5/415 ,  A61B5/686 ,  B01D61/18 ,  A61B2010/008 ,  B01D2313/06

Abstract: A method and device for long term monitoring of the blood level of various blood constituents. The monitoring is accomplished by capillary filtration and collection of an ultrafiltrate of blood. Filtration of the ultrafiltrate occurs through a filter composed of hollow fibers which are implanted within an interstitial body space in fluid communication with blood capillaries. The ultrafiltrate is drawn through the filter and into an ultrafiltrate collector which extends externally of the body. The collector provides a vacuum for withdrawing the ultrafiltrate and holds discrete liquid samples of the ultrafiltrate. The method and device is particularly suited for long term monitoring of blood glucose levels in diabetic patients or other blood chemical constituents in other patients.

Abstract translation: 一种用于长期监测各种血液成分血液水平的方法和装置。 通过毛细管过滤和血液超滤液的收集来实现监测。 超滤液的过滤通过由中空纤维构成的过滤器发生，所述过滤器植入在与毛细管流体连通的间隙体空间内。 超滤液通过过滤器吸入超滤体收集器，该收集器从身体外部延伸出来。 收集器提供用于抽出超滤液的真空并保持超滤液的离散液体样品。 该方法和装置特别适用于长期监测糖尿病患者或其他患者其他血液化学成分中的血糖水平。