公开(公告)号：US20130158638A1

公开(公告)日：2013-06-20

申请号：US13608914

申请日：2012-09-10

申请人： Enri Zhulati ,  Thomas Wright

发明人： Enri Zhulati ,  Thomas Wright

IPC分类号： A61N1/05 ,  H01B13/00

CPC分类号： A61N1/0553 ,  A61N1/05 ,  A61N1/0551 ,  H01B13/00 ,  Y10T29/49117

摘要： In one embodiment, an implantable stimulation lead for delivering electrical stimulation to tissue of a patient, the implantable stimulation lead comprises: a lead body comprising a plurality of wires strands that form a solid helical hollow tube that is maintained by mutual contact pressure of neighboring wire strands, wherein the plurality of wire strands comprise an outer coating of non-conductive material to electrically isolate each of the plurality of wire strands from each other; and a plurality of electrodes with each electrode being electrically coupled to one of the plurality of wire strands.

摘要翻译： 在一个实施例中，可植入刺激引线用于向患者的组织递送电刺激，所述可植入刺激引线包括：引线主体，其包括多个线束，所述引线主体形成固体螺旋形中空管，其通过相邻线的相互接触压力 线，其中所述多根线股包括非导电材料的外涂层，以将所述多个线束中的每一个彼此电隔离; 以及多个电极，其中每个电极电耦合到多个线股中的一个。

公开(公告)号：US20150290461A1

公开(公告)日：2015-10-15

申请号：US14252546

申请日：2014-04-14

申请人： Xiaoyi Min ,  Timothy A. Fayram ,  Brad Maruca ,  Enri Zhulati ,  Kyle Pulley

发明人： Xiaoyi Min ,  Timothy A. Fayram ,  Brad Maruca ,  Enri Zhulati ,  Kyle Pulley

IPC分类号： A61N1/36 ,  A61N1/08 ,  A61N1/05 ,  A61N1/372

CPC分类号： A61N1/36135 ,  A61B5/407 ,  A61B5/4836 ,  A61N1/0553 ,  A61N1/08 ,  A61N1/36185 ,  A61N1/37235 ,  A61N1/37247

摘要： The present disclosure provides systems and methods for neurostimulation. The method includes applying electrical stimulation to a patient using a paddle lead that includes a plurality of electrodes, acquiring evoked response data using at least some of the plurality of electrodes, wherein the evoked response data is indicative of a patient response to the electrical stimulation, transmitting the evoked response data to a computing device, and processing the evoked response data using the computing device to facilitate monitoring the applied electrical stimulation.

摘要翻译： 本公开提供了用于神经刺激的系统和方法。 该方法包括使用包括多个电极的桨导线向患者施加电刺激，使用多个电极中的至少一些来获取诱发的反应数据，其中所述诱发的反应数据指示患者对电刺激的反应， 将所述诱发响应数据发送到计算设备，以及使用所述计算设备处理所述诱发的响应数据，以便于监视所施加的电刺激。

公开(公告)号：US08544170B2

公开(公告)日：2013-10-01

申请号：US13242234

申请日：2011-09-23

申请人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

发明人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

IPC分类号： H01R43/00 ,  H05K13/00

CPC分类号： A61N1/05 ,  A61N1/086 ,  Y10T29/4902 ,  Y10T29/49117 ,  Y10T29/49128 ,  Y10T29/49155 ,  Y10T29/49169

摘要： In one embodiment, a percutaneous stimulation lead for applying electrically stimulation pulses to tissue of the patient comprises: a plurality of electrode assemblies electrically coupled to a plurality of terminals through a plurality of conductors of the stimulation lead, wherein each electrode assembly is disposed in an annular manner around the lead body and each electrode assembly comprises (i) an electrode adapted to deliver electrical stimulation to tissue of a patient, (ii) an interior conductive layer, and (iii) a dielectric layer disposed between the electrode and the interior conductive layer; the electrode and interior conductive layer being capacitively coupled, the dielectric layer further comprising an inductor, the inductor being electrically connected to one of the plurality of conductors through the interior conductive layer, and the inductor being electrically coupled to the electrode.

摘要翻译： 在一个实施例中，用于向患者的组织施加电刺激脉冲的经皮刺激引线包括：通过刺激引线的多个导体电耦合到多个端子的多个电极组件，其中每个电极组件设置在 环形方式围绕引线体，并且每个电极组件包括（i）适于将电刺激递送到患者组织的电极，（ii）内部导电层，和（iii）设置在电极和内部导电之间的电介质层 层; 所述电极和内部导电层电容耦合，所述介电层还包括电感器，所述电感器通过所述内部导电层电连接到所述多个导体中的一个，并且所述电感器电耦合到所述电极。

公开(公告)号：US08532788B2

公开(公告)日：2013-09-10

申请号：US13549736

申请日：2012-07-16

申请人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

发明人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

IPC分类号： A61N1/00

CPC分类号： A61N1/0488 ,  A61N1/3605

摘要： In one embodiment, a neurostimulation lead comprises an elongated body of insulative material, comprising a first end portion and a second end portion; a plurality of terminals longitudinally positioned along the first end portion; a plurality of electrodes longitudinally positioned along the second end portion; a plurality of conductors electrically coupling the plurality of electrodes to the plurality of terminals; a flexible metal longitudinal stiffener positioned within the elongated body wherein the stiffener has a plurality of longitudinal zones and each zone has a different column strength, the column strength of one or more zones of the plurality of longitudinal zones being defined by cuts or gaps in the stiffener, the stiffener causing the neurostimulation lead to exhibit a greatest amount of column strength adjacent to one end portion of the elongated body and to transition to a lower column strength toward a medial portion of the elongated body.

摘要翻译： 在一个实施例中，神经刺激引线包括细长的绝缘材料体，包括第一端部部分和第二端部部分; 沿所述第一端部纵向定位的多个端子; 沿所述第二端部纵向定位的多个电极; 将多个电极电耦合到多个端子的多个导体; 位于所述细长体内的柔性金属纵向加强筋，其中所述加强件具有多个纵向区域，并且每个区域具有不同的柱强度，所述多个纵向区域中的一个或多个区域的柱强度由所述多个纵向区域中的切口或间隙限定 加强件，引起神经刺激的加强件导致邻近细长主体的一个端部部分显示出最大量的柱强度，并朝着细长体的中间部分转变到较低的柱强度。

公开(公告)号：US20120279063A1

公开(公告)日：2012-11-08

申请号：US13549736

申请日：2012-07-16

申请人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

发明人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

IPC分类号： H01R43/16

CPC分类号： A61N1/0488 ,  A61N1/3605

摘要： In one embodiment, a neurostimulation lead comprises an elongated body of insulative material, comprising a first end portion and a second end portion; a plurality of terminals longitudinally positioned along the first end portion; a plurality of electrodes longitudinally positioned along the second end portion; a plurality of conductors electrically coupling the plurality of electrodes to the plurality of terminals; a flexible metal longitudinal stiffener positioned within the elongated body wherein the stiffener has a plurality of longitudinal zones and each zone has a different column strength, the column strength of one or more zones of the plurality of longitudinal zones being defined by cuts or gaps in the stiffener, the stiffener causing the neurostimulation lead to exhibit a greatest amount of column strength adjacent to one end portion of the elongated body and to transition to a lower column strength toward a medial portion of the elongated body.

摘要翻译： 在一个实施例中，神经刺激引线包括细长的绝缘材料体，包括第一端部部分和第二端部部分; 沿所述第一端部纵向定位的多个端子; 沿所述第二端部纵向定位的多个电极; 将多个电极电耦合到多个端子的多个导体; 位于所述细长体内的柔性金属纵向加强筋，其中所述加强件具有多个纵向区域，并且每个区域具有不同的柱强度，所述多个纵向区域中的一个或多个区域的柱强度由所述多个纵向区域中的切口或间隙限定 加强件，引起神经刺激的加强件导致邻近细长主体的一个端部部分显示出最大量的柱强度，并朝着细长体的中间部分转变到较低的柱强度。

公开(公告)号：US08244372B1

公开(公告)日：2012-08-14

申请号：US12416813

申请日：2009-04-01

申请人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

发明人： Enri Zhulati ,  Terry D. Daglow ,  Brian Franz ,  Sojan Abraham

IPC分类号： A61N1/00 ,  A61B5/01

CPC分类号： A61N1/0488 ,  A61N1/3605

摘要： In one embodiment, a neurostimulation lead comprises an elongated body of insulative material, comprising a first end portion and a second end portion; a plurality of terminals longitudinally positioned along the first end portion; a plurality of electrodes longitudinally positioned along the second end portion; a plurality of conductors electrically coupling the plurality of electrodes to the plurality of terminals; a flexible metal longitudinal stiffener positioned within the elongated body wherein the stiffener has a plurality of longitudinal zones and each zone has a different column strength, the column strength of one or more zones of the plurality of longitudinal zones being defined by cuts or gaps in the stiffener, the stiffener causing the neurostimulation lead to exhibit a greatest amount of column strength adjacent to one end portion of the elongated body and to transition to a lower column strength toward a medial portion of the elongated body.

摘要翻译： 在一个实施例中，神经刺激引线包括细长的绝缘材料体，包括第一端部部分和第二端部部分; 沿所述第一端部纵向定位的多个端子; 沿所述第二端部纵向定位的多个电极; 将多个电极电耦合到多个端子的多个导体; 位于所述细长体内的柔性金属纵向加强筋，其中所述加强件具有多个纵向区域，并且每个区域具有不同的柱强度，所述多个纵向区域中的一个或多个区域的柱强度由所述多个纵向区域中的切口或间隙限定 加强件，引起神经刺激的加强件导致邻近细长主体的一个端部部分显示出最大量的柱强度，并朝着细长体的中间部分转变到较低的柱强度。

公开(公告)号：US20120011711A1

公开(公告)日：2012-01-19

申请号：US13242234

申请日：2011-09-23

申请人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

发明人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

IPC分类号： H01R43/00

CPC分类号： A61N1/05 ,  A61N1/086 ,  Y10T29/4902 ,  Y10T29/49117 ,  Y10T29/49128 ,  Y10T29/49155 ,  Y10T29/49169

摘要： In one embodiment, a percutaneous stimulation lead for applying electrically stimulation pulses to tissue of the patient comprises: a plurality of electrode assemblies electrically coupled to a plurality of terminals through a plurality of conductors of the stimulation lead, wherein each electrode assembly is disposed in an annular manner around the lead body and each electrode assembly comprises (i) an electrode adapted to deliver electrical stimulation to tissue of a patient, (ii) an interior conductive layer, and (iii) a dielectric layer disposed between the electrode and the interior conductive layer; the electrode and interior conductive layer being capacitively coupled, the dielectric layer further comprising an inductor, the inductor being electrically connected to one of the plurality of conductors through the interior conductive layer, and the inductor being electrically coupled to the electrode.

摘要翻译： 在一个实施例中，用于向患者的组织施加电刺激脉冲的经皮刺激引线包括：通过刺激引线的多个导体电耦合到多个端子的多个电极组件，其中每个电极组件设置在 环形方式围绕引线体，并且每个电极组件包括（i）适于将电刺激递送到患者组织的电极，（ii）内部导电层，和（iii）设置在电极和内部导电之间的电介质层 层; 所述电极和内部导电层电容耦合，所述介电层还包括电感器，所述电感器通过所述内部导电层电连接到所述多个导体中的一个，并且所述电感器电耦合到所述电极。

公开(公告)号：US08032230B1

公开(公告)日：2011-10-04

申请号：US12248409

申请日：2008-10-09

申请人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

发明人： Timothy J. Cox ,  John Erickson ,  Enri Zhulati ,  Terry Daglow ,  John Swanson

IPC分类号： A61N1/00

CPC分类号： A61N1/05 ,  A61N1/086 ,  Y10T29/4902 ,  Y10T29/49117 ,  Y10T29/49128 ,  Y10T29/49155 ,  Y10T29/49169

摘要： In one embodiment, a percutaneous stimulation lead for applying electrically stimulation pulses to tissue of the patient comprises: a plurality of electrode assemblies electrically coupled to a plurality of terminals through a plurality of conductors of the stimulation lead, wherein each electrode assembly is disposed in an annular manner around the lead body and each electrode assembly comprises (i) an electrode adapted to deliver electrical stimulation to tissue of a patient, (ii) an interior conductive layer, and (iii) a dielectric layer disposed between the electrode and the interior conductive layer; the electrode and interior conductive layer being capacitively coupled, the dielectric layer further comprising an inductor, the inductor being electrically connected to one of the plurality of conductors through the interior conductive layer, and the inductor being electrically coupled to the electrode.

摘要翻译： 在一个实施例中，用于向患者的组织施加电刺激脉冲的经皮刺激引线包括：通过刺激引线的多个导体电耦合到多个端子的多个电极组件，其中每个电极组件设置在 环形方式围绕引线体，并且每个电极组件包括（i）适于将电刺激递送到患者组织的电极，（ii）内部导电层，和（iii）设置在电极和内部导电之间的电介质层 层; 所述电极和内部导电层电容耦合，所述介电层还包括电感器，所述电感器通过所述内部导电层电连接到所述多个导体中的一个，并且所述电感器电耦合到所述电极。