公开(公告)号：US4980462A

公开(公告)日：1990-12-25

申请号：US368188

申请日：1989-06-19

申请人： Karl-Anders Karlsson ,  Erling Norrby ,  Goran Wadell

发明人： Karl-Anders Karlsson ,  Erling Norrby ,  Goran Wadell

IPC分类号： A61K31/70 ,  A61K31/7028 ,  A61K39/12 ,  C07H3/06 ,  C07H15/04 ,  C07H15/10 ,  C12N7/02 ,  C12Q1/70 ,  G01N33/566 ,  G01N33/569

CPC分类号： C07H15/04 ,  C07H3/06 ,  C12N7/00 ,  C12Q1/70 ,  G01N33/566 ,  G01N33/56983 ,  C12N2760/18851

摘要： A second-step virus binding receptor is found in nature on the surface of animal and plant cells. This receptor is thought to be needed for virus penetration into target cells. The second-step receptor has been found to bind a wide variety of viruses belonging to a number of different families. The second-step receptor and natural or synthetic substances which correspond to or are analogous to the binding epitope of the second-step receptor in that they are able to bind to a site on the virus which recognizes the binding epitope of the natural second-step receptor, are therefore indicated for the diagnosis, prophylaxis or treatment of viral infections.

公开(公告)号：US4859769A

公开(公告)日：1989-08-22

申请号：US916542

申请日：1986-11-05

申请人： Karl-Anders Karlsson ,  Erling Norrby ,  Goran Wadell

发明人： Karl-Anders Karlsson ,  Erling Norrby ,  Goran Wadell

IPC分类号： A61K31/70 ,  A61K31/7028 ,  A61K39/12 ,  C07H3/06 ,  C07H15/04 ,  C07H15/10 ,  C12N7/02 ,  C12Q1/70 ,  G01N33/566 ,  G01N33/569

CPC分类号： C07H15/04 ,  C07H3/06 ,  C12N7/00 ,  C12Q1/70 ,  G01N33/566 ,  G01N33/56983 ,  C12N2760/18851

摘要： A second-step virus binding receptor is found in nature on the surface of animal and plant cells. This receptor is thought to be needed for virus penetration into target cells. The second-step receptor has been found to bind a wide variety of viruses belonging to a number of different families. The second-step receptor and natural or synthetic substances which correspond to or are analogous to the binding epitope of the second-step receptor in that they are able to bind to a site on the virus which recognizes the binding epitope of the natural second-step receptor, are therefore indicated for the diagnosis, prophylaxis or treatment of viral infections.

摘要翻译： PCT No.PCT / DK86 / 00007 Sec。 371日期：1986年11月5日 102（e）日期1986年11月5日PCT申请日1986年1月13日PCT公布。 出版物WO86 / 03971 日期1986年7月17日。在动物和植物细胞表面上发现自然界中的第二步病毒结合受体。 认为该受体是病毒渗入靶细胞所必需的。 已经发现第二步受体结合属于多个不同家族的各种病毒。 第二步受体和天然或合成物质对应于或类似于第二步受体的结合表位，因为它们能够结合识别天然第二步的结合表位的病毒位点 受体，因此被指示用于诊断，预防或治疗病毒感染。