公开(公告)号：US4608200A

公开(公告)日：1986-08-26

申请号：US676379

申请日：1984-11-30

申请人： Pyare L. Khanna ,  Evan S. Snyder ,  Prithipal Singh

发明人： Pyare L. Khanna ,  Evan S. Snyder ,  Prithipal Singh

IPC分类号： G01N33/94 ,  A61K31/04 ,  A61K39/00 ,  C07C79/46 ,  G01N33/531

CPC分类号： G01N33/9446 ,  Y10S436/822 ,  Y10S436/823 ,  Y10S530/807

摘要： Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxo-carbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

摘要翻译： 提供氯霉素衍生物用于制备用于产生专门用于氯霉素的抗体的抗原缀合物。 具体地，芳基氨基被衍生化以引入用于与抗原形成酰胺的非羰基。 然后将缀合物注射到脊椎动物中以产生以常规方式分离的抗血清，并在竞争性蛋白质结合测定中发现特别的用途。

公开(公告)号：US4608252A

公开(公告)日：1986-08-26

申请号：US781075

申请日：1985-09-27

申请人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

发明人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

IPC分类号： G01N33/94 ,  A61K39/00

CPC分类号： G01N33/9446 ,  Y10S435/961

摘要： Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxo-carbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

摘要翻译： 提供氯霉素衍生物用于制备用于产生专门用于氯霉素的抗体的抗原缀合物。 具体地，芳基氨基被衍生化以引入用于与抗原形成酰胺的非羰基。 然后将缀合物注射到脊椎动物中以产生以常规方式分离的抗血清，并在竞争性蛋白质结合测定中发现特别的用途。

公开(公告)号：US4544765A

公开(公告)日：1985-10-01

申请号：US676689

申请日：1984-11-30

申请人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

发明人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

IPC分类号： G01N33/94 ,  C07C87/64 ,  C07C101/44

CPC分类号： G01N33/9446

摘要： Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

摘要翻译： 提供氯霉素衍生物用于制备用于产生专门用于氯霉素的抗体的抗原缀合物。 具体地，芳基氨基被衍生化以引入用于与抗原形成酰胺的非氧羰基。 然后将缀合物注射到脊椎动物中以产生以常规方式分离的抗血清，并在竞争性蛋白质结合测定中发现特别的用途。

公开(公告)号：US4489157A

公开(公告)日：1984-12-18

申请号：US306569

申请日：1981-09-28

申请人： Pyare L. Khanna ,  Evan S. Snyder ,  Prithipal Singh

发明人： Pyare L. Khanna ,  Evan S. Snyder ,  Prithipal Singh

IPC分类号： G01N33/94 ,  G01N33/54 ,  C07G7/00 ,  C12N9/96 ,  C12Q1/32

CPC分类号： G01N33/9446 ,  Y10S435/81

摘要： Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and finds particular use in competitive protein binding assays.

摘要翻译： 提供氯霉素衍生物用于制备用于产生专门用于氯霉素的抗体的抗原缀合物。 具体地，芳基氨基被衍生化以引入用于与抗原形成酰胺的非氧羰基。 然后将缀合物注射到脊椎动物中以产生以常规方式分离的抗血清，并且在竞争性蛋白质结合测定中特别有用。

公开(公告)号：US4489156A

公开(公告)日：1984-12-18

申请号：US256761

申请日：1981-04-23

申请人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

发明人： Pyare Khanna ,  Evan S. Snyder ,  Prithipal Singh

IPC分类号： G01N33/94 ,  G01N33/54 ,  C07G7/00 ,  C12N9/96 ,  C12Q1/32

CPC分类号： G01N33/9446 ,  Y10S435/81 ,  Y10S435/961 ,  Y10S435/964 ,  Y10S530/806 ,  Y10S530/807

摘要： Chloramphenicol derivatives are provided for use in the preparing of antigen conjugates for the production of antibodies specifically for chloramphenicol. Specifically, the aryl amino group is derivatized to introduce a non-oxocarbonyl group which is used for amide formation with an antigen. The conjugate is then injected into a vertebrate for production of antisera which is isolated in conventional ways and find particular use in competitive protein binding assays.

摘要翻译： 提供氯霉素衍生物用于制备用于产生专门用于氯霉素的抗体的抗原缀合物。 具体地，芳基氨基被衍生化以引入用于与抗原形成酰胺的非氧羰基。 然后将缀合物注射到脊椎动物中以产生以常规方式分离的抗血清，并在竞争性蛋白质结合测定中发现特别的用途。